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SH2D6 (SH2 domain containing 6)

Identity

Alias_symbol (synonym)FLJ35993
Other alias-
HGNC (Hugo) SH2D6
LocusID (NCBI) 284948
Atlas_Id 73195
Location 2p11.2  [Link to chromosome band 2p11]
Location_base_pair Starts at 85418931 and ends at 85437031 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SH2D6 (2p11.2) / NCOA2 (8q13.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SH2D6   30439
Cards
Entrez_Gene (NCBI)SH2D6  284948  SH2 domain containing 6
Aliases
GeneCards (Weizmann)SH2D6
Ensembl hg19 (Hinxton)ENSG00000152292 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000152292 [Gene_View]  chr2:85418931-85437031 [Contig_View]  SH2D6 [Vega]
ICGC DataPortalENSG00000152292
TCGA cBioPortalSH2D6
AceView (NCBI)SH2D6
Genatlas (Paris)SH2D6
WikiGenes284948
SOURCE (Princeton)SH2D6
Genetics Home Reference (NIH)SH2D6
Genomic and cartography
GoldenPath hg38 (UCSC)SH2D6  -     chr2:85418931-85437031 +  2p11.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SH2D6  -     2p11.2   [Description]    (hg19-Feb_2009)
EnsemblSH2D6 - 2p11.2 [CytoView hg19]  SH2D6 - 2p11.2 [CytoView hg38]
Mapping of homologs : NCBISH2D6 [Mapview hg19]  SH2D6 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AF450483 AK093312 AW293024 AY517502 BC110073
RefSeq transcript (Entrez)NM_198482 NM_201594
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SH2D6
Cluster EST : UnigeneHs.209542 [ NCBI ]
CGAP (NCI)Hs.209542
Alternative Splicing GalleryENSG00000152292
Gene ExpressionSH2D6 [ NCBI-GEO ]   SH2D6 [ EBI - ARRAY_EXPRESS ]   SH2D6 [ SEEK ]   SH2D6 [ MEM ]
Gene Expression Viewer (FireBrowse)SH2D6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)284948
GTEX Portal (Tissue expression)SH2D6
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ7Z4S9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ7Z4S9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ7Z4S9
Splice isoforms : SwissVarQ7Z4S9
PhosPhoSitePlusQ7Z4S9
Domaine pattern : Prosite (Expaxy)SH2 (PS50001)   
Domains : Interpro (EBI)SH2   
Domain families : Pfam (Sanger)SH2 (PF00017)   
Domain families : Pfam (NCBI)pfam00017   
Domain families : Smart (EMBL)SH2 (SM00252)  
Conserved Domain (NCBI)SH2D6
DMDM Disease mutations284948
Blocks (Seattle)SH2D6
SuperfamilyQ7Z4S9
Human Protein AtlasENSG00000152292
Peptide AtlasQ7Z4S9
HPRD14156
IPIIPI00394759   IPI00401786   IPI00657968   
Protein Interaction databases
DIP (DOE-UCLA)Q7Z4S9
IntAct (EBI)Q7Z4S9
FunCoupENSG00000152292
BioGRIDSH2D6
STRING (EMBL)SH2D6
ZODIACSH2D6
Ontologies - Pathways
QuickGOQ7Z4S9
Ontology : AmiGOtransmembrane receptor protein tyrosine kinase adaptor activity  SH3/SH2 adaptor activity  cytoplasm  immune response  transmembrane receptor protein tyrosine kinase signaling pathway  positive regulation of signal transduction  intracellular signal transduction  
Ontology : EGO-EBItransmembrane receptor protein tyrosine kinase adaptor activity  SH3/SH2 adaptor activity  cytoplasm  immune response  transmembrane receptor protein tyrosine kinase signaling pathway  positive regulation of signal transduction  intracellular signal transduction  
NDEx NetworkSH2D6
Atlas of Cancer Signalling NetworkSH2D6
Wikipedia pathwaysSH2D6
Orthology - Evolution
OrthoDB284948
GeneTree (enSembl)ENSG00000152292
Phylogenetic Trees/Animal Genes : TreeFamSH2D6
HOVERGENQ7Z4S9
HOGENOMQ7Z4S9
Homologs : HomoloGeneSH2D6
Homology/Alignments : Family Browser (UCSC)SH2D6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSH2D6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SH2D6
dbVarSH2D6
ClinVarSH2D6
1000_GenomesSH2D6 
Exome Variant ServerSH2D6
ExAC (Exome Aggregation Consortium)SH2D6 (select the gene name)
Genetic variants : HAPMAP284948
Genomic Variants (DGV)SH2D6 [DGVbeta]
DECIPHERSH2D6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSH2D6 
Mutations
ICGC Data PortalSH2D6 
TCGA Data PortalSH2D6 
Broad Tumor PortalSH2D6
OASIS PortalSH2D6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSH2D6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSH2D6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SH2D6
DgiDB (Drug Gene Interaction Database)SH2D6
DoCM (Curated mutations)SH2D6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SH2D6 (select a term)
intoGenSH2D6
Cancer3DSH2D6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenSH2D6
Genetic Testing Registry SH2D6
NextProtQ7Z4S9 [Medical]
TSGene284948
GENETestsSH2D6
Target ValidationSH2D6
Huge Navigator SH2D6 [HugePedia]
snp3D : Map Gene to Disease284948
BioCentury BCIQSH2D6
ClinGenSH2D6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD284948
Chemical/Pharm GKB GenePA162403243
Clinical trialSH2D6
Miscellaneous
canSAR (ICR)SH2D6 (select the gene name)
Probes
Litterature
PubMed3 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSH2D6
EVEXSH2D6
GoPubMedSH2D6
iHOPSH2D6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:40:36 CEST 2017

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