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SH3BP1 (SH3-domain binding protein 1)

Identity

Alias_symbol (synonym)ARHGAP43
Other alias
HGNC (Hugo) SH3BP1
LocusID (NCBI) 23616
Atlas_Id 73201
Location 22q13.1  [Link to chromosome band 22q13]
Location_base_pair Starts at 38035684 and ends at 38052050 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
SH3BP1 (22q13.1) / CACNA1I (22q13.1)SH3BP1 (22q13.1) / NDUFAF3 (3p21.31)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SH3BP1   10824
Cards
Entrez_Gene (NCBI)SH3BP1  23616  SH3-domain binding protein 1
AliasesARHGAP43
GeneCards (Weizmann)SH3BP1
Ensembl hg19 (Hinxton)ENSG00000100092 [Gene_View]  chr22:38035684-38052050 [Contig_View]  SH3BP1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000100092 [Gene_View]  chr22:38035684-38052050 [Contig_View]  SH3BP1 [Vega]
ICGC DataPortalENSG00000100092
TCGA cBioPortalSH3BP1
AceView (NCBI)SH3BP1
Genatlas (Paris)SH3BP1
WikiGenes23616
SOURCE (Princeton)SH3BP1
Genetics Home Reference (NIH)SH3BP1
Genomic and cartography
GoldenPath hg19 (UCSC)SH3BP1  -     chr22:38035684-38052050 +  22q13.1   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SH3BP1  -     22q13.1   [Description]    (hg38-Dec_2013)
EnsemblSH3BP1 - 22q13.1 [CytoView hg19]  SH3BP1 - 22q13.1 [CytoView hg38]
Mapping of homologs : NCBISH3BP1 [Mapview hg19]  SH3BP1 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK124370 AK126556 AK301163 AL157480 AW452539
RefSeq transcript (Entrez)NM_018957
RefSeq genomic (Entrez)NC_000022 NC_018933 NT_011520 NW_004929430
Consensus coding sequences : CCDS (NCBI)SH3BP1
Cluster EST : UnigeneHs.601143 [ NCBI ]
CGAP (NCI)Hs.601143
Alternative Splicing GalleryENSG00000100092
Gene ExpressionSH3BP1 [ NCBI-GEO ]   SH3BP1 [ EBI - ARRAY_EXPRESS ]   SH3BP1 [ SEEK ]   SH3BP1 [ MEM ]
Gene Expression Viewer (FireBrowse)SH3BP1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23616
GTEX Portal (Tissue expression)SH3BP1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y3L3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y3L3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y3L3
Splice isoforms : SwissVarQ9Y3L3
PhosPhoSitePlusQ9Y3L3
Domaine pattern : Prosite (Expaxy)BAR (PS51021)    RHOGAP (PS50238)   
Domains : Interpro (EBI)AH/BAR-dom    BAR_dom    Rho_GTPase_activation_prot    RhoGAP_dom   
Domain families : Pfam (Sanger)BAR (PF03114)    RhoGAP (PF00620)   
Domain families : Pfam (NCBI)pfam03114    pfam00620   
Domain families : Smart (EMBL)RhoGAP (SM00324)  
Conserved Domain (NCBI)SH3BP1
DMDM Disease mutations23616
Blocks (Seattle)SH3BP1
PDB (SRS)4J9D    4J9F   
PDB (PDBSum)4J9D    4J9F   
PDB (IMB)4J9D    4J9F   
PDB (RSDB)4J9D    4J9F   
Structural Biology KnowledgeBase4J9D    4J9F   
SCOP (Structural Classification of Proteins)4J9D    4J9F   
CATH (Classification of proteins structures)4J9D    4J9F   
SuperfamilyQ9Y3L3
Human Protein AtlasENSG00000100092
Peptide AtlasQ9Y3L3
HPRD10227
IPIIPI00456744   IPI01011491   IPI00456745   IPI00445123   IPI00444788   IPI00030415   IPI00925503   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y3L3
IntAct (EBI)Q9Y3L3
FunCoupENSG00000100092
BioGRIDSH3BP1
STRING (EMBL)SH3BP1
ZODIACSH3BP1
Ontologies - Pathways
QuickGOQ9Y3L3
Ontology : AmiGOGTPase activator activity  protein binding  cytoplasm  signal transduction  SH3 domain binding  positive regulation of GTPase activity  
Ontology : EGO-EBIGTPase activator activity  protein binding  cytoplasm  signal transduction  SH3 domain binding  positive regulation of GTPase activity  
NDEx NetworkSH3BP1
Atlas of Cancer Signalling NetworkSH3BP1
Wikipedia pathwaysSH3BP1
Orthology - Evolution
OrthoDB23616
GeneTree (enSembl)ENSG00000100092
Phylogenetic Trees/Animal Genes : TreeFamSH3BP1
HOVERGENQ9Y3L3
HOGENOMQ9Y3L3
Homologs : HomoloGeneSH3BP1
Homology/Alignments : Family Browser (UCSC)SH3BP1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSH3BP1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SH3BP1
dbVarSH3BP1
ClinVarSH3BP1
1000_GenomesSH3BP1 
Exome Variant ServerSH3BP1
ExAC (Exome Aggregation Consortium)SH3BP1 (select the gene name)
Genetic variants : HAPMAP23616
Genomic Variants (DGV)SH3BP1 [DGVbeta]
DECIPHER (Syndromes)22:38035684-38052050  ENSG00000100092
CONAN: Copy Number AnalysisSH3BP1 
Mutations
ICGC Data PortalSH3BP1 
TCGA Data PortalSH3BP1 
Broad Tumor PortalSH3BP1
OASIS PortalSH3BP1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSH3BP1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSH3BP1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SH3BP1
DgiDB (Drug Gene Interaction Database)SH3BP1
DoCM (Curated mutations)SH3BP1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SH3BP1 (select a term)
intoGenSH3BP1
Cancer3DSH3BP1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenSH3BP1
Genetic Testing Registry SH3BP1
NextProtQ9Y3L3 [Medical]
TSGene23616
GENETestsSH3BP1
Huge Navigator SH3BP1 [HugePedia]
snp3D : Map Gene to Disease23616
BioCentury BCIQSH3BP1
ClinGenSH3BP1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23616
Chemical/Pharm GKB GenePA35732
Clinical trialSH3BP1
Miscellaneous
canSAR (ICR)SH3BP1 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSH3BP1
EVEXSH3BP1
GoPubMedSH3BP1
iHOPSH3BP1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:43:04 CET 2017

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