Atlas of Genetics and Cytogenetics in Oncology and Haematology

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Taking over the Atlas
Dear Colleagues,
The Atlas, once more, is in great danger, and I will have to proceed to a collective economic lay-off of all the team involved in the Atlas before the begining of April 2015 (a foundation having suddenly withdrawn its commitment to support the Atlas). I ask you herein if any Scientific Society (a Society of Cytogenetics, of Clinical Genetics, of Hematology, or a Cancer Society, or any other...), any University and/or Hospital, any Charity, or any database would be interested in taking over the Atlas, in whole or in part. If taking charge of the whole lot is too big, a consortium of various actors could be the solution (I am myself trying to find partners). Could you please spread the information, contact the relevant authorities, and find partners.
Survival of the Atlas will be critically dependant upon your ability to find solutions (and urgently!).
Kind regards.
Jean-Loup Huret
Donations are also welcome
If each casual visitor gives 3 Euros or Dollars, the Atlas is saved in a week !
If each professional gives 100 Euros or Dollars once a year (now), the Atlas is saved in 2 weeks !
Don't let the Atlas imminent demise
Note: we send fiscal receipts for donations equal or above 50 Euros or Dollars

Donate (in Euros)

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SH3BP2 (SH3-domain binding protein 2)


Other names3BP-2
HGNC (Hugo) SH3BP2
LocusID (NCBI) 6452
Location 4p16.3
Location_base_pair Starts at 2794750 and ends at 2842823 bp from pter ( according to hg19-Feb_2009)

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute



External links

HGNC (Hugo)SH3BP2   10825
Entrez_Gene (NCBI)SH3BP2  6452  SH3-domain binding protein 2
GeneCards (Weizmann)SH3BP2
Ensembl hg19 (Hinxton)ENSG00000087266 [Gene_View]  chr4:2794750-2842823 [Contig_View]  SH3BP2 [Vega]
Ensembl hg38 (Hinxton)ENSG00000087266 [Gene_View]  chr4:2794750-2842823 [Contig_View]  SH3BP2 [Vega]
ICGC DataPortalENSG00000087266
AceView (NCBI)SH3BP2
Genatlas (Paris)SH3BP2
SOURCE (Princeton)SH3BP2
Genomic and cartography
GoldenPath hg19 (UCSC)SH3BP2  -     chr4:2794750-2842823 +  4p16.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SH3BP2  -     4p16.3   [Description]    (hg38-Dec_2013)
EnsemblSH3BP2 - 4p16.3 [CytoView hg19]  SH3BP2 - 4p16.3 [CytoView hg38]
Mapping of homologs : NCBISH3BP2 [Mapview hg19]  SH3BP2 [Mapview hg38]
OMIM118400   602104   
Gene and transcription
Genbank (Entrez)AB000462 AB000463 AF000936 AK124073 AK126537
RefSeq transcript (Entrez)NM_001122681 NM_001145855 NM_001145856 NM_003023
RefSeq genomic (Entrez)NC_000004 NC_018915 NG_011609 NT_006051 NW_004929314
Consensus coding sequences : CCDS (NCBI)SH3BP2
Cluster EST : UnigeneHs.167679 [ NCBI ]
CGAP (NCI)Hs.167679
Alternative Splicing : Fast-db (Paris)GSHG0022415
Alternative Splicing GalleryENSG00000087266
Gene ExpressionSH3BP2 [ NCBI-GEO ]     SH3BP2 [ SEEK ]   SH3BP2 [ MEM ]
SOURCE (Princeton)Expression in : [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP78314 (Uniprot)
NextProtP78314  [Medical]
With graphics : InterProP78314
Splice isoforms : SwissVarP78314 (Swissvar)
Domaine pattern : Prosite (Expaxy)PH_DOMAIN (PS50003)    SH2 (PS50001)   
Domains : Interpro (EBI)PH_domain    PH_like_dom    SH2   
Related proteins : CluSTrP78314
Domain families : Pfam (Sanger)PH (PF00169)    SH2 (PF00017)   
Domain families : Pfam (NCBI)pfam00169    pfam00017   
Domain families : Smart (EMBL)PH (SM00233)  SH2 (SM00252)  
DMDM Disease mutations6452
Blocks (Seattle)P78314
PDB (SRS)2CR4    3TWR   
PDB (PDBSum)2CR4    3TWR   
PDB (IMB)2CR4    3TWR   
PDB (RSDB)2CR4    3TWR   
Human Protein AtlasENSG00000087266
Peptide AtlasP78314
IPIIPI00219071   IPI00218997   IPI00922541   IPI00446438   IPI00926189   IPI00927717   IPI00964397   IPI00964137   IPI00965372   IPI00965585   IPI00963865   IPI00967096   
Protein Interaction databases
IntAct (EBI)P78314
Ontologies - Pathways
Ontology : AmiGOSH3/SH2 adaptor activity  protein binding  signal transduction  positive regulation of signal transduction  SH3 domain binding  
Ontology : EGO-EBISH3/SH2 adaptor activity  protein binding  signal transduction  positive regulation of signal transduction  SH3 domain binding  
Pathways : KEGGNatural killer cell mediated cytotoxicity   
Protein Interaction DatabaseSH3BP2
DoCM (Curated mutations)SH3BP2
Wikipedia pathwaysSH3BP2
Gene fusion - rearrangements
Polymorphisms : SNP, variants
NCBI Variation ViewerSH3BP2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SH3BP2
Exome Variant ServerSH3BP2
SNP (GeneSNP Utah)SH3BP2
Genetic variants : HAPMAPSH3BP2
Genomic Variants (DGV)SH3BP2 [DGVbeta]
ICGC Data PortalENSG00000087266 
Somatic Mutations in Cancer : COSMICSH3BP2 
CONAN: Copy Number AnalysisSH3BP2 
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] 
DECIPHER (Syndromes)4:2794750-2842823
Mutations and Diseases : HGMDSH3BP2
OMIM118400    602104   
NextProtP78314 [Medical]
Disease Genetic AssociationSH3BP2
Huge Navigator SH3BP2 [HugePedia]  SH3BP2 [HugeCancerGEM]
snp3D : Map Gene to Disease6452
DGIdb (Drug Gene Interaction db)SH3BP2
General knowledge
Homologs : HomoloGeneSH3BP2
Homology/Alignments : Family Browser (UCSC)SH3BP2
Phylogenetic Trees/Animal Genes : TreeFamSH3BP2
Chemical/Protein Interactions : CTD6452
Chemical/Pharm GKB GenePA35733
Clinical trialSH3BP2
Cancer Resource (Charite)ENSG00000087266
Other databases
PubMed52 Pubmed reference(s) in Entrez
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI


Written09-2002Dessen P, Le Minor S
Updated02-2015Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Sat Mar 28 17:17:00 CET 2015

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