Identity
HGNC
LOCATION
15q25.2
LOCUSID
ALIAS
CNSA3,EEN-B2,HsT19371,SH3D2C,SH3P13
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6457
MIM: 603362
HGNC: 10832
Ensembl: ENSG00000140600
Variants:
dbSNP: 6457
ClinVar: 6457
TCGA: ENSG00000140600
COSMIC: SH3GL3
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000140600 | ENST00000324537 | Q99963 |
| ENSG00000140600 | ENST00000427482 | Q99963 |
| ENSG00000140600 | ENST00000563901 | H3BRH8 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 37916731 | 2023 | LncRNA MIR210HG promotes the proliferation, migration, and invasion of lung cancer cells by inhibiting the transcription of SH3GL3. | 0 |
| 37916731 | 2023 | LncRNA MIR210HG promotes the proliferation, migration, and invasion of lung cancer cells by inhibiting the transcription of SH3GL3. | 0 |
| 33168185 | 2021 | SH3GL3 functions as a potent tumor suppressor in lung cancer in a SH3 domain dependent manner. | 5 |
| 33524871 | 2021 | SH3GL3 acts as a novel tumor suppressor in glioblastoma tumorigenesis by inhibiting STAT3 signaling. | 2 |
| 33168185 | 2021 | SH3GL3 functions as a potent tumor suppressor in lung cancer in a SH3 domain dependent manner. | 5 |
| 33524871 | 2021 | SH3GL3 acts as a novel tumor suppressor in glioblastoma tumorigenesis by inhibiting STAT3 signaling. | 2 |
| 32193381 | 2020 | Endophilin-A3 and Galectin-8 control the clathrin-independent endocytosis of CD166. | 35 |
| 32193381 | 2020 | Endophilin-A3 and Galectin-8 control the clathrin-independent endocytosis of CD166. | 35 |
| 27683032 | 2016 | The role of SH3GL3 in myeloma cell migration/invasion, stemness and chemo-resistance. | 7 |
| 27683032 | 2016 | The role of SH3GL3 in myeloma cell migration/invasion, stemness and chemo-resistance. | 7 |
| 21722156 | 2012 | Identification and functional validation of CDH11, PCSK6 and SH3GL3 as novel glioma invasion-associated candidate genes. | 27 |
| 22901147 | 2012 | Genome-wide analysis of aberrant DNA methylation for identification of potential biomarkers in colorectal cancer patients. | 10 |
| 21722156 | 2012 | Identification and functional validation of CDH11, PCSK6 and SH3GL3 as novel glioma invasion-associated candidate genes. | 27 |
| 22901147 | 2012 | Genome-wide analysis of aberrant DNA methylation for identification of potential biomarkers in colorectal cancer patients. | 10 |
| 20546612 | 2010 | The role of height-associated loci identified in genome wide association studies in the determination of pediatric stature. | 28 |
Citation
Dessen P
SH3GL3 (SH3 domain containing GRB2 like 3, endophilin A3)
Atlas Genet Cytogenet Oncol Haematol. 2013-02-01
Online version: http://atlasgeneticsoncology.org/gene/53167/sh3gl3
