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SH3GL3 (SH3 domain containing GRB2 like 3, endophilin A3)

Identity

Alias_namesSH3 domain containing GRB2 like 3
Alias_symbol (synonym)SH3D2C
SH3P13
CNSA3
EEN-B2
HsT19371
Other alias
HGNC (Hugo) SH3GL3
LocusID (NCBI) 6457
Atlas_Id 53167
Location 15q25.2  [Link to chromosome band 15q25]
Location_base_pair Starts at 83447228 and ends at 83618741 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SH3GL3 (15q25.2) / L3MBTL1 (20q13.12)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SH3GL3   10832
Cards
Entrez_Gene (NCBI)SH3GL3  6457  SH3 domain containing GRB2 like 3, endophilin A3
AliasesCNSA3; EEN-B2; HsT19371; SH3D2C; 
SH3P13
GeneCards (Weizmann)SH3GL3
Ensembl hg19 (Hinxton)ENSG00000140600 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000140600 [Gene_View]  chr15:83447228-83618741 [Contig_View]  SH3GL3 [Vega]
ICGC DataPortalENSG00000140600
TCGA cBioPortalSH3GL3
AceView (NCBI)SH3GL3
Genatlas (Paris)SH3GL3
WikiGenes6457
SOURCE (Princeton)SH3GL3
Genetics Home Reference (NIH)SH3GL3
Genomic and cartography
GoldenPath hg38 (UCSC)SH3GL3  -     chr15:83447228-83618741 +  15q25.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SH3GL3  -     15q25.2   [Description]    (hg19-Feb_2009)
EnsemblSH3GL3 - 15q25.2 [CytoView hg19]  SH3GL3 - 15q25.2 [CytoView hg38]
Mapping of homologs : NCBISH3GL3 [Mapview hg19]  SH3GL3 [Mapview hg38]
OMIM603362   
Gene and transcription
Genbank (Entrez)AF036269 AF036270 AF036271 AK307442 AK309086
RefSeq transcript (Entrez)NM_001301108 NM_001301109 NM_001324182 NM_001324183 NM_001324184 NM_001324185 NM_001324186 NM_001324187 NM_003027
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SH3GL3
Cluster EST : UnigeneHs.270055 [ NCBI ]
CGAP (NCI)Hs.270055
Alternative Splicing GalleryENSG00000140600
Gene ExpressionSH3GL3 [ NCBI-GEO ]   SH3GL3 [ EBI - ARRAY_EXPRESS ]   SH3GL3 [ SEEK ]   SH3GL3 [ MEM ]
Gene Expression Viewer (FireBrowse)SH3GL3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6457
GTEX Portal (Tissue expression)SH3GL3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ99963   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ99963  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ99963
Splice isoforms : SwissVarQ99963
PhosPhoSitePlusQ99963
Domaine pattern : Prosite (Expaxy)BAR (PS51021)    SH3 (PS50002)   
Domains : Interpro (EBI)AH/BAR-dom    BAR_dom    Endophilin-A    Endophilin-A3_BAR    SH3_2    SH3_domain   
Domain families : Pfam (Sanger)BAR (PF03114)    SH3_2 (PF07653)   
Domain families : Pfam (NCBI)pfam03114    pfam07653   
Domain families : Smart (EMBL)BAR (SM00721)  SH3 (SM00326)  
Conserved Domain (NCBI)SH3GL3
DMDM Disease mutations6457
Blocks (Seattle)SH3GL3
PDB (SRS)2EW3    2Z0V   
PDB (PDBSum)2EW3    2Z0V   
PDB (IMB)2EW3    2Z0V   
PDB (RSDB)2EW3    2Z0V   
Structural Biology KnowledgeBase2EW3    2Z0V   
SCOP (Structural Classification of Proteins)2EW3    2Z0V   
CATH (Classification of proteins structures)2EW3    2Z0V   
SuperfamilyQ99963
Human Protein AtlasENSG00000140600
Peptide AtlasQ99963
HPRD04528
IPIIPI00019172   IPI00216201   IPI00216202   IPI00216203   IPI00924807   
Protein Interaction databases
DIP (DOE-UCLA)Q99963
IntAct (EBI)Q99963
FunCoupENSG00000140600
BioGRIDSH3GL3
STRING (EMBL)SH3GL3
ZODIACSH3GL3
Ontologies - Pathways
QuickGOQ99963
Ontology : AmiGOprotein binding  early endosome  endocytosis  signal transduction  central nervous system development  lipid binding  early endosome membrane  identical protein binding  extracellular exosome  
Ontology : EGO-EBIprotein binding  early endosome  endocytosis  signal transduction  central nervous system development  lipid binding  early endosome membrane  identical protein binding  extracellular exosome  
Pathways : KEGGEndocytosis   
NDEx NetworkSH3GL3
Atlas of Cancer Signalling NetworkSH3GL3
Wikipedia pathwaysSH3GL3
Orthology - Evolution
OrthoDB6457
GeneTree (enSembl)ENSG00000140600
Phylogenetic Trees/Animal Genes : TreeFamSH3GL3
HOVERGENQ99963
HOGENOMQ99963
Homologs : HomoloGeneSH3GL3
Homology/Alignments : Family Browser (UCSC)SH3GL3
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSH3GL3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SH3GL3
dbVarSH3GL3
ClinVarSH3GL3
1000_GenomesSH3GL3 
Exome Variant ServerSH3GL3
ExAC (Exome Aggregation Consortium)SH3GL3 (select the gene name)
Genetic variants : HAPMAP6457
Genomic Variants (DGV)SH3GL3 [DGVbeta]
DECIPHERSH3GL3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSH3GL3 
Mutations
ICGC Data PortalSH3GL3 
TCGA Data PortalSH3GL3 
Broad Tumor PortalSH3GL3
OASIS PortalSH3GL3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSH3GL3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSH3GL3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SH3GL3
DgiDB (Drug Gene Interaction Database)SH3GL3
DoCM (Curated mutations)SH3GL3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SH3GL3 (select a term)
intoGenSH3GL3
Cancer3DSH3GL3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603362   
Orphanet
MedgenSH3GL3
Genetic Testing Registry SH3GL3
NextProtQ99963 [Medical]
TSGene6457
GENETestsSH3GL3
Huge Navigator SH3GL3 [HugePedia]
snp3D : Map Gene to Disease6457
BioCentury BCIQSH3GL3
ClinGenSH3GL3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6457
Chemical/Pharm GKB GenePA35738
Clinical trialSH3GL3
Miscellaneous
canSAR (ICR)SH3GL3 (select the gene name)
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSH3GL3
EVEXSH3GL3
GoPubMedSH3GL3
iHOPSH3GL3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:37:04 CEST 2017

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