SH3GLB2 (SH3 domain containing GRB2 like, endophilin B2)

2014-11-01  

Identity

HGNC
LOCATION
9q34.11
LOCUSID
ALIAS
PP6569,PP9455,RRIG1
FUSION GENES

Other Information

Locus ID:

NCBI: 56904
MIM: 609288
HGNC: 10834
Ensembl: ENSG00000148341

Variants:

dbSNP: 56904
ClinVar: 56904
TCGA: ENSG00000148341
COSMIC: SH3GLB2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000148341ENST00000372554Q9NR46
ENSG00000148341ENST00000372559Q9NR46
ENSG00000148341ENST00000372559A0A024R896
ENSG00000148341ENST00000372564Q9NR46
ENSG00000148341ENST00000372564A0A024R896
ENSG00000148341ENST00000416230F8WFB9
ENSG00000148341ENST00000416629B7ZC39
ENSG00000148341ENST00000417224B7ZC38
ENSG00000148341ENST00000425236H7C1Z6
ENSG00000148341ENST00000455407G5E9J1

Expression (GTEx)

0
50
100
150
200

Pathways

PathwaySourceExternal ID
EndocytosisKEGGko04144
EndocytosisKEGGhsa04144

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
183031162008SPAS-1 (stimulator of prostatic adenocarcinoma-specific T cells)/SH3GLB2: A prostate tumor antigen identified by CTLA-4 blockade.23
284554442017Endophilin B2 facilitates endosome maturation in response to growth factor stimulation, autophagy induction, and influenza A virus infection.5
239213852013The Bin/amphiphysin/Rvs (BAR) domain protein endophilin B2 interacts with plectin and controls perinuclear cytoskeletal architecture.4
271121212016Endophilin B2 promotes inner mitochondrial membrane degradation by forming heterodimers with Endophilin B1 during mitophagy.3

Citation

Dessen P

SH3GLB2 (SH3 domain containing GRB2 like, endophilin B2)

Atlas Genet Cytogenet Oncol Haematol. 2014-11-01

Online version: http://atlasgeneticsoncology.org/gene/73209/sh3glb2