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SH3GLB2 (SH3 domain containing GRB2 like, endophilin B2)

Identity

Alias (NCBI)PP6569
PP9455
RRIG1
HGNC (Hugo) SH3GLB2
HGNC Alias symbKIAA1848
HGNC Previous nameSH3-domain, GRB2-like, endophilin B2
LocusID (NCBI) 56904
Atlas_Id 73209
Location 9q34.11  [Link to chromosome band 9q34]
Location_base_pair Starts at 129007793 and ends at 129028353 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EIF4G2 (11p15.3) / SH3GLB2 (9q34.11)OCIAD1 (4p11) / SH3GLB2 (9q34.11)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)SH3GLB2   10834
Cards
Entrez_Gene (NCBI)SH3GLB2    SH3 domain containing GRB2 like, endophilin B2
AliasesPP6569; PP9455; RRIG1
GeneCards (Weizmann)SH3GLB2
Ensembl hg19 (Hinxton)ENSG00000148341 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000148341 [Gene_View]  ENSG00000148341 [Sequence]  chr9:129007793-129028353 [Contig_View]  SH3GLB2 [Vega]
ICGC DataPortalENSG00000148341
TCGA cBioPortalSH3GLB2
AceView (NCBI)SH3GLB2
Genatlas (Paris)SH3GLB2
SOURCE (Princeton)SH3GLB2
Genetics Home Reference (NIH)SH3GLB2
Genomic and cartography
GoldenPath hg38 (UCSC)SH3GLB2  -     chr9:129007793-129028353 -  9q34.11   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SH3GLB2  -     9q34.11   [Description]    (hg19-Feb_2009)
GoldenPathSH3GLB2 - 9q34.11 [CytoView hg19]  SH3GLB2 - 9q34.11 [CytoView hg38]
ImmunoBaseENSG00000148341
Genome Data Viewer NCBISH3GLB2 [Mapview hg19]  
OMIM609288   
Gene and transcription
Genbank (Entrez)AB058751 AF257319 AF258589 AF370426 AF370433
RefSeq transcript (Entrez)NM_001287045 NM_001287046 NM_001369913 NM_001369914 NM_001369915 NM_020145
Consensus coding sequences : CCDS (NCBI)SH3GLB2
Gene ExpressionSH3GLB2 [ NCBI-GEO ]   SH3GLB2 [ EBI - ARRAY_EXPRESS ]   SH3GLB2 [ SEEK ]   SH3GLB2 [ MEM ]
Gene Expression Viewer (FireBrowse)SH3GLB2 [ Firebrowse - Broad ]
GenevisibleExpression of SH3GLB2 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)56904
GTEX Portal (Tissue expression)SH3GLB2
Human Protein AtlasENSG00000148341-SH3GLB2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NR46   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NR46  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NR46
PhosPhoSitePlusQ9NR46
Domaine pattern : Prosite (Expaxy)BAR (PS51021)    SH3 (PS50002)   
Domains : Interpro (EBI)AH/BAR_dom_sf    BAR_dom    Endophilin_B2_SH3    SH3-like_dom_sf    SH3_domain   
Domain families : Pfam (Sanger)BAR (PF03114)    SH3_9 (PF14604)   
Domain families : Pfam (NCBI)pfam03114    pfam14604   
Domain families : Smart (EMBL)BAR (SM00721)  SH3 (SM00326)  
Conserved Domain (NCBI)SH3GLB2
SuperfamilyQ9NR46
AlphaFold pdb e-kbQ9NR46   
Human Protein Atlas [tissue]ENSG00000148341-SH3GLB2 [tissue]
HPRD15334
Protein Interaction databases
DIP (DOE-UCLA)Q9NR46
IntAct (EBI)Q9NR46
BioGRIDSH3GLB2
STRING (EMBL)SH3GLB2
ZODIACSH3GLB2
Ontologies - Pathways
QuickGOQ9NR46
Ontology : AmiGOprotein binding  nucleoplasm  cytoplasm  cytosol  identical protein binding  cadherin binding  
Ontology : EGO-EBIprotein binding  nucleoplasm  cytoplasm  cytosol  identical protein binding  cadherin binding  
Pathways : BIOCARTACBL mediated ligand-induced downregulation of EGF receptors [Genes]   
NDEx NetworkSH3GLB2
Atlas of Cancer Signalling NetworkSH3GLB2
Wikipedia pathwaysSH3GLB2
Orthology - Evolution
OrthoDB56904
GeneTree (enSembl)ENSG00000148341
Phylogenetic Trees/Animal Genes : TreeFamSH3GLB2
Homologs : HomoloGeneSH3GLB2
Homology/Alignments : Family Browser (UCSC)SH3GLB2
Gene fusions - Rearrangements
Fusion : QuiverSH3GLB2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSH3GLB2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SH3GLB2
dbVarSH3GLB2
ClinVarSH3GLB2
MonarchSH3GLB2
1000_GenomesSH3GLB2 
Exome Variant ServerSH3GLB2
GNOMAD BrowserENSG00000148341
Varsome BrowserSH3GLB2
ACMGSH3GLB2 variants
VarityQ9NR46
Genomic Variants (DGV)SH3GLB2 [DGVbeta]
DECIPHERSH3GLB2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSH3GLB2 
Mutations
ICGC Data PortalSH3GLB2 
TCGA Data PortalSH3GLB2 
Broad Tumor PortalSH3GLB2
OASIS PortalSH3GLB2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSH3GLB2  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSH3GLB2
Mutations and Diseases : HGMDSH3GLB2
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSH3GLB2
DgiDB (Drug Gene Interaction Database)SH3GLB2
DoCM (Curated mutations)SH3GLB2
CIViC (Clinical Interpretations of Variants in Cancer)SH3GLB2
Cancer3DSH3GLB2
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609288   
Orphanet
DisGeNETSH3GLB2
MedgenSH3GLB2
Genetic Testing Registry SH3GLB2
NextProtQ9NR46 [Medical]
GENETestsSH3GLB2
Target ValidationSH3GLB2
Huge Navigator SH3GLB2 [HugePedia]
ClinGenSH3GLB2
Clinical trials, drugs, therapy
MyCancerGenomeSH3GLB2
Protein Interactions : CTDSH3GLB2
Pharm GKB GenePA35740
PharosQ9NR46
Clinical trialSH3GLB2
Miscellaneous
canSAR (ICR)SH3GLB2
HarmonizomeSH3GLB2
DataMed IndexSH3GLB2
Probes
Litterature
PubMed40 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSH3GLB2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:20:27 CEST 2021

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