Identity
HGNC
LOCATION
Xp22.12
LOCUSID
ALIAS
AGMX2,CD2BP3,CIN85,GIG10,HSB-1,HSB1,IMD61,MIG18
FUSION GENES
Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 30011
MIM: 300374
HGNC: 13867
Ensembl: ENSG00000147010
Variants:
dbSNP: 30011
ClinVar: 30011
TCGA: ENSG00000147010
COSMIC: SH3KBP1
RNA/Proteins
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 33179079 | 2021 | High expression of CIN85 promotes proliferation and invasion of human esophageal squamous cell carcinoma. | 2 |
| 33430321 | 2021 | In Silico Identification of Potential Druggable Binding Sites on CIN85 SH3 Domain. | 3 |
| 33627783 | 2021 | E3 ligase-inactivation rewires CBL interactome to elicit oncogenesis by hijacking RTK-CBL-CIN85 axis. | 6 |
| 33179079 | 2021 | High expression of CIN85 promotes proliferation and invasion of human esophageal squamous cell carcinoma. | 2 |
| 33430321 | 2021 | In Silico Identification of Potential Druggable Binding Sites on CIN85 SH3 Domain. | 3 |
| 33627783 | 2021 | E3 ligase-inactivation rewires CBL interactome to elicit oncogenesis by hijacking RTK-CBL-CIN85 axis. | 6 |
| 31142511 | 2019 | The Pro-Oncogenic Adaptor CIN85 Acts as an Inhibitory Binding Partner of Hypoxia-Inducible Factor Prolyl Hydroxylase 2. | 5 |
| 31142511 | 2019 | The Pro-Oncogenic Adaptor CIN85 Acts as an Inhibitory Binding Partner of Hypoxia-Inducible Factor Prolyl Hydroxylase 2. | 5 |
| 29636373 | 2018 | Germline deletion of CIN85 in humans with X chromosome-linked antibody deficiency. | 12 |
| 30089695 | 2018 | Human Cytomegalovirus UL135 Interacts with Host Adaptor Proteins To Regulate Epidermal Growth Factor Receptor and Reactivation from Latency. | 29 |
| 29636373 | 2018 | Germline deletion of CIN85 in humans with X chromosome-linked antibody deficiency. | 12 |
| 30089695 | 2018 | Human Cytomegalovirus UL135 Interacts with Host Adaptor Proteins To Regulate Epidermal Growth Factor Receptor and Reactivation from Latency. | 29 |
| 27334924 | 2016 | A Novel Interaction of the Catalytic Subunit of Protein Phosphatase 2A with the Adaptor Protein CIN85 Suppresses Phosphatase Activity and Facilitates Platelet Outside-in αIIbβ3 Integrin Signaling. | 2 |
| 27353366 | 2016 | The adaptor protein CIN85 assembles intracellular signaling clusters for B cell activation. | 13 |
| 29227594 | 2016 | Transcriptional regulation of NOX genes express ion in human breast adenocarcinoma MCF-7 cells is modulated by adaptor protein Ruk/CIN 85. | 2 |
Citation
Dessen P
SH3KBP1 (SH3 domain containing kinase binding protein 1)
Atlas Genet Cytogenet Oncol Haematol. 2003-06-01
Online version: http://atlasgeneticsoncology.org/gene/42284/sh3kbp1
