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SH3RF2 (SH3 domain containing ring finger 2)

Identity

Alias_namesPPP1R39
protein phosphatase 1, regulatory subunit 39
Alias_symbol (synonym)FLJ23654
RNF158
Hepp1
POSHER
Other aliasHEPP1
HGNC (Hugo) SH3RF2
LocusID (NCBI) 153769
Atlas_Id 73212
Location 5q32  [Link to chromosome band 5q32]
Location_base_pair Starts at 145936563 and ends at 146063316 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SH3RF2 (5q32) / TANC1 (2q24.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SH3RF2   26299
Cards
Entrez_Gene (NCBI)SH3RF2  153769  SH3 domain containing ring finger 2
AliasesHEPP1; POSHER; PPP1R39; RNF158
GeneCards (Weizmann)SH3RF2
Ensembl hg19 (Hinxton)ENSG00000156463 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000156463 [Gene_View]  chr5:145936563-146063316 [Contig_View]  SH3RF2 [Vega]
ICGC DataPortalENSG00000156463
TCGA cBioPortalSH3RF2
AceView (NCBI)SH3RF2
Genatlas (Paris)SH3RF2
WikiGenes153769
SOURCE (Princeton)SH3RF2
Genetics Home Reference (NIH)SH3RF2
Genomic and cartography
GoldenPath hg38 (UCSC)SH3RF2  -     chr5:145936563-146063316 +  5q32   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SH3RF2  -     5q32   [Description]    (hg19-Feb_2009)
EnsemblSH3RF2 - 5q32 [CytoView hg19]  SH3RF2 - 5q32 [CytoView hg38]
Mapping of homologs : NCBISH3RF2 [Mapview hg19]  SH3RF2 [Mapview hg38]
OMIM613377   
Gene and transcription
Genbank (Entrez)AK058046 AK074234 AK292576 AK302024 AL833297
RefSeq transcript (Entrez)NM_152550
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SH3RF2
Cluster EST : UnigeneHs.443728 [ NCBI ]
CGAP (NCI)Hs.443728
Alternative Splicing GalleryENSG00000156463
Gene ExpressionSH3RF2 [ NCBI-GEO ]   SH3RF2 [ EBI - ARRAY_EXPRESS ]   SH3RF2 [ SEEK ]   SH3RF2 [ MEM ]
Gene Expression Viewer (FireBrowse)SH3RF2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)153769
GTEX Portal (Tissue expression)SH3RF2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TEC5   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TEC5  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TEC5
Splice isoforms : SwissVarQ8TEC5
Catalytic activity : Enzyme2.3.2.27 [ Enzyme-Expasy ]   2.3.2.272.3.2.27 [ IntEnz-EBI ]   2.3.2.27 [ BRENDA ]   2.3.2.27 [ KEGG ]   
PhosPhoSitePlusQ8TEC5
Domaine pattern : Prosite (Expaxy)SH3 (PS50002)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)SH3_2    SH3_domain    SH3RF2    Znf-RING_LisH    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)SH3_1 (PF00018)    SH3_2 (PF07653)    SH3_9 (PF14604)    zf-RING_UBOX (PF13445)   
Domain families : Pfam (NCBI)pfam00018    pfam07653    pfam14604    pfam13445   
Domain families : Smart (EMBL)RING (SM00184)  SH3 (SM00326)  
Conserved Domain (NCBI)SH3RF2
DMDM Disease mutations153769
Blocks (Seattle)SH3RF2
SuperfamilyQ8TEC5
Human Protein AtlasENSG00000156463
Peptide AtlasQ8TEC5
HPRD10229
IPIIPI00152705   IPI00815730   IPI00985170   IPI01018868   
Protein Interaction databases
DIP (DOE-UCLA)Q8TEC5
IntAct (EBI)Q8TEC5
FunCoupENSG00000156463
BioGRIDSH3RF2
STRING (EMBL)SH3RF2
ZODIACSH3RF2
Ontologies - Pathways
QuickGOQ8TEC5
Ontology : AmiGOprotein phosphatase inhibitor activity  protein binding  nucleoplasm  protein phosphatase 1 binding  zinc ion binding  negative regulation of phosphatase activity  protein ubiquitination  transferase activity  phosphatase binding  
Ontology : EGO-EBIprotein phosphatase inhibitor activity  protein binding  nucleoplasm  protein phosphatase 1 binding  zinc ion binding  negative regulation of phosphatase activity  protein ubiquitination  transferase activity  phosphatase binding  
NDEx NetworkSH3RF2
Atlas of Cancer Signalling NetworkSH3RF2
Wikipedia pathwaysSH3RF2
Orthology - Evolution
OrthoDB153769
GeneTree (enSembl)ENSG00000156463
Phylogenetic Trees/Animal Genes : TreeFamSH3RF2
HOVERGENQ8TEC5
HOGENOMQ8TEC5
Homologs : HomoloGeneSH3RF2
Homology/Alignments : Family Browser (UCSC)SH3RF2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSH3RF2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SH3RF2
dbVarSH3RF2
ClinVarSH3RF2
1000_GenomesSH3RF2 
Exome Variant ServerSH3RF2
ExAC (Exome Aggregation Consortium)SH3RF2 (select the gene name)
Genetic variants : HAPMAP153769
Genomic Variants (DGV)SH3RF2 [DGVbeta]
DECIPHERSH3RF2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSH3RF2 
Mutations
ICGC Data PortalSH3RF2 
TCGA Data PortalSH3RF2 
Broad Tumor PortalSH3RF2
OASIS PortalSH3RF2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSH3RF2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSH3RF2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SH3RF2
DgiDB (Drug Gene Interaction Database)SH3RF2
DoCM (Curated mutations)SH3RF2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SH3RF2 (select a term)
intoGenSH3RF2
Cancer3DSH3RF2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM613377   
Orphanet
MedgenSH3RF2
Genetic Testing Registry SH3RF2
NextProtQ8TEC5 [Medical]
TSGene153769
GENETestsSH3RF2
Target ValidationSH3RF2
Huge Navigator SH3RF2 [HugePedia]
snp3D : Map Gene to Disease153769
BioCentury BCIQSH3RF2
ClinGenSH3RF2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD153769
Chemical/Pharm GKB GenePA134944983
Clinical trialSH3RF2
Miscellaneous
canSAR (ICR)SH3RF2 (select the gene name)
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSH3RF2
EVEXSH3RF2
GoPubMedSH3RF2
iHOPSH3RF2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:40:39 CEST 2017

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