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SH3RF3 (SH3 domain containing ring finger 3)

Identity

Alias (NCBI)POSH2
SH3MD4
HGNC (Hugo) SH3RF3
HGNC Alias symbFLJ00204
POSH2
HGNC Previous nameSH3MD4
HGNC Previous nameSH3 multiple domains 4
LocusID (NCBI) 344558
Atlas_Id 73213
Location 2q13  [Link to chromosome band 2q13]
Location_base_pair Starts at 109129205 and ends at 109504634 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
EXOC2 (6p25.3) / SH3RF3 (2q12.3)PBX4 (19p13.11) / SH3RF3 (2q12.3)SH3RF3 (2q12.3) / PPP1R16B (20q11.23)
SH3RF3 (2q12.3) / SH3RF3 (2q12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 



External links

 

Nomenclature
HGNC (Hugo)SH3RF3   24699
Cards
Entrez_Gene (NCBI)SH3RF3    SH3 domain containing ring finger 3
AliasesPOSH2; SH3MD4
GeneCards (Weizmann)SH3RF3
Ensembl hg19 (Hinxton)ENSG00000172985 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000172985 [Gene_View]  ENSG00000172985 [Sequence]  chr2:109129205-109504634 [Contig_View]  SH3RF3 [Vega]
ICGC DataPortalENSG00000172985
TCGA cBioPortalSH3RF3
AceView (NCBI)SH3RF3
Genatlas (Paris)SH3RF3
SOURCE (Princeton)SH3RF3
Genetics Home Reference (NIH)SH3RF3
Genomic and cartography
GoldenPath hg38 (UCSC)SH3RF3  -     chr2:109129205-109504634 +  2q13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SH3RF3  -     2q13   [Description]    (hg19-Feb_2009)
GoldenPathSH3RF3 - 2q13 [CytoView hg19]  SH3RF3 - 2q13 [CytoView hg38]
ImmunoBaseENSG00000172985
Genome Data Viewer NCBISH3RF3 [Mapview hg19]  
OMIM618933   
Gene and transcription
Genbank (Entrez)AA916456 AK074131 AK093821 AL831825 DQ307286
RefSeq transcript (Entrez)NM_001099289
Consensus coding sequences : CCDS (NCBI)SH3RF3
Gene ExpressionSH3RF3 [ NCBI-GEO ]   SH3RF3 [ EBI - ARRAY_EXPRESS ]   SH3RF3 [ SEEK ]   SH3RF3 [ MEM ]
Gene Expression Viewer (FireBrowse)SH3RF3 [ Firebrowse - Broad ]
GenevisibleExpression of SH3RF3 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)344558
GTEX Portal (Tissue expression)SH3RF3
Human Protein AtlasENSG00000172985-SH3RF3 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TEJ3   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TEJ3  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TEJ3
PhosPhoSitePlusQ8TEJ3
Domaine pattern : Prosite (Expaxy)SH3 (PS50002)    ZF_RING_1 (PS00518)    ZF_RING_2 (PS50089)   
Domains : Interpro (EBI)SH3-like_dom_sf    SH3_domain    SH3RF1/SH3RF3_SH3_4    SH3RF3    SH3RF3_SH3_3    Znf_C3HC4_RING-type    Znf_RING    Znf_RING/FYVE/PHD    Znf_RING_CS   
Domain families : Pfam (Sanger)SH3_1 (PF00018)    SH3_9 (PF14604)    zf-C3HC4 (PF00097)   
Domain families : Pfam (NCBI)pfam00018    pfam14604    pfam00097   
Domain families : Smart (EMBL)RING (SM00184)  SH3 (SM00326)  
Conserved Domain (NCBI)SH3RF3
SuperfamilyQ8TEJ3
AlphaFold pdb e-kbQ8TEJ3   
Human Protein Atlas [tissue]ENSG00000172985-SH3RF3 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q8TEJ3
IntAct (EBI)Q8TEJ3
BioGRIDSH3RF3
STRING (EMBL)SH3RF3
ZODIACSH3RF3
Ontologies - Pathways
QuickGOQ8TEJ3
Ontology : AmiGOprotein binding  apoptotic process  positive regulation of JNK cascade  metal ion binding  protein autoubiquitination  ubiquitin protein ligase activity  
Ontology : EGO-EBIprotein binding  apoptotic process  positive regulation of JNK cascade  metal ion binding  protein autoubiquitination  ubiquitin protein ligase activity  
NDEx NetworkSH3RF3
Atlas of Cancer Signalling NetworkSH3RF3
Wikipedia pathwaysSH3RF3
Orthology - Evolution
OrthoDB344558
GeneTree (enSembl)ENSG00000172985
Phylogenetic Trees/Animal Genes : TreeFamSH3RF3
Homologs : HomoloGeneSH3RF3
Homology/Alignments : Family Browser (UCSC)SH3RF3
Gene fusions - Rearrangements
Fusion : QuiverSH3RF3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSH3RF3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SH3RF3
dbVarSH3RF3
ClinVarSH3RF3
MonarchSH3RF3
1000_GenomesSH3RF3 
Exome Variant ServerSH3RF3
GNOMAD BrowserENSG00000172985
Varsome BrowserSH3RF3
ACMGSH3RF3 variants
VarityQ8TEJ3
Genomic Variants (DGV)SH3RF3 [DGVbeta]
DECIPHERSH3RF3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSH3RF3 
Mutations
ICGC Data PortalSH3RF3 
TCGA Data PortalSH3RF3 
Broad Tumor PortalSH3RF3
OASIS PortalSH3RF3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSH3RF3  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSH3RF3
Mutations and Diseases : HGMDSH3RF3
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSH3RF3
DgiDB (Drug Gene Interaction Database)SH3RF3
DoCM (Curated mutations)SH3RF3
CIViC (Clinical Interpretations of Variants in Cancer)SH3RF3
Cancer3DSH3RF3
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM618933   
Orphanet
DisGeNETSH3RF3
MedgenSH3RF3
Genetic Testing Registry SH3RF3
NextProtQ8TEJ3 [Medical]
GENETestsSH3RF3
Target ValidationSH3RF3
Huge Navigator SH3RF3 [HugePedia]
ClinGenSH3RF3
Clinical trials, drugs, therapy
MyCancerGenomeSH3RF3
Protein Interactions : CTDSH3RF3
Pharm GKB GenePA162403291
PharosQ8TEJ3
Clinical trialSH3RF3
Miscellaneous
canSAR (ICR)SH3RF3
HarmonizomeSH3RF3
DataMed IndexSH3RF3
Probes
Litterature
PubMed10 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSH3RF3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 16:20:28 CEST 2021

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