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SHPK (sedoheptulokinase)

Identity

Alias_namesCARKL
carbohydrate kinase-like
Alias_symbol (synonym)SHK
Other alias
HGNC (Hugo) SHPK
LocusID (NCBI) 23729
Atlas_Id 73233
Location 17p13.2  [Link to chromosome band 17p13]
Location_base_pair Starts at 3511556 and ends at 3539616 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
ADPRHL2 (1p34.3) / SHPK (17p13.2)SHPK (17p13.2) / TAX1BP3 (17p13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SHPK   1492
Cards
Entrez_Gene (NCBI)SHPK  23729  sedoheptulokinase
AliasesCARKL; SHK
GeneCards (Weizmann)SHPK
Ensembl hg19 (Hinxton)ENSG00000197417 [Gene_View]  chr17:3511556-3539616 [Contig_View]  SHPK [Vega]
Ensembl hg38 (Hinxton)ENSG00000197417 [Gene_View]  chr17:3511556-3539616 [Contig_View]  SHPK [Vega]
ICGC DataPortalENSG00000197417
TCGA cBioPortalSHPK
AceView (NCBI)SHPK
Genatlas (Paris)SHPK
WikiGenes23729
SOURCE (Princeton)SHPK
Genetics Home Reference (NIH)SHPK
Genomic and cartography
GoldenPath hg19 (UCSC)SHPK  -     chr17:3511556-3539616 -  17p13.2   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SHPK  -     17p13.2   [Description]    (hg38-Dec_2013)
EnsemblSHPK - 17p13.2 [CytoView hg19]  SHPK - 17p13.2 [CytoView hg38]
Mapping of homologs : NCBISHPK [Mapview hg19]  SHPK [Mapview hg38]
OMIM605060   
Gene and transcription
Genbank (Entrez)AF163573 AK055609 AK057020 AK057040 AK298360
RefSeq transcript (Entrez)NM_013276
RefSeq genomic (Entrez)NC_000017 NC_018928 NT_010718 NW_004929405
Consensus coding sequences : CCDS (NCBI)SHPK
Cluster EST : UnigeneHs.579217 [ NCBI ]
CGAP (NCI)Hs.579217
Alternative Splicing GalleryENSG00000197417
Gene ExpressionSHPK [ NCBI-GEO ]   SHPK [ EBI - ARRAY_EXPRESS ]   SHPK [ SEEK ]   SHPK [ MEM ]
Gene Expression Viewer (FireBrowse)SHPK [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)23729
GTEX Portal (Tissue expression)SHPK
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UHJ6   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UHJ6  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UHJ6
Splice isoforms : SwissVarQ9UHJ6
Catalytic activity : Enzyme2.7.1.14 [ Enzyme-Expasy ]   2.7.1.142.7.1.14 [ IntEnz-EBI ]   2.7.1.14 [ BRENDA ]   2.7.1.14 [ KEGG ]   
PhosPhoSitePlusQ9UHJ6
Domains : Interpro (EBI)Carb_kinase_FGGY_N    Sedoheptulokinase   
Domain families : Pfam (Sanger)FGGY_N (PF00370)   
Domain families : Pfam (NCBI)pfam00370   
Conserved Domain (NCBI)SHPK
DMDM Disease mutations23729
Blocks (Seattle)SHPK
SuperfamilyQ9UHJ6
Human Protein AtlasENSG00000197417
Peptide AtlasQ9UHJ6
HPRD05451
IPIIPI00005914   
Protein Interaction databases
DIP (DOE-UCLA)Q9UHJ6
IntAct (EBI)Q9UHJ6
FunCoupENSG00000197417
BioGRIDSHPK
STRING (EMBL)SHPK
ZODIACSHPK
Ontologies - Pathways
QuickGOQ9UHJ6
Ontology : AmiGOATP binding  cytoplasm  cytoplasm  carbohydrate metabolic process  pentose-phosphate shunt, non-oxidative branch  phosphorylation  cellular response to interleukin-13  regulation of macrophage activation  carbohydrate phosphorylation  sedoheptulokinase activity  regulation of inflammatory response  cellular response to lipopolysaccharide  cellular response to interleukin-4  
Ontology : EGO-EBIATP binding  cytoplasm  cytoplasm  carbohydrate metabolic process  pentose-phosphate shunt, non-oxidative branch  phosphorylation  cellular response to interleukin-13  regulation of macrophage activation  carbohydrate phosphorylation  sedoheptulokinase activity  regulation of inflammatory response  cellular response to lipopolysaccharide  cellular response to interleukin-4  
NDEx NetworkSHPK
Atlas of Cancer Signalling NetworkSHPK
Wikipedia pathwaysSHPK
Orthology - Evolution
OrthoDB23729
GeneTree (enSembl)ENSG00000197417
Phylogenetic Trees/Animal Genes : TreeFamSHPK
HOVERGENQ9UHJ6
HOGENOMQ9UHJ6
Homologs : HomoloGeneSHPK
Homology/Alignments : Family Browser (UCSC)SHPK
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSHPK [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SHPK
dbVarSHPK
ClinVarSHPK
1000_GenomesSHPK 
Exome Variant ServerSHPK
ExAC (Exome Aggregation Consortium)SHPK (select the gene name)
Genetic variants : HAPMAP23729
Genomic Variants (DGV)SHPK [DGVbeta]
DECIPHER (Syndromes)17:3511556-3539616  ENSG00000197417
CONAN: Copy Number AnalysisSHPK 
Mutations
ICGC Data PortalSHPK 
TCGA Data PortalSHPK 
Broad Tumor PortalSHPK
OASIS PortalSHPK [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSHPK  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSHPK
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SHPK
DgiDB (Drug Gene Interaction Database)SHPK
DoCM (Curated mutations)SHPK (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SHPK (select a term)
intoGenSHPK
Cancer3DSHPK(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605060   
Orphanet23412   
MedgenSHPK
Genetic Testing Registry SHPK
NextProtQ9UHJ6 [Medical]
TSGene23729
GENETestsSHPK
Huge Navigator SHPK [HugePedia]
snp3D : Map Gene to Disease23729
BioCentury BCIQSHPK
ClinGenSHPK
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD23729
Chemical/Pharm GKB GenePA162403312
Clinical trialSHPK
Miscellaneous
canSAR (ICR)SHPK (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSHPK
EVEXSHPK
GoPubMedSHPK
iHOPSHPK
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 12:43:09 CET 2017

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