SHQ1 (SHQ1, H/ACA ribonucleoprotein assembly factor)

2012-03-01  

Identity

HGNC
SHQ1
LOCATION
3p13
LOCUSID
55164
ALIAS
GRIM-1,Shq1p

Other Information

Locus ID:

NCBI: 55164
MIM: 613663
HGNC: 25543
Ensembl: ENSG00000144736

Variants:

dbSNP: 55164
ClinVar: 55164
TCGA: ENSG00000144736
COSMIC: SHQ1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000144736ENST00000325599Q6PI26
ENSG00000144736ENST00000444040F8WDZ9
ENSG00000144736ENST00000463369Q6PI26
ENSG00000144736ENST00000471526F8WBC6
ENSG00000144736ENST00000482785C9J6N3

Expression (GTEx)

0
5
10
15
Adipose - Subcutaneous
Adipose - Visceral
Adrenal Gland
Artery - Aorta
Artery - Tibial
Bladder
Brain - Amygdala
Brain - Anterior cingulate cortex
Brain - Caudate
Brain - Cerebellar Hemisphere
Brain - Cerebellum
Brain - Cortex
Brain - Frontal Cortex
Brain - Hippocampus
Brain - Hypothalamus
Brain - Nucleus accumbens
Brain - Putamen
Brain - Spinal cord
Brain - Substantia nigra
Breast - Mammary Tissue
Cells - Cultured fibroblasts
Cells - EBV - transformed lymphocytes
Cervix - Ectocervix
Cervix - Endocervix
Colon - Sigmoid
Colon - Transverse
Esophagus - Gastroesophageal Junction
Esophagus - Mucosa
Esophagus - Muscularis
Fallopian Tube
Heart - Atrial Appendage
Heart - Left Ventricle
Kidney - Cortex
Kidney - Medulla
Liver
Lung
Minor Salivary Gland
Muscle - Skeletal
Nerve - Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin - Not Sun Exposed
Skin - Sun Exposed
Small Intestine - Terminal Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole Blood

Protein levels (Protein atlas)

Not detected
Low
Medium
High
cerebral cortex
cerebellum
hippocampus
caudate
thyroid gland
parathyroid gland
adrenal gland
nasopharynx
bronchus
lung
oral mucosa
salivary gland
esophagus
stomach 1
stomach 2
duodenum
small intestine
colon
rectum
liver
gallbladder
pancreas
kidney
urinary bladder
testis
epididymis
seminal vesicle
prostate
vagina
ovary
fallopian tube
endometrium 1
endometrium 2
cervix, uterine
placenta
breast
heart muscle
smooth muscle
skeletal muscle
soft tissue 1
soft tissue 2
adipose tissue
skin 1
skin 2
appendix
spleen
lymph node
tonsil
bone marrow

References

Pubmed IDYearTitleCitations
262882492015Variability of Gene Expression Identifies Transcriptional Regulators of Early Human Embryonic Development.17
219316442011GRIM-1, a novel growth suppressor, inhibits rRNA maturation by suppressing small nucleolar RNAs.6
250815412014Reversed expression of GRIM-1 and GRP78 in human non-small cell lung cancer.5
255538442015Structure and interactions of the CS domain of human H/ACA RNP assembly protein Shq1.5
303231922018SHQ1 regulation of RNA splicing is required for T-lymphoblastic leukemia cell survival.2

Citation

Dessen P

SHQ1 (SHQ1, H/ACA ribonucleoprotein assembly factor)

Atlas Genet Cytogenet Oncol Haematol. 2012-03-01

Online version: http://atlasgeneticsoncology.org/gene/52641/shq1