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SHTN1 (shootin 1)

Identity

Alias_namesKIAA1598
KIAA1598
Alias_symbol (synonym)shootin1
shootin-1
Other alias
HGNC (Hugo) SHTN1
LocusID (NCBI) 57698
Atlas_Id 55059
Location 10q25.3  [Link to chromosome band 10q25]
Location_base_pair Starts at 116883377 and ends at 117005577 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
HSPA12A (10q25.3) / SHTN1 (10q25.3)SHTN1 (10q25.3) / EMX2OS (10q26.11)SHTN1 (10q25.3) / FAM24B (10q26.13)
SHTN1 (10q25.3) / OAT (10q26.13)SHTN1 (10q25.3) / PRDX3 (10q26.11)SHTN1 (10q25.3) / ROS1 (6q22.1)
UBE2D3 (4q24) / SHTN1 (10q25.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SHTN1   29319
Cards
Entrez_Gene (NCBI)SHTN1  57698  shootin 1
AliasesKIAA1598; shootin-1
GeneCards (Weizmann)SHTN1
Ensembl hg19 (Hinxton)ENSG00000187164 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000187164 [Gene_View]  chr10:116883377-117005577 [Contig_View]  SHTN1 [Vega]
ICGC DataPortalENSG00000187164
TCGA cBioPortalSHTN1
AceView (NCBI)SHTN1
Genatlas (Paris)SHTN1
WikiGenes57698
SOURCE (Princeton)SHTN1
Genetics Home Reference (NIH)SHTN1
Genomic and cartography
GoldenPath hg38 (UCSC)SHTN1  -     chr10:116883377-117005577 -  10q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SHTN1  -     10q25.3   [Description]    (hg19-Feb_2009)
EnsemblSHTN1 - 10q25.3 [CytoView hg19]  SHTN1 - 10q25.3 [CytoView hg38]
Mapping of homologs : NCBISHTN1 [Mapview hg19]  SHTN1 [Mapview hg38]
OMIM611171   
Gene and transcription
Genbank (Entrez)AB046818 AK001984 AK091381 AK091410 AK091578
RefSeq transcript (Entrez)NM_001127211 NM_001258298 NM_001258299 NM_001258300 NM_018330
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SHTN1
Cluster EST : UnigeneHs.501140 [ NCBI ]
CGAP (NCI)Hs.501140
Alternative Splicing GalleryENSG00000187164
Gene ExpressionSHTN1 [ NCBI-GEO ]   SHTN1 [ EBI - ARRAY_EXPRESS ]   SHTN1 [ SEEK ]   SHTN1 [ MEM ]
Gene Expression Viewer (FireBrowse)SHTN1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57698
GTEX Portal (Tissue expression)SHTN1
Protein : pattern, domain, 3D structure
UniProt/SwissProtA0MZ66   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA0MZ66  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA0MZ66
Splice isoforms : SwissVarA0MZ66
PhosPhoSitePlusA0MZ66
Domain families : Pfam (Sanger)
Domain families : Pfam (NCBI)
Conserved Domain (NCBI)SHTN1
DMDM Disease mutations57698
Blocks (Seattle)SHTN1
SuperfamilyA0MZ66
Human Protein AtlasENSG00000187164
Peptide AtlasA0MZ66
HPRD11155
IPIIPI00854700   IPI00854567   IPI00448751   IPI00854856   IPI00922178   IPI00921922   IPI00921857   IPI00979766   
Protein Interaction databases
DIP (DOE-UCLA)A0MZ66
IntAct (EBI)A0MZ66
FunCoupENSG00000187164
BioGRIDSHTN1
STRING (EMBL)SHTN1
ZODIACSHTN1
Ontologies - Pathways
QuickGOA0MZ66
Ontology : AmiGOprotein binding  cytoplasm  microtubule  microtubule associated complex  substrate-dependent cell migration, cell extension  Ras protein signal transduction  axonogenesis  microtubule cytoskeleton  kinesin binding  lamellipodium  filopodium  axon  growth cone  cell leading edge  Cdc42 protein signal transduction  netrin-activated signaling pathway  perikaryon  axonal growth cone  cadherin binding  positive regulation of axon extension  perinuclear region of cytoplasm  neuron projection morphogenesis  actin filament binding  cytoplasmic actin-based contraction involved in cell motility  endoplasmic reticulum polarization  actin filament bundle retrograde transport  regulation of establishment of cell polarity  positive regulation of neuron migration  
Ontology : EGO-EBIprotein binding  cytoplasm  microtubule  microtubule associated complex  substrate-dependent cell migration, cell extension  Ras protein signal transduction  axonogenesis  microtubule cytoskeleton  kinesin binding  lamellipodium  filopodium  axon  growth cone  cell leading edge  Cdc42 protein signal transduction  netrin-activated signaling pathway  perikaryon  axonal growth cone  cadherin binding  positive regulation of axon extension  perinuclear region of cytoplasm  neuron projection morphogenesis  actin filament binding  cytoplasmic actin-based contraction involved in cell motility  endoplasmic reticulum polarization  actin filament bundle retrograde transport  regulation of establishment of cell polarity  positive regulation of neuron migration  
NDEx NetworkSHTN1
Atlas of Cancer Signalling NetworkSHTN1
Wikipedia pathwaysSHTN1
Orthology - Evolution
OrthoDB57698
GeneTree (enSembl)ENSG00000187164
Phylogenetic Trees/Animal Genes : TreeFamSHTN1
HOVERGENA0MZ66
HOGENOMA0MZ66
Homologs : HomoloGeneSHTN1
Homology/Alignments : Family Browser (UCSC)SHTN1
Gene fusions - Rearrangements
Fusion : MitelmanHSPA12A/SHTN1 [10q25.3/10q25.3]  [t(10;10)(q25;q25)]  
Fusion : MitelmanSHTN1/EMX2OS [10q25.3/-]  [t(10;10)(q25;q26)]  
Fusion : MitelmanSHTN1/FAM24B [10q25.3/10q26.13]  [t(10;10)(q25;q26)]  
Fusion : MitelmanSHTN1/PRDX3 [10q25.3/10q26.11]  [t(10;10)(q25;q26)]  
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSHTN1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SHTN1
dbVarSHTN1
ClinVarSHTN1
1000_GenomesSHTN1 
Exome Variant ServerSHTN1
ExAC (Exome Aggregation Consortium)SHTN1 (select the gene name)
Genetic variants : HAPMAP57698
Genomic Variants (DGV)SHTN1 [DGVbeta]
DECIPHERSHTN1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSHTN1 
Mutations
ICGC Data PortalSHTN1 
TCGA Data PortalSHTN1 
Broad Tumor PortalSHTN1
OASIS PortalSHTN1 [ Somatic mutations - Copy number]
Mutations and Diseases : HGMDSHTN1
BioMutasearch SHTN1
DgiDB (Drug Gene Interaction Database)SHTN1
DoCM (Curated mutations)SHTN1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SHTN1 (select a term)
intoGenSHTN1
Cancer3DSHTN1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611171   
Orphanet
MedgenSHTN1
Genetic Testing Registry SHTN1
NextProtA0MZ66 [Medical]
TSGene57698
GENETestsSHTN1
Target ValidationSHTN1
Huge Navigator SHTN1 [HugePedia]
snp3D : Map Gene to Disease57698
BioCentury BCIQSHTN1
ClinGenSHTN1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57698
Chemical/Pharm GKB GenePA134973737
Clinical trialSHTN1
Miscellaneous
canSAR (ICR)SHTN1 (select the gene name)
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSHTN1
EVEXSHTN1
GoPubMedSHTN1
iHOPSHTN1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 14:07:16 CEST 2017

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