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SIGLEC1 (sialic acid binding Ig like lectin 1)

Identity

Alias_namesSN
sialoadhesin
sialic acid binding Ig-like lectin 1, sialoadhesin
Alias_symbol (synonym)SIGLEC-1
CD169
FLJ00051
FLJ00055
FLJ00073
FLJ32150
dJ1009E24.1
sialoadhesin
Other alias
HGNC (Hugo) SIGLEC1
LocusID (NCBI) 6614
Atlas_Id 53829
Location 20p13  [Link to chromosome band 20p13]
Location_base_pair Starts at 3667617 and ends at 3687775 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SIGLEC1   11127
Cards
Entrez_Gene (NCBI)SIGLEC1  6614  sialic acid binding Ig like lectin 1
AliasesCD169; SIGLEC-1; SN; dJ1009E24.1
GeneCards (Weizmann)SIGLEC1
Ensembl hg19 (Hinxton)ENSG00000088827 [Gene_View]  chr20:3667617-3687775 [Contig_View]  SIGLEC1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000088827 [Gene_View]  chr20:3667617-3687775 [Contig_View]  SIGLEC1 [Vega]
ICGC DataPortalENSG00000088827
TCGA cBioPortalSIGLEC1
AceView (NCBI)SIGLEC1
Genatlas (Paris)SIGLEC1
WikiGenes6614
SOURCE (Princeton)SIGLEC1
Genetics Home Reference (NIH)SIGLEC1
Genomic and cartography
GoldenPath hg19 (UCSC)SIGLEC1  -     chr20:3667617-3687775 -  20p13   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SIGLEC1  -     20p13   [Description]    (hg38-Dec_2013)
EnsemblSIGLEC1 - 20p13 [CytoView hg19]  SIGLEC1 - 20p13 [CytoView hg38]
Mapping of homologs : NCBISIGLEC1 [Mapview hg19]  SIGLEC1 [Mapview hg38]
OMIM600751   
Gene and transcription
Genbank (Entrez)AF230073 AK024459 AK024462 AK024479 AK057560
RefSeq transcript (Entrez)NM_023068
RefSeq genomic (Entrez)NC_000020 NC_018931 NT_011387 NW_004929416
Consensus coding sequences : CCDS (NCBI)SIGLEC1
Cluster EST : UnigeneHs.31869 [ NCBI ]
CGAP (NCI)Hs.31869
Alternative Splicing GalleryENSG00000088827
Gene ExpressionSIGLEC1 [ NCBI-GEO ]   SIGLEC1 [ EBI - ARRAY_EXPRESS ]   SIGLEC1 [ SEEK ]   SIGLEC1 [ MEM ]
Gene Expression Viewer (FireBrowse)SIGLEC1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6614
GTEX Portal (Tissue expression)SIGLEC1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BZZ2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BZZ2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BZZ2
Splice isoforms : SwissVarQ9BZZ2
PhosPhoSitePlusQ9BZZ2
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)CD80_C2-set    Ig-like_dom    Ig-like_fold    Ig_I-set    Ig_sub    Ig_sub2    Ig_V-set   
Domain families : Pfam (Sanger)C2-set_2 (PF08205)    I-set (PF07679)    Ig_2 (PF13895)    V-set (PF07686)   
Domain families : Pfam (NCBI)pfam08205    pfam07679    pfam13895    pfam07686   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  
Conserved Domain (NCBI)SIGLEC1
DMDM Disease mutations6614
Blocks (Seattle)SIGLEC1
SuperfamilyQ9BZZ2
Human Protein AtlasENSG00000088827
Peptide AtlasQ9BZZ2
HPRD02854
IPIIPI00011961   IPI00219698   IPI00219699   IPI00384766   
Protein Interaction databases
DIP (DOE-UCLA)Q9BZZ2
IntAct (EBI)Q9BZZ2
FunCoupENSG00000088827
BioGRIDSIGLEC1
STRING (EMBL)SIGLEC1
ZODIACSIGLEC1
Ontologies - Pathways
QuickGOQ9BZZ2
Ontology : AmiGOextracellular region  plasma membrane  endocytosis  inflammatory response  cell-matrix adhesion  integral component of membrane  single organismal cell-cell adhesion  carbohydrate binding  
Ontology : EGO-EBIextracellular region  plasma membrane  endocytosis  inflammatory response  cell-matrix adhesion  integral component of membrane  single organismal cell-cell adhesion  carbohydrate binding  
Pathways : KEGGCell adhesion molecules (CAMs)   
NDEx NetworkSIGLEC1
Atlas of Cancer Signalling NetworkSIGLEC1
Wikipedia pathwaysSIGLEC1
Orthology - Evolution
OrthoDB6614
GeneTree (enSembl)ENSG00000088827
Phylogenetic Trees/Animal Genes : TreeFamSIGLEC1
HOVERGENQ9BZZ2
HOGENOMQ9BZZ2
Homologs : HomoloGeneSIGLEC1
Homology/Alignments : Family Browser (UCSC)SIGLEC1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSIGLEC1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SIGLEC1
dbVarSIGLEC1
ClinVarSIGLEC1
1000_GenomesSIGLEC1 
Exome Variant ServerSIGLEC1
ExAC (Exome Aggregation Consortium)SIGLEC1 (select the gene name)
Genetic variants : HAPMAP6614
Genomic Variants (DGV)SIGLEC1 [DGVbeta]
DECIPHER (Syndromes)20:3667617-3687775  ENSG00000088827
CONAN: Copy Number AnalysisSIGLEC1 
Mutations
ICGC Data PortalSIGLEC1 
TCGA Data PortalSIGLEC1 
Broad Tumor PortalSIGLEC1
OASIS PortalSIGLEC1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSIGLEC1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSIGLEC1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SIGLEC1
DgiDB (Drug Gene Interaction Database)SIGLEC1
DoCM (Curated mutations)SIGLEC1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SIGLEC1 (select a term)
intoGenSIGLEC1
Cancer3DSIGLEC1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600751   
Orphanet
MedgenSIGLEC1
Genetic Testing Registry SIGLEC1
NextProtQ9BZZ2 [Medical]
TSGene6614
GENETestsSIGLEC1
Huge Navigator SIGLEC1 [HugePedia]
snp3D : Map Gene to Disease6614
BioCentury BCIQSIGLEC1
ClinGenSIGLEC1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6614
Chemical/Pharm GKB GenePA35976
Clinical trialSIGLEC1
Miscellaneous
canSAR (ICR)SIGLEC1 (select the gene name)
Probes
Litterature
PubMed36 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSIGLEC1
EVEXSIGLEC1
GoPubMedSIGLEC1
iHOPSIGLEC1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:19:16 CEST 2017

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