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SIGLEC10 (sialic acid binding Ig like lectin 10)

Identity

Alias_namessialic acid binding Ig-like lectin 10
Alias_symbol (synonym)SIGLEC-10
SLG2
PRO940
MGC126774
Other alias
HGNC (Hugo) SIGLEC10
LocusID (NCBI) 89790
Atlas_Id 55220
Location 19q13.41  [Link to chromosome band 19q13]
Location_base_pair Starts at 51410021 and ends at 51417803 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
MRPS18C (4q21.23) / SIGLEC10 (19q13.41)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SIGLEC10   15620
Cards
Entrez_Gene (NCBI)SIGLEC10  89790  sialic acid binding Ig like lectin 10
AliasesPRO940; SIGLEC-10; SLG2
GeneCards (Weizmann)SIGLEC10
Ensembl hg19 (Hinxton)ENSG00000142512 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000142512 [Gene_View]  ENSG00000142512 [Sequence]  chr19:51410021-51417803 [Contig_View]  SIGLEC10 [Vega]
ICGC DataPortalENSG00000142512
TCGA cBioPortalSIGLEC10
AceView (NCBI)SIGLEC10
Genatlas (Paris)SIGLEC10
WikiGenes89790
SOURCE (Princeton)SIGLEC10
Genetics Home Reference (NIH)SIGLEC10
Genomic and cartography
GoldenPath hg38 (UCSC)SIGLEC10  -     chr19:51410021-51417803 -  19q13.41   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SIGLEC10  -     19q13.41   [Description]    (hg19-Feb_2009)
EnsemblSIGLEC10 - 19q13.41 [CytoView hg19]  SIGLEC10 - 19q13.41 [CytoView hg38]
Mapping of homologs : NCBISIGLEC10 [Mapview hg19]  SIGLEC10 [Mapview hg38]
OMIM606091   
Gene and transcription
Genbank (Entrez)AF301007 AF310233 AF311905 AK122619 AK289900
RefSeq transcript (Entrez)NM_001171156 NM_001171157 NM_001171158 NM_001171159 NM_001171160 NM_001171161 NM_001322105 NM_033130
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SIGLEC10
Cluster EST : UnigeneHs.284813 [ NCBI ]
CGAP (NCI)Hs.284813
Alternative Splicing GalleryENSG00000142512
Gene ExpressionSIGLEC10 [ NCBI-GEO ]   SIGLEC10 [ EBI - ARRAY_EXPRESS ]   SIGLEC10 [ SEEK ]   SIGLEC10 [ MEM ]
Gene Expression Viewer (FireBrowse)SIGLEC10 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)89790
GTEX Portal (Tissue expression)SIGLEC10
Human Protein AtlasENSG00000142512-SIGLEC10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96LC7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96LC7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96LC7
Splice isoforms : SwissVarQ96LC7
PhosPhoSitePlusQ96LC7
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    IG_MHC (PS00290)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_dom_sf    Ig-like_fold    Ig/MHC_CS    Ig_sub    Ig_sub2    Ig_V-set   
Domain families : Pfam (Sanger)Ig_2 (PF13895)    V-set (PF07686)   
Domain families : Pfam (NCBI)pfam13895    pfam07686   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  
Conserved Domain (NCBI)SIGLEC10
DMDM Disease mutations89790
Blocks (Seattle)SIGLEC10
SuperfamilyQ96LC7
Human Protein Atlas [tissue]ENSG00000142512-SIGLEC10 [tissue]
Peptide AtlasQ96LC7
HPRD07307
IPIIPI00064982   IPI00219603   IPI00219605   IPI00219606   IPI00219608   IPI00432569   IPI00954826   IPI00984584   IPI00939867   IPI00975820   IPI00983861   
Protein Interaction databases
DIP (DOE-UCLA)Q96LC7
IntAct (EBI)Q96LC7
FunCoupENSG00000142512
BioGRIDSIGLEC10
STRING (EMBL)SIGLEC10
ZODIACSIGLEC10
Ontologies - Pathways
QuickGOQ96LC7
Ontology : AmiGOadaptive immune response  protein binding  extracellular region  plasma membrane  cell adhesion  integral component of membrane  phosphatase binding  carbohydrate binding  SH2 domain binding  innate immune response  negative regulation of inflammatory response to wounding  
Ontology : EGO-EBIadaptive immune response  protein binding  extracellular region  plasma membrane  cell adhesion  integral component of membrane  phosphatase binding  carbohydrate binding  SH2 domain binding  innate immune response  negative regulation of inflammatory response to wounding  
NDEx NetworkSIGLEC10
Atlas of Cancer Signalling NetworkSIGLEC10
Wikipedia pathwaysSIGLEC10
Orthology - Evolution
OrthoDB89790
GeneTree (enSembl)ENSG00000142512
Phylogenetic Trees/Animal Genes : TreeFamSIGLEC10
HOGENOMQ96LC7
Homologs : HomoloGeneSIGLEC10
Homology/Alignments : Family Browser (UCSC)SIGLEC10
Gene fusions - Rearrangements
Fusion : QuiverSIGLEC10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSIGLEC10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SIGLEC10
dbVarSIGLEC10
ClinVarSIGLEC10
1000_GenomesSIGLEC10 
Exome Variant ServerSIGLEC10
ExAC (Exome Aggregation Consortium)ENSG00000142512
GNOMAD BrowserENSG00000142512
Varsome BrowserSIGLEC10
Genetic variants : HAPMAP89790
Genomic Variants (DGV)SIGLEC10 [DGVbeta]
DECIPHERSIGLEC10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSIGLEC10 
Mutations
ICGC Data PortalSIGLEC10 
TCGA Data PortalSIGLEC10 
Broad Tumor PortalSIGLEC10
OASIS PortalSIGLEC10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSIGLEC10  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSIGLEC10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SIGLEC10
DgiDB (Drug Gene Interaction Database)SIGLEC10
DoCM (Curated mutations)SIGLEC10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SIGLEC10 (select a term)
intoGenSIGLEC10
Cancer3DSIGLEC10(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM606091   
Orphanet
DisGeNETSIGLEC10
MedgenSIGLEC10
Genetic Testing Registry SIGLEC10
NextProtQ96LC7 [Medical]
TSGene89790
GENETestsSIGLEC10
Target ValidationSIGLEC10
Huge Navigator SIGLEC10 [HugePedia]
snp3D : Map Gene to Disease89790
BioCentury BCIQSIGLEC10
ClinGenSIGLEC10
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD89790
Chemical/Pharm GKB GenePA38004
Clinical trialSIGLEC10
Miscellaneous
canSAR (ICR)SIGLEC10 (select the gene name)
Probes
Litterature
PubMed17 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSIGLEC10
EVEXSIGLEC10
GoPubMedSIGLEC10
iHOPSIGLEC10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Dec 21 15:51:22 CET 2018

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