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SIGLEC15 (sialic acid binding Ig like lectin 15)

Identity

Alias_namesCD33L3
CD33 antigen-like 3
CD33 molecule-like 3
sialic acid binding Ig-like lectin 15
Alias_symbol (synonym)HsT1361
Other aliasSIGLEC-15
HGNC (Hugo) SIGLEC15
LocusID (NCBI) 284266
Atlas_Id 53430
Location 18q12.3  [Link to chromosome band 18q12]
Location_base_pair Starts at 43405545 and ends at 43422521 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SIGLEC15   27596
Cards
Entrez_Gene (NCBI)SIGLEC15  284266  sialic acid binding Ig like lectin 15
AliasesCD33L3; HsT1361; SIGLEC-15
GeneCards (Weizmann)SIGLEC15
Ensembl hg19 (Hinxton)ENSG00000197046 [Gene_View]  chr18:43405545-43422521 [Contig_View]  SIGLEC15 [Vega]
Ensembl hg38 (Hinxton)ENSG00000197046 [Gene_View]  chr18:43405545-43422521 [Contig_View]  SIGLEC15 [Vega]
ICGC DataPortalENSG00000197046
TCGA cBioPortalSIGLEC15
AceView (NCBI)SIGLEC15
Genatlas (Paris)SIGLEC15
WikiGenes284266
SOURCE (Princeton)SIGLEC15
Genetics Home Reference (NIH)SIGLEC15
Genomic and cartography
GoldenPath hg19 (UCSC)SIGLEC15  -     chr18:43405545-43422521 +  18q12.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SIGLEC15  -     18q12.3   [Description]    (hg38-Dec_2013)
EnsemblSIGLEC15 - 18q12.3 [CytoView hg19]  SIGLEC15 - 18q12.3 [CytoView hg38]
Mapping of homologs : NCBISIGLEC15 [Mapview hg19]  SIGLEC15 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK025833 AK092746 AK095432 AK172835 AK290400
RefSeq transcript (Entrez)NM_213602
RefSeq genomic (Entrez)NC_000018 NC_018929 NT_010966 NW_004929410
Consensus coding sequences : CCDS (NCBI)SIGLEC15
Cluster EST : UnigeneHs.287692 [ NCBI ]
CGAP (NCI)Hs.287692
Alternative Splicing GalleryENSG00000197046
Gene ExpressionSIGLEC15 [ NCBI-GEO ]   SIGLEC15 [ EBI - ARRAY_EXPRESS ]   SIGLEC15 [ SEEK ]   SIGLEC15 [ MEM ]
Gene Expression Viewer (FireBrowse)SIGLEC15 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)284266
GTEX Portal (Tissue expression)SIGLEC15
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ6ZMC9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ6ZMC9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ6ZMC9
Splice isoforms : SwissVarQ6ZMC9
PhosPhoSitePlusQ6ZMC9
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_sub    Ig_V-set   
Domain families : Pfam (Sanger)V-set (PF07686)   
Domain families : Pfam (NCBI)pfam07686   
Domain families : Smart (EMBL)IG (SM00409)  
Conserved Domain (NCBI)SIGLEC15
DMDM Disease mutations284266
Blocks (Seattle)SIGLEC15
SuperfamilyQ6ZMC9
Human Protein AtlasENSG00000197046
Peptide AtlasQ6ZMC9
HPRD13011
IPIIPI00796217   IPI00911036   
Protein Interaction databases
DIP (DOE-UCLA)Q6ZMC9
IntAct (EBI)Q6ZMC9
FunCoupENSG00000197046
BioGRIDSIGLEC15
STRING (EMBL)SIGLEC15
ZODIACSIGLEC15
Ontologies - Pathways
QuickGOQ6ZMC9
Ontology : AmiGOplasma membrane  integral component of membrane  regulation of actin cytoskeleton organization  protein complex  innate immune response  regulation of bone resorption  cellular response to lipoprotein particle stimulus  regulation of osteoclast development  
Ontology : EGO-EBIplasma membrane  integral component of membrane  regulation of actin cytoskeleton organization  protein complex  innate immune response  regulation of bone resorption  cellular response to lipoprotein particle stimulus  regulation of osteoclast development  
NDEx NetworkSIGLEC15
Atlas of Cancer Signalling NetworkSIGLEC15
Wikipedia pathwaysSIGLEC15
Orthology - Evolution
OrthoDB284266
GeneTree (enSembl)ENSG00000197046
Phylogenetic Trees/Animal Genes : TreeFamSIGLEC15
HOVERGENQ6ZMC9
HOGENOMQ6ZMC9
Homologs : HomoloGeneSIGLEC15
Homology/Alignments : Family Browser (UCSC)SIGLEC15
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSIGLEC15 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SIGLEC15
dbVarSIGLEC15
ClinVarSIGLEC15
1000_GenomesSIGLEC15 
Exome Variant ServerSIGLEC15
ExAC (Exome Aggregation Consortium)SIGLEC15 (select the gene name)
Genetic variants : HAPMAP284266
Genomic Variants (DGV)SIGLEC15 [DGVbeta]
DECIPHER (Syndromes)18:43405545-43422521  ENSG00000197046
CONAN: Copy Number AnalysisSIGLEC15 
Mutations
ICGC Data PortalSIGLEC15 
TCGA Data PortalSIGLEC15 
Broad Tumor PortalSIGLEC15
OASIS PortalSIGLEC15 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSIGLEC15  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSIGLEC15
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SIGLEC15
DgiDB (Drug Gene Interaction Database)SIGLEC15
DoCM (Curated mutations)SIGLEC15 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SIGLEC15 (select a term)
intoGenSIGLEC15
Cancer3DSIGLEC15(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenSIGLEC15
Genetic Testing Registry SIGLEC15
NextProtQ6ZMC9 [Medical]
TSGene284266
GENETestsSIGLEC15
Huge Navigator SIGLEC15 [HugePedia]
snp3D : Map Gene to Disease284266
BioCentury BCIQSIGLEC15
ClinGenSIGLEC15
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD284266
Chemical/Pharm GKB GenePA162403350
Clinical trialSIGLEC15
Miscellaneous
canSAR (ICR)SIGLEC15 (select the gene name)
Probes
Litterature
PubMed3 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSIGLEC15
EVEXSIGLEC15
GoPubMedSIGLEC15
iHOPSIGLEC15
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Mar 14 13:27:16 CET 2017

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