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SIGLEC6 (sialic acid binding Ig like lectin 6)

Identity

Alias_namesCD33L
CD33L1
sialic acid binding Ig-like lectin 6
Alias_symbol (synonym)OB-BP1
SIGLEC-6
CD327
Other aliasCD33L2
CDW327
OBBP1
HGNC (Hugo) SIGLEC6
LocusID (NCBI) 946
Atlas_Id 56555
Location 19q13.41  [Link to chromosome band 19q13]
Location_base_pair Starts at 51517819 and ends at 51531856 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SIGLEC6   10875
Cards
Entrez_Gene (NCBI)SIGLEC6  946  sialic acid binding Ig like lectin 6
AliasesCD327; CD33L; CD33L1; CD33L2; 
CDW327; OBBP1
GeneCards (Weizmann)SIGLEC6
Ensembl hg19 (Hinxton)ENSG00000105492 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000105492 [Gene_View]  chr19:51517819-51531856 [Contig_View]  SIGLEC6 [Vega]
ICGC DataPortalENSG00000105492
TCGA cBioPortalSIGLEC6
AceView (NCBI)SIGLEC6
Genatlas (Paris)SIGLEC6
WikiGenes946
SOURCE (Princeton)SIGLEC6
Genetics Home Reference (NIH)SIGLEC6
Genomic and cartography
GoldenPath hg38 (UCSC)SIGLEC6  -     chr19:51517819-51531856 -  19q13.41   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SIGLEC6  -     19q13.41   [Description]    (hg19-Feb_2009)
EnsemblSIGLEC6 - 19q13.41 [CytoView hg19]  SIGLEC6 - 19q13.41 [CytoView hg38]
Mapping of homologs : NCBISIGLEC6 [Mapview hg19]  SIGLEC6 [Mapview hg38]
OMIM604405   
Gene and transcription
Genbank (Entrez)AK300170 AK300182 AK308174 AK309903 AU138048
RefSeq transcript (Entrez)NM_001177547 NM_001177548 NM_001177549 NM_001245 NM_198845 NM_198846
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SIGLEC6
Cluster EST : UnigeneHs.720304 [ NCBI ]
CGAP (NCI)Hs.720304
Alternative Splicing GalleryENSG00000105492
Gene ExpressionSIGLEC6 [ NCBI-GEO ]   SIGLEC6 [ EBI - ARRAY_EXPRESS ]   SIGLEC6 [ SEEK ]   SIGLEC6 [ MEM ]
Gene Expression Viewer (FireBrowse)SIGLEC6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)946
GTEX Portal (Tissue expression)SIGLEC6
Protein : pattern, domain, 3D structure
UniProt/SwissProtO43699   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO43699  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO43699
Splice isoforms : SwissVarO43699
PhosPhoSitePlusO43699
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)    IG_MHC (PS00290)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig/MHC_CS    Ig_I-set    Ig_sub    Ig_sub2    Ig_V-set    Immunoglobulin   
Domain families : Pfam (Sanger)I-set (PF07679)    ig (PF00047)    V-set (PF07686)   
Domain families : Pfam (NCBI)pfam07679    pfam00047    pfam07686   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  
Conserved Domain (NCBI)SIGLEC6
DMDM Disease mutations946
Blocks (Seattle)SIGLEC6
SuperfamilyO43699
Human Protein AtlasENSG00000105492
Peptide AtlasO43699
HPRD16058
IPIIPI00789490   IPI00791311   IPI00394840   IPI00914997   IPI00927323   IPI00924914   
Protein Interaction databases
DIP (DOE-UCLA)O43699
IntAct (EBI)O43699
FunCoupENSG00000105492
BioGRIDSIGLEC6
STRING (EMBL)SIGLEC6
ZODIACSIGLEC6
Ontologies - Pathways
QuickGOO43699
Ontology : AmiGOprotein binding  extracellular region  integral component of plasma membrane  cell adhesion  cell-cell signaling  membrane  carbohydrate binding  
Ontology : EGO-EBIprotein binding  extracellular region  integral component of plasma membrane  cell adhesion  cell-cell signaling  membrane  carbohydrate binding  
NDEx NetworkSIGLEC6
Atlas of Cancer Signalling NetworkSIGLEC6
Wikipedia pathwaysSIGLEC6
Orthology - Evolution
OrthoDB946
GeneTree (enSembl)ENSG00000105492
Phylogenetic Trees/Animal Genes : TreeFamSIGLEC6
HOVERGENO43699
HOGENOMO43699
Homologs : HomoloGeneSIGLEC6
Homology/Alignments : Family Browser (UCSC)SIGLEC6
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSIGLEC6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SIGLEC6
dbVarSIGLEC6
ClinVarSIGLEC6
1000_GenomesSIGLEC6 
Exome Variant ServerSIGLEC6
ExAC (Exome Aggregation Consortium)SIGLEC6 (select the gene name)
Genetic variants : HAPMAP946
Genomic Variants (DGV)SIGLEC6 [DGVbeta]
DECIPHERSIGLEC6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSIGLEC6 
Mutations
ICGC Data PortalSIGLEC6 
TCGA Data PortalSIGLEC6 
Broad Tumor PortalSIGLEC6
OASIS PortalSIGLEC6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSIGLEC6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSIGLEC6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SIGLEC6
DgiDB (Drug Gene Interaction Database)SIGLEC6
DoCM (Curated mutations)SIGLEC6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SIGLEC6 (select a term)
intoGenSIGLEC6
Cancer3DSIGLEC6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604405   
Orphanet
MedgenSIGLEC6
Genetic Testing Registry SIGLEC6
NextProtO43699 [Medical]
TSGene946
GENETestsSIGLEC6
Target ValidationSIGLEC6
Huge Navigator SIGLEC6 [HugePedia]
snp3D : Map Gene to Disease946
BioCentury BCIQSIGLEC6
ClinGenSIGLEC6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD946
Chemical/Pharm GKB GenePA35776
Clinical trialSIGLEC6
Miscellaneous
canSAR (ICR)SIGLEC6 (select the gene name)
Probes
Litterature
PubMed14 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSIGLEC6
EVEXSIGLEC6
GoPubMedSIGLEC6
iHOPSIGLEC6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:14:29 CEST 2017

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