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SIGLEC7 (sialic acid binding Ig like lectin 7)

Identity

Alias_namesSIGLEC19P
SIGLECP2
sialic acid binding Ig-like lectin 19, pseudogene
sialic acid binding Ig-like lectin, pseudogene 2
sialic acid binding Ig-like lectin 7
Alias_symbol (synonym)SIGLEC-7
p75/AIRM1
QA79
CD328
Other aliasAIRM1
CDw328
D-siglec
p75
HGNC (Hugo) SIGLEC7
LocusID (NCBI) 27036
Atlas_Id 45703
Location 19q13.41  [Link to chromosome band 19q13]
Location_base_pair Starts at 51142301 and ends at 51153526 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SIGLEC7   10876
Cards
Entrez_Gene (NCBI)SIGLEC7  27036  sialic acid binding Ig like lectin 7
AliasesAIRM1; CD328; CDw328; D-siglec; 
QA79; SIGLEC-7; SIGLEC19P; SIGLECP2; p75; p75/AIRM1
GeneCards (Weizmann)SIGLEC7
Ensembl hg19 (Hinxton)ENSG00000168995 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000168995 [Gene_View]  chr19:51142301-51153526 [Contig_View]  SIGLEC7 [Vega]
ICGC DataPortalENSG00000168995
TCGA cBioPortalSIGLEC7
AceView (NCBI)SIGLEC7
Genatlas (Paris)SIGLEC7
WikiGenes27036
SOURCE (Princeton)SIGLEC7
Genetics Home Reference (NIH)SIGLEC7
Genomic and cartography
GoldenPath hg38 (UCSC)SIGLEC7  -     chr19:51142301-51153526 +  19q13.41   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SIGLEC7  -     19q13.41   [Description]    (hg19-Feb_2009)
EnsemblSIGLEC7 - 19q13.41 [CytoView hg19]  SIGLEC7 - 19q13.41 [CytoView hg38]
Mapping of homologs : NCBISIGLEC7 [Mapview hg19]  SIGLEC7 [Mapview hg38]
OMIM604410   
Gene and transcription
Genbank (Entrez)AF170485 AF178981 AF193441 AJ007395 AJ130710
RefSeq transcript (Entrez)NM_001277201 NM_014385 NM_016543
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SIGLEC7
Cluster EST : UnigeneHs.655393 [ NCBI ]
CGAP (NCI)Hs.655393
Alternative Splicing GalleryENSG00000168995
Gene ExpressionSIGLEC7 [ NCBI-GEO ]   SIGLEC7 [ EBI - ARRAY_EXPRESS ]   SIGLEC7 [ SEEK ]   SIGLEC7 [ MEM ]
Gene Expression Viewer (FireBrowse)SIGLEC7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)27036
GTEX Portal (Tissue expression)SIGLEC7
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9Y286   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9Y286  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9Y286
Splice isoforms : SwissVarQ9Y286
PhosPhoSitePlusQ9Y286
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_sub    Ig_sub2    Ig_V-set   
Domain families : Pfam (Sanger)Ig_2 (PF13895)    V-set (PF07686)   
Domain families : Pfam (NCBI)pfam13895    pfam07686   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  
Conserved Domain (NCBI)SIGLEC7
DMDM Disease mutations27036
Blocks (Seattle)SIGLEC7
PDB (SRS)1NKO    1O7S    1O7V    2DF3    2G5R    2HRL   
PDB (PDBSum)1NKO    1O7S    1O7V    2DF3    2G5R    2HRL   
PDB (IMB)1NKO    1O7S    1O7V    2DF3    2G5R    2HRL   
PDB (RSDB)1NKO    1O7S    1O7V    2DF3    2G5R    2HRL   
Structural Biology KnowledgeBase1NKO    1O7S    1O7V    2DF3    2G5R    2HRL   
SCOP (Structural Classification of Proteins)1NKO    1O7S    1O7V    2DF3    2G5R    2HRL   
CATH (Classification of proteins structures)1NKO    1O7S    1O7V    2DF3    2G5R    2HRL   
SuperfamilyQ9Y286
Human Protein AtlasENSG00000168995
Peptide AtlasQ9Y286
HPRD05102
IPIIPI00004288   IPI00220858   IPI00220860   IPI00220862   
Protein Interaction databases
DIP (DOE-UCLA)Q9Y286
IntAct (EBI)Q9Y286
FunCoupENSG00000168995
BioGRIDSIGLEC7
STRING (EMBL)SIGLEC7
ZODIACSIGLEC7
Ontologies - Pathways
QuickGOQ9Y286
Ontology : AmiGOreceptor activity  plasma membrane  integral component of plasma membrane  cell adhesion  carbohydrate binding  regulation of immune response  
Ontology : EGO-EBIreceptor activity  plasma membrane  integral component of plasma membrane  cell adhesion  carbohydrate binding  regulation of immune response  
NDEx NetworkSIGLEC7
Atlas of Cancer Signalling NetworkSIGLEC7
Wikipedia pathwaysSIGLEC7
Orthology - Evolution
OrthoDB27036
GeneTree (enSembl)ENSG00000168995
Phylogenetic Trees/Animal Genes : TreeFamSIGLEC7
HOVERGENQ9Y286
HOGENOMQ9Y286
Homologs : HomoloGeneSIGLEC7
Homology/Alignments : Family Browser (UCSC)SIGLEC7
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSIGLEC7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SIGLEC7
dbVarSIGLEC7
ClinVarSIGLEC7
1000_GenomesSIGLEC7 
Exome Variant ServerSIGLEC7
ExAC (Exome Aggregation Consortium)SIGLEC7 (select the gene name)
Genetic variants : HAPMAP27036
Genomic Variants (DGV)SIGLEC7 [DGVbeta]
DECIPHERSIGLEC7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSIGLEC7 
Mutations
ICGC Data PortalSIGLEC7 
TCGA Data PortalSIGLEC7 
Broad Tumor PortalSIGLEC7
OASIS PortalSIGLEC7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSIGLEC7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSIGLEC7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SIGLEC7
DgiDB (Drug Gene Interaction Database)SIGLEC7
DoCM (Curated mutations)SIGLEC7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SIGLEC7 (select a term)
intoGenSIGLEC7
Cancer3DSIGLEC7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604410   
Orphanet
MedgenSIGLEC7
Genetic Testing Registry SIGLEC7
NextProtQ9Y286 [Medical]
TSGene27036
GENETestsSIGLEC7
Target ValidationSIGLEC7
Huge Navigator SIGLEC7 [HugePedia]
snp3D : Map Gene to Disease27036
BioCentury BCIQSIGLEC7
ClinGenSIGLEC7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD27036
Chemical/Pharm GKB GenePA35777
Clinical trialSIGLEC7
Miscellaneous
canSAR (ICR)SIGLEC7 (select the gene name)
Probes
Litterature
PubMed31 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSIGLEC7
EVEXSIGLEC7
GoPubMedSIGLEC7
iHOPSIGLEC7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed Jun 7 12:55:30 CEST 2017

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