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SIKE1 (suppressor of IKBKE 1)

Identity

Alias_symbol (synonym)FLJ21168
SIKE
Other alias
HGNC (Hugo) SIKE1
LocusID (NCBI) 80143
Atlas_Id 73251
Location 1p13.2  [Link to chromosome band 1p13]
Location_base_pair Starts at 114769484 and ends at 114780687 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)		RBM3 (Xp11.23) / SIKE1 (1p13.2)SIKE1 (1p13.2) / SIKE1 (1p13.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SIKE1   26119
Cards
Entrez_Gene (NCBI)SIKE1  80143  suppressor of IKBKE 1
AliasesSIKE
GeneCards (Weizmann)SIKE1
Ensembl hg19 (Hinxton)ENSG00000052723 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000052723 [Gene_View]  chr1:114769484-114780687 [Contig_View]  SIKE1 [Vega]
ICGC DataPortalENSG00000052723
TCGA cBioPortalSIKE1
AceView (NCBI)SIKE1
Genatlas (Paris)SIKE1
WikiGenes80143
SOURCE (Princeton)SIKE1
Genetics Home Reference (NIH)SIKE1
Genomic and cartography
GoldenPath hg38 (UCSC)SIKE1  -     chr1:114769484-114780687 -  1p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SIKE1  -     1p13.2   [Description]    (hg19-Feb_2009)
EnsemblSIKE1 - 1p13.2 [CytoView hg19]  SIKE1 - 1p13.2 [CytoView hg38]
Mapping of homologs : NCBISIKE1 [Mapview hg19]  SIKE1 [Mapview hg38]
OMIM611656   
Gene and transcription
Genbank (Entrez)AI039175 AI221103 AK024821 AK126316 AK225734
RefSeq transcript (Entrez)NM_001102396 NM_025073
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SIKE1
Cluster EST : UnigeneHs.709277 [ NCBI ]
CGAP (NCI)Hs.709277
Alternative Splicing GalleryENSG00000052723
Gene ExpressionSIKE1 [ NCBI-GEO ]   SIKE1 [ EBI - ARRAY_EXPRESS ]   SIKE1 [ SEEK ]   SIKE1 [ MEM ]
Gene Expression Viewer (FireBrowse)SIKE1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)80143
GTEX Portal (Tissue expression)SIKE1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BRV8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BRV8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BRV8
Splice isoforms : SwissVarQ9BRV8
PhosPhoSitePlusQ9BRV8
Domains : Interpro (EBI)SIKE   
Domain families : Pfam (Sanger)DUF837 (PF05769)   
Domain families : Pfam (NCBI)pfam05769   
Conserved Domain (NCBI)SIKE1
DMDM Disease mutations80143
Blocks (Seattle)SIKE1
SuperfamilyQ9BRV8
Human Protein AtlasENSG00000052723
Peptide AtlasQ9BRV8
HPRD07958
IPIIPI00640464   IPI00305186   
Protein Interaction databases
DIP (DOE-UCLA)Q9BRV8
IntAct (EBI)Q9BRV8
FunCoupENSG00000052723
BioGRIDSIKE1
STRING (EMBL)SIKE1
ZODIACSIKE1
Ontologies - Pathways
QuickGOQ9BRV8
Ontology : AmiGOprotein binding  cytosol  
Ontology : EGO-EBIprotein binding  cytosol  
Pathways : KEGGRIG-I-like receptor signaling pathway   
NDEx NetworkSIKE1
Atlas of Cancer Signalling NetworkSIKE1
Wikipedia pathwaysSIKE1
Orthology - Evolution
OrthoDB80143
GeneTree (enSembl)ENSG00000052723
Phylogenetic Trees/Animal Genes : TreeFamSIKE1
HOVERGENQ9BRV8
HOGENOMQ9BRV8
Homologs : HomoloGeneSIKE1
Homology/Alignments : Family Browser (UCSC)SIKE1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSIKE1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SIKE1
dbVarSIKE1
ClinVarSIKE1
1000_GenomesSIKE1 
Exome Variant ServerSIKE1
ExAC (Exome Aggregation Consortium)SIKE1 (select the gene name)
Genetic variants : HAPMAP80143
Genomic Variants (DGV)SIKE1 [DGVbeta]
DECIPHERSIKE1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSIKE1 
Mutations
ICGC Data PortalSIKE1 
TCGA Data PortalSIKE1 
Broad Tumor PortalSIKE1
OASIS PortalSIKE1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSIKE1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSIKE1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SIKE1
DgiDB (Drug Gene Interaction Database)SIKE1
DoCM (Curated mutations)SIKE1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SIKE1 (select a term)
intoGenSIKE1
Cancer3DSIKE1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611656   
Orphanet
MedgenSIKE1
Genetic Testing Registry SIKE1
NextProtQ9BRV8 [Medical]
TSGene80143
GENETestsSIKE1
Target ValidationSIKE1
Huge Navigator SIKE1 [HugePedia]
snp3D : Map Gene to Disease80143
BioCentury BCIQSIKE1
ClinGenSIKE1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD80143
Chemical/Pharm GKB GenePA165752371
Clinical trialSIKE1
Miscellaneous
canSAR (ICR)SIKE1 (select the gene name)
Probes
Litterature
PubMed15 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSIKE1
EVEXSIKE1
GoPubMedSIKE1
iHOPSIKE1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Wed May 31 15:40:46 CEST 2017
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