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SINHCAF (SIN3-HDAC complex associated factor)

Identity

Alias (NCBI)C12orf14
FAM60A
L4
TERA
HGNC (Hugo) SINHCAF
HGNC Alias symbTERA
HGNC Previous nameC12orf14
 FAM60A
HGNC Previous namechromosome 12 open reading frame 14
 family with sequence similarity 60, member A
LocusID (NCBI) 58516
Atlas_Id 57061
Location 12p11.21  [Link to chromosome band 12p11]
Location_base_pair Starts at 31280586 and ends at 31326187 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute



Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(12;17)(p11;q25) SINHCAF/SEPT9


External links

 

Nomenclature
HGNC (Hugo)SINHCAF   30702
Cards
Entrez_Gene (NCBI)SINHCAF    SIN3-HDAC complex associated factor
AliasesC12orf14; FAM60A; L4; TERA
GeneCards (Weizmann)SINHCAF
Ensembl hg19 (Hinxton)ENSG00000139146 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000139146 [Gene_View]  ENSG00000139146 [Sequence]  chr12:31280586-31326187 [Contig_View]  SINHCAF [Vega]
ICGC DataPortalENSG00000139146
TCGA cBioPortalSINHCAF
AceView (NCBI)SINHCAF
Genatlas (Paris)SINHCAF
SOURCE (Princeton)SINHCAF
Genetics Home Reference (NIH)SINHCAF
Genomic and cartography
GoldenPath hg38 (UCSC)SINHCAF  -     chr12:31280586-31326187 -  12p11.21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SINHCAF  -     12p11.21   [Description]    (hg19-Feb_2009)
GoldenPathSINHCAF - 12p11.21 [CytoView hg19]  SINHCAF - 12p11.21 [CytoView hg38]
ImmunoBaseENSG00000139146
Genome Data Viewer NCBISINHCAF [Mapview hg19]  
OMIM615027   
Gene and transcription
Genbank (Entrez)AF087885 AF212220 AK026932 AK027736 AK294457
RefSeq transcript (Entrez)NM_001135811 NM_001135812 NM_021238
Consensus coding sequences : CCDS (NCBI)SINHCAF
Gene ExpressionSINHCAF [ NCBI-GEO ]   SINHCAF [ EBI - ARRAY_EXPRESS ]   SINHCAF [ SEEK ]   SINHCAF [ MEM ]
Gene Expression Viewer (FireBrowse)SINHCAF [ Firebrowse - Broad ]
GenevisibleExpression of SINHCAF in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)58516
GTEX Portal (Tissue expression)SINHCAF
Human Protein AtlasENSG00000139146-SINHCAF [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NP50   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9NP50  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9NP50
PhosPhoSitePlusQ9NP50
Domains : Interpro (EBI)FAM60A   
Domain families : Pfam (Sanger)FAM60A (PF15396)   
Domain families : Pfam (NCBI)pfam15396   
Conserved Domain (NCBI)SINHCAF
SuperfamilyQ9NP50
AlphaFold pdb e-kbQ9NP50   
Human Protein Atlas [tissue]ENSG00000139146-SINHCAF [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q9NP50
IntAct (EBI)Q9NP50
BioGRIDSINHCAF
STRING (EMBL)SINHCAF
ZODIACSINHCAF
Ontologies - Pathways
QuickGOQ9NP50
Ontology : AmiGOprotein binding  positive regulation of cell population proliferation  Sin3 complex  Sin3 complex  negative regulation of cell migration  negative regulation of cell migration  negative regulation of cell differentiation  
Ontology : EGO-EBIprotein binding  positive regulation of cell population proliferation  Sin3 complex  Sin3 complex  negative regulation of cell migration  negative regulation of cell migration  negative regulation of cell differentiation  
NDEx NetworkSINHCAF
Atlas of Cancer Signalling NetworkSINHCAF
Wikipedia pathwaysSINHCAF
Orthology - Evolution
OrthoDB58516
GeneTree (enSembl)ENSG00000139146
Phylogenetic Trees/Animal Genes : TreeFamSINHCAF
Homologs : HomoloGeneSINHCAF
Homology/Alignments : Family Browser (UCSC)SINHCAF
Gene fusions - Rearrangements
Fusion : QuiverSINHCAF
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSINHCAF [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SINHCAF
dbVarSINHCAF
ClinVarSINHCAF
MonarchSINHCAF
1000_GenomesSINHCAF 
Exome Variant ServerSINHCAF
GNOMAD BrowserENSG00000139146
Varsome BrowserSINHCAF
ACMGSINHCAF variants
VarityQ9NP50
Genomic Variants (DGV)SINHCAF [DGVbeta]
DECIPHERSINHCAF [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSINHCAF 
Mutations
ICGC Data PortalSINHCAF 
TCGA Data PortalSINHCAF 
Broad Tumor PortalSINHCAF
OASIS PortalSINHCAF [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSINHCAF  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSINHCAF
Mutations and Diseases : HGMDSINHCAF
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSINHCAF
DgiDB (Drug Gene Interaction Database)SINHCAF
DoCM (Curated mutations)SINHCAF
CIViC (Clinical Interpretations of Variants in Cancer)SINHCAF
Cancer3DSINHCAF
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM615027   
Orphanet
DisGeNETSINHCAF
MedgenSINHCAF
Genetic Testing Registry SINHCAF
NextProtQ9NP50 [Medical]
GENETestsSINHCAF
Target ValidationSINHCAF
Huge Navigator SINHCAF [HugePedia]
ClinGenSINHCAF
Clinical trials, drugs, therapy
MyCancerGenomeSINHCAF
Protein Interactions : CTDSINHCAF
Pharm GKB GenePA134921007
PharosQ9NP50
Clinical trialSINHCAF
Miscellaneous
canSAR (ICR)SINHCAF
HarmonizomeSINHCAF
DataMed IndexSINHCAF
Probes
Litterature
PubMed37 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSINHCAF
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:31:12 CEST 2021

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