SIRPB1 (signal regulatory protein beta 1)

2003-05-01  

Identity

HGNC
LOCATION
20p13
LOCUSID
ALIAS
CD172b,SIRP-BETA-1

Other Information

Locus ID:

NCBI: 10326
MIM: 603889
HGNC: 15928
Ensembl: ENSG00000101307

Variants:

dbSNP: 10326
ClinVar: 10326
TCGA: ENSG00000101307
COSMIC: SIRPB1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000101307ENST00000262929H9KV29
ENSG00000101307ENST00000279477Q5TFQ8
ENSG00000101307ENST00000381603O00241
ENSG00000101307ENST00000381605O00241
ENSG00000101307ENST00000562014H3BQ21
ENSG00000101307ENST00000563840H3BRP9
ENSG00000101307ENST00000565076H3BUW0
ENSG00000101307ENST00000565087H3BU43
ENSG00000101307ENST00000565230H3BSK5
ENSG00000101307ENST00000566055H3BU43
ENSG00000101307ENST00000568365Q5TFQ8
ENSG00000101307ENST00000569387H3BU43
ENSG00000101307ENST00000569629H3BTT9

Expression (GTEx)

0
10
20
30
40
50
60
70
80

Pathways

PathwaySourceExternal ID
Osteoclast differentiationKEGGko04380
Osteoclast differentiationKEGGhsa04380
Immune SystemREACTOMER-HSA-168256
Innate Immune SystemREACTOMER-HSA-168249
DAP12 interactionsREACTOMER-HSA-2172127
Cell-Cell communicationREACTOMER-HSA-1500931
Signal regulatory protein (SIRP) family interactionsREACTOMER-HSA-391160
Neutrophil degranulationREACTOMER-HSA-6798695

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
191655272009Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia.56
190343802009Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis.36
198930262009Signal regulatory protein-beta1: a microglial modulator of phagocytosis in Alzheimer's disease.24
223604202012Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.18
160814152011Expression of angiopoietin-like 4 (ANGPTL4) in human colorectal cancer: ANGPTL4 promotes venous invasion and distant metastasis.16
250399692014SIRPB1 copy-number polymorphism as candidate quantitative trait locus for impulsive-disinhibited personality.2

Citation

Dessen P

SIRPB1 (signal regulatory protein beta 1)

Atlas Genet Cytogenet Oncol Haematol. 2003-05-01

Online version: http://atlasgeneticsoncology.org/gene/42300/sirpb1