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SIRPB1 (signal regulatory protein beta 1)

Identity

Alias_namessignal-regulatory protein beta 1
Alias_symbol (synonym)SIRP-BETA-1
CD172b
Other alias
HGNC (Hugo) SIRPB1
LocusID (NCBI) 10326
Atlas_Id 42300
Location 20p13  [Link to chromosome band 20p13]
Location_base_pair Starts at 1564383 and ends at 1620094 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SIRPB1   15928
Cards
Entrez_Gene (NCBI)SIRPB1  10326  signal regulatory protein beta 1
AliasesCD172b; SIRP-BETA-1
GeneCards (Weizmann)SIRPB1
Ensembl hg19 (Hinxton)ENSG00000101307 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000101307 [Gene_View]  chr20:1564383-1620094 [Contig_View]  SIRPB1 [Vega]
ICGC DataPortalENSG00000101307
TCGA cBioPortalSIRPB1
AceView (NCBI)SIRPB1
Genatlas (Paris)SIRPB1
WikiGenes10326
SOURCE (Princeton)SIRPB1
Genetics Home Reference (NIH)SIRPB1
Genomic and cartography
GoldenPath hg38 (UCSC)SIRPB1  -     chr20:1564383-1620094 -  20p13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SIRPB1  -     20p13   [Description]    (hg19-Feb_2009)
EnsemblSIRPB1 - 20p13 [CytoView hg19]  SIRPB1 - 20p13 [CytoView hg38]
Mapping of homologs : NCBISIRPB1 [Mapview hg19]  SIRPB1 [Mapview hg38]
OMIM603889   
Gene and transcription
Genbank (Entrez)AK130124 AK289866 AK313517 BC025286 BC075835
RefSeq transcript (Entrez)NM_001083910 NM_001135844 NM_001329157 NM_001330639 NM_006065
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SIRPB1
Cluster EST : UnigeneHs.664861 [ NCBI ]
CGAP (NCI)Hs.664861
Alternative Splicing GalleryENSG00000101307
Gene ExpressionSIRPB1 [ NCBI-GEO ]   SIRPB1 [ EBI - ARRAY_EXPRESS ]   SIRPB1 [ SEEK ]   SIRPB1 [ MEM ]
Gene Expression Viewer (FireBrowse)SIRPB1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10326
GTEX Portal (Tissue expression)SIRPB1
Human Protein AtlasENSG00000101307-SIRPB1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5TFQ8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5TFQ8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5TFQ8
Splice isoforms : SwissVarQ5TFQ8
PhosPhoSitePlusQ5TFQ8
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_C1-set    Ig_sub    Ig_V-set   
Domain families : Pfam (Sanger)C1-set (PF07654)    V-set (PF07686)   
Domain families : Pfam (NCBI)pfam07654    pfam07686   
Domain families : Smart (EMBL)IG (SM00409)  IGc1 (SM00407)  IGv (SM00406)  
Conserved Domain (NCBI)SIRPB1
DMDM Disease mutations10326
Blocks (Seattle)SIRPB1
PDB (SRS)2JJV   
PDB (PDBSum)2JJV   
PDB (IMB)2JJV   
PDB (RSDB)2JJV   
Structural Biology KnowledgeBase2JJV   
SCOP (Structural Classification of Proteins)2JJV   
CATH (Classification of proteins structures)2JJV   
SuperfamilyQ5TFQ8
Human Protein Atlas [tissue]ENSG00000101307-SIRPB1 [tissue]
Peptide AtlasQ5TFQ8
HPRD04866
IPIIPI00299724   IPI00515053   IPI00375705   IPI00844132   IPI00514322   
Protein Interaction databases
DIP (DOE-UCLA)Q5TFQ8
IntAct (EBI)Q5TFQ8
FunCoupENSG00000101307
BioGRIDSIRPB1
STRING (EMBL)SIRPB1
ZODIACSIRPB1
Ontologies - Pathways
QuickGOQ5TFQ8
Ontology : AmiGOprotein binding  plasma membrane  integral component of plasma membrane  signal transduction  cell surface receptor signaling pathway  secretory granule membrane  neutrophil degranulation  innate immune response  extracellular exosome  
Ontology : EGO-EBIprotein binding  plasma membrane  integral component of plasma membrane  signal transduction  cell surface receptor signaling pathway  secretory granule membrane  neutrophil degranulation  innate immune response  extracellular exosome  
Pathways : KEGGOsteoclast differentiation   
NDEx NetworkSIRPB1
Atlas of Cancer Signalling NetworkSIRPB1
Wikipedia pathwaysSIRPB1
Orthology - Evolution
OrthoDB10326
GeneTree (enSembl)ENSG00000101307
Phylogenetic Trees/Animal Genes : TreeFamSIRPB1
HOVERGENQ5TFQ8
HOGENOMQ5TFQ8
Homologs : HomoloGeneSIRPB1
Homology/Alignments : Family Browser (UCSC)SIRPB1
Gene fusions - Rearrangements
Tumor Fusion PortalSIRPB1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSIRPB1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SIRPB1
dbVarSIRPB1
ClinVarSIRPB1
1000_GenomesSIRPB1 
Exome Variant ServerSIRPB1
ExAC (Exome Aggregation Consortium)ENSG00000101307
GNOMAD BrowserENSG00000101307
Genetic variants : HAPMAP10326
Genomic Variants (DGV)SIRPB1 [DGVbeta]
DECIPHERSIRPB1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSIRPB1 
Mutations
ICGC Data PortalSIRPB1 
TCGA Data PortalSIRPB1 
Broad Tumor PortalSIRPB1
OASIS PortalSIRPB1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSIRPB1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSIRPB1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SIRPB1
DgiDB (Drug Gene Interaction Database)SIRPB1
DoCM (Curated mutations)SIRPB1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SIRPB1 (select a term)
intoGenSIRPB1
Cancer3DSIRPB1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603889   
Orphanet
DisGeNETSIRPB1
MedgenSIRPB1
Genetic Testing Registry SIRPB1
NextProtQ5TFQ8 [Medical]
TSGene10326
GENETestsSIRPB1
Target ValidationSIRPB1
Huge Navigator SIRPB1 [HugePedia]
snp3D : Map Gene to Disease10326
BioCentury BCIQSIRPB1
ClinGenSIRPB1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10326
Chemical/Pharm GKB GenePA38051
Clinical trialSIRPB1
Miscellaneous
canSAR (ICR)SIRPB1 (select the gene name)
Probes
Litterature
PubMed22 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSIRPB1
EVEXSIRPB1
GoPubMedSIRPB1
iHOPSIRPB1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 14:34:40 CET 2017

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