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SIRPB2 (signal regulatory protein beta 2)

Identity

Alias_namesPTPN1L
PTPNS1L3
protein tyrosine phosphatase, non-receptor type 1-like
protein tyrosine phosphatase, non-receptor type substrate 1-like 3
signal-regulatory protein beta 2
Alias_symbol (synonym)dJ776F14.2
Other alias
HGNC (Hugo) SIRPB2
LocusID (NCBI) 284759
Atlas_Id 49900
Location 20p13  [Link to chromosome band 20p13]
Location_base_pair Starts at 1474591 and ends at 1491587 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SIRPB2 (20p13) / HSPA1A (6p21.33)SIRPB2 (20p13) / NSFL1C (20p13)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SIRPB2   16247
Cards
Entrez_Gene (NCBI)SIRPB2  284759  signal regulatory protein beta 2
AliasesPTPN1L; PTPNS1L3; dJ776F14.2
GeneCards (Weizmann)SIRPB2
Ensembl hg19 (Hinxton)ENSG00000196209 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000196209 [Gene_View]  chr20:1474591-1491587 [Contig_View]  SIRPB2 [Vega]
ICGC DataPortalENSG00000196209
TCGA cBioPortalSIRPB2
AceView (NCBI)SIRPB2
Genatlas (Paris)SIRPB2
WikiGenes284759
SOURCE (Princeton)SIRPB2
Genetics Home Reference (NIH)SIRPB2
Genomic and cartography
GoldenPath hg38 (UCSC)SIRPB2  -     chr20:1474591-1491587 -  20p13   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SIRPB2  -     20p13   [Description]    (hg19-Feb_2009)
EnsemblSIRPB2 - 20p13 [CytoView hg19]  SIRPB2 - 20p13 [CytoView hg38]
Mapping of homologs : NCBISIRPB2 [Mapview hg19]  SIRPB2 [Mapview hg38]
Gene and transcription
Genbank (Entrez)AK095499 AK294440 AK297072 AY424277 BG539998
RefSeq transcript (Entrez)NM_001122962 NM_001134836
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SIRPB2
Cluster EST : UnigeneHs.721685 [ NCBI ]
CGAP (NCI)Hs.721685
Alternative Splicing GalleryENSG00000196209
Gene ExpressionSIRPB2 [ NCBI-GEO ]   SIRPB2 [ EBI - ARRAY_EXPRESS ]   SIRPB2 [ SEEK ]   SIRPB2 [ MEM ]
Gene Expression Viewer (FireBrowse)SIRPB2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)284759
GTEX Portal (Tissue expression)SIRPB2
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ5JXA9   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ5JXA9  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ5JXA9
Splice isoforms : SwissVarQ5JXA9
PhosPhoSitePlusQ5JXA9
Domaine pattern : Prosite (Expaxy)IG_LIKE (PS50835)   
Domains : Interpro (EBI)Ig-like_dom    Ig-like_fold    Ig_sub    Ig_sub2    Ig_V-set   
Domain families : Pfam (Sanger)V-set (PF07686)   
Domain families : Pfam (NCBI)pfam07686   
Domain families : Smart (EMBL)IG (SM00409)  IGc2 (SM00408)  
Conserved Domain (NCBI)SIRPB2
DMDM Disease mutations284759
Blocks (Seattle)SIRPB2
SuperfamilyQ5JXA9
Human Protein AtlasENSG00000196209
Peptide AtlasQ5JXA9
IPIIPI00552528   IPI00922106   IPI00895919   IPI00552742   IPI00983836   
Protein Interaction databases
DIP (DOE-UCLA)Q5JXA9
IntAct (EBI)Q5JXA9
FunCoupENSG00000196209
BioGRIDSIRPB2
STRING (EMBL)SIRPB2
ZODIACSIRPB2
Ontologies - Pathways
QuickGOQ5JXA9
Ontology : AmiGOintegral component of membrane  
Ontology : EGO-EBIintegral component of membrane  
NDEx NetworkSIRPB2
Atlas of Cancer Signalling NetworkSIRPB2
Wikipedia pathwaysSIRPB2
Orthology - Evolution
OrthoDB284759
GeneTree (enSembl)ENSG00000196209
Phylogenetic Trees/Animal Genes : TreeFamSIRPB2
HOVERGENQ5JXA9
HOGENOMQ5JXA9
Homologs : HomoloGeneSIRPB2
Homology/Alignments : Family Browser (UCSC)SIRPB2
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSIRPB2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SIRPB2
dbVarSIRPB2
ClinVarSIRPB2
1000_GenomesSIRPB2 
Exome Variant ServerSIRPB2
ExAC (Exome Aggregation Consortium)SIRPB2 (select the gene name)
Genetic variants : HAPMAP284759
Genomic Variants (DGV)SIRPB2 [DGVbeta]
DECIPHERSIRPB2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSIRPB2 
Mutations
ICGC Data PortalSIRPB2 
TCGA Data PortalSIRPB2 
Broad Tumor PortalSIRPB2
OASIS PortalSIRPB2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSIRPB2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSIRPB2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SIRPB2
DgiDB (Drug Gene Interaction Database)SIRPB2
DoCM (Curated mutations)SIRPB2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SIRPB2 (select a term)
intoGenSIRPB2
Cancer3DSIRPB2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM
Orphanet
MedgenSIRPB2
Genetic Testing Registry SIRPB2
NextProtQ5JXA9 [Medical]
TSGene284759
GENETestsSIRPB2
Target ValidationSIRPB2
Huge Navigator SIRPB2 [HugePedia]
snp3D : Map Gene to Disease284759
BioCentury BCIQSIRPB2
ClinGenSIRPB2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD284759
Chemical/Pharm GKB GenePA164742382
Clinical trialSIRPB2
Miscellaneous
canSAR (ICR)SIRPB2 (select the gene name)
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSIRPB2
EVEXSIRPB2
GoPubMedSIRPB2
iHOPSIRPB2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 17:14:32 CEST 2017

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