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SIRT7 (sirtuin 7)

Identity

Other namesSIR2L7
HGNC (Hugo) SIRT7
LocusID (NCBI) 51547
Location 17q25.3
Location_base_pair Starts at 79869815 and ends at 79876058 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SIRT7   14935
Entrez_Gene (NCBI)SIRT7  51547  sirtuin 7
Cards
GeneCards (Weizmann)SIRT7
Ensembl (Hinxton)ENSG00000187531 [Gene_View]  chr17:79869815-79876058 [Contig_View]  SIRT7 [Vega]
AceView (NCBI)SIRT7
Genatlas (Paris)SIRT7
SOURCE (Stanford)NM_016538
Genomic and cartography
GoldenPath (UCSC)SIRT7  -  17q25.3   chr17:79869815-79876058 -  17q25.3   [Description]    (hg19-Feb_2009)
EnsemblSIRT7 - 17q25.3 [CytoView]
Mapping of homologs : NCBISIRT7 [Mapview]
OMIM606212   
Gene and transcription
Genbank (Entrez)AF233395 AK002027 AK094326 AK131437 AK131484
RefSeq transcript (SRS)NM_016538
RefSeq transcript (Entrez)NM_016538
RefSeq genomic (SRS)AC_000149 NC_000017 NC_018928 NT_010663 NW_001838459 NW_004078093
RefSeq genomic (Entrez)AC_000149 NC_000017 NC_018928 NT_010663 NW_001838459 NW_004078093
Consensus coding sequences : CCDS (NCBI)SIRT7
Cluster EST : UnigeneHs.514636 [ SRS ] Hs.514636 [ NCBI ]
CGAP (NCI)Hs.514636
Alternative Splicing : Fast-db (Paris)GSHG0013831
Alternative Splicing GalleryENSG00000187531
Gene ExpressionSIRT7 [ NCBI-GEO ]   SIRT7 [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9NRC8 (SRS) Q9NRC8 (Uniprot)
NextProtQ9NRC8
With graphics : InterProQ9NRC8
Splice isoforms : SwissVarQ9NRC8(Swissvar)
Domaine pattern : Prosite (SRS)SIRTUIN (PS50305)   
Domaine pattern : Prosite (Expaxy)SIRTUIN (PS50305)   
Domains : Interpro (SRS)Sirtuin    Ssirtuin_cat_dom   
Domains : Interpro (EBI)Sirtuin    Ssirtuin_cat_dom   
Related proteins : CluSTrQ9NRC8
Domain families : Pfam (SRS)SIR2 (PF02146)   
Domain families : Pfam (Sanger)SIR2 (PF02146)   
Domain families : Pfam (NCBI)pfam02146   
DMDM51547
Blocks (Seattle)Q9NRC8
Human Protein AtlasENSG00000187531
HPRD12094
IPIIPI00334648   IPI00383601   IPI01015878   
Protein Interaction databases
DIP (DOE-UCLA)Q9NRC8
IntAct (EBI)Q9NRC8
FunCoupENSG00000187531
REACTOMESIRT7
Protein Interaction Database51547
BioGRIDSIRT7
InParanoidQ9NRC8
Interologous Interaction database Q9NRC8
IntegromeDBSIRT7
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)SIRT7
SNP (GeneSNP Utah)SIRT7
SNP : HGBaseSIRT7
Genetic variants : HAPMAPSIRT7
Somatic Mutations in Cancer : COSMICSIRT7 
CONAN: Copy Number AnalysisSIRT7 
Mutations and Diseases : HGMDSIRT7
OMIM606212   
GENETests606212   
Disease Genetic AssociationSIRT7
Huge Navigator SIRT7 [HugePedia]  SIRT7 [HugeCancerGEM]
Genomic VariantsSIRT7  SIRT7 [DGVbeta]
snp3D : Map Gene to Disease51547
General knowledge
Homologs : HomoloGeneSIRT7
Homology/Alignments : Family Browser (UCSC)SIRT7
Phylogenetic Trees/Animal Genes : TreeFamSIRT7
Catalytic activity : Enzyme3.5.1.- [ Enzyme-Expasy ]   3.5.1.- [ Enzyme-SRS ]   3.5.1.- [ IntEnz-EBI ]   3.5.1.- [ BRENDA ]   3.5.1.- [ KEGG ]   
Chemical/Protein Interactions : CTD51547
Chemical/Pharm GKB GenePA37940
Clinical trialSIRT7
Cancer Resource (Charite)ENSG00000187531
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  chromatin binding  protein binding  nucleolus  nucleolus organizer region  cytoplasm  positive regulation of transcription on exit from mitosis  rRNA transcription  metal ion binding  NAD+ binding  histone H3 deacetylation  NAD-dependent histone deacetylase activity (H3-K18 specific)  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  chromatin binding  protein binding  nucleolus  nucleolus organizer region  cytoplasm  positive regulation of transcription on exit from mitosis  rRNA transcription  metal ion binding  NAD+ binding  histone H3 deacetylation  NAD-dependent histone deacetylase activity (H3-K18 specific)  
Pathways : KEGGPantothenate and CoA biosynthesisNicotinate and nicotinamide metabolismCaprolactam degradation
Other databases
Probes
Litterature
PubMed18 Pubmed reference(s) in Entrez
PubGeneSIRT7
iHOPSIRT7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:35:13 CEST 2013
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