Slc12a2 is a direct target of two closely related homeobox proteins, Six1 and Six4. |
Ando Z, Sato S, Ikeda K, Kawakami K |
The FEBS journal. 2005 ; 272 (12) : 3026-3041. |
PMID 15955062 |
|
Expression of zebrafish six1 during sensory organ development and myogenesis. |
Bessarab DA, Chong SW, Korzh V |
Developmental dynamics : an official publication of the American Association of Anatomists. 2004 ; 230 (4) : 781-786. |
PMID 15254912 |
|
Six1 is not involved in limb tendon development, but is expressed in limb connective tissue under Shh regulation. |
Bonnin MA, Laclef C, Blaise R, Eloy-Trinquet S, Relaix F, Maire P, Duprez D |
Mechanisms of development. 2005 ; 122 (4) : 573-585. |
PMID 15804569 |
|
Cloning of the human SIX1 gene and its assignment to chromosome 14. |
Boucher CA, Carey N, Edwards YH, Siciliano MJ, Johnson KJ |
Genomics. 1996 ; 33 (1) : 140-142. |
PMID 8617500 |
|
Genetic determination of nephrogenesis: the Pax/Eya/Six gene network. |
Brodbeck S, Englert C |
Pediatric nephrology (Berlin, Germany). 2004 ; 19 (3) : 249-255. |
PMID 14673635 |
|
Six1 promotes a placodal fate within the lateral neurogenic ectoderm by functioning as both a transcriptional activator and repressor. |
Brugmann SA, Pandur PD, Kenyon KL, Pignoni F, Moody SA |
Development (Cambridge, England). 2004 ; 131 (23) : 5871-5881. |
PMID 15525662 |
|
The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1. |
Coletta RD, Christensen K, Reichenberger KJ, Lamb J, Micomonaco D, Huang L, Wolf DM, Müller-Tidow C, Golub TR, Kawakami K, Ford HL |
Proceedings of the National Academy of Sciences of the United States of America. 2004 ; 101 (17) : 6478-6483. |
PMID 15123840 |
|
Signal transduction: an eye on organ development. |
Epstein JA, Neel BG |
Nature. 2003 ; 426 (6964) : 238-239. |
PMID 14628032 |
|
Abrogation of the G2 cell cycle checkpoint associated with overexpression of HSIX1: a possible mechanism of breast carcinogenesis. |
Ford HL, Kabingu EN, Bump EA, Mutter GL, Pardee AB |
Proceedings of the National Academy of Sciences of the United States of America. 1998 ; 95 (21) : 12608-12613. |
PMID 9770533 |
|
Cell cycle-regulated phosphorylation of the human SIX1 homeodomain protein. |
Ford HL, Landesman-Bollag E, Dacwag CS, Stukenberg PT, Pardee AB, Seldin DC |
The Journal of biological chemistry. 2000 ; 275 (29) : 22245-22254. |
PMID 10801845 |
|
Six and Eya expression during human somitogenesis and MyoD gene family activation. |
Fougerousse F, Durand M, Lopez S, Suel L, Demignon J, Thornton C, Ozaki H, Kawakami K, Barbet P, Beckmann JS, Maire P |
Journal of muscle research and cell motility. 2002 ; 23 (3) : 255-264. |
PMID 12500905 |
|
Genomic cloning and characterization of the human homeobox gene SIX6 reveals a cluster of SIX genes in chromosome 14 and associates SIX6 hemizygosity with bilateral anophthalmia and pituitary anomalies. |
Gallardo ME, Lopez-Rios J, Fernaud-Espinosa I, Granadino B, Sanz R, Ramos C, Ayuso C, Seller MJ, Brunner HG, Bovolenta P, Rodríguez de Córdoba S |
Genomics. 1999 ; 61 (1) : 82-91. |
PMID 10512683 |
|
New perspectives on eye development and the evolution of eyes and photoreceptors. |
Gehring WJ |
The Journal of heredity. 2005 ; 96 (3) : 171-184. |
PMID 15653558 |
|
Six1 and Six4 homeoproteins are required for Pax3 and Mrf expression during myogenesis in the mouse embryo. |
Grifone R, Demignon J, Houbron C, Souil E, Niro C, Seller MJ, Hamard G, Maire P |
Development (Cambridge, England). 2005 ; 132 (9) : 2235-2249. |
PMID 15788460 |
|
Six1 and Eya1 expression can reprogram adult muscle from the slow-twitch phenotype into the fast-twitch phenotype. |
Grifone R, Laclef C, Spitz F, Lopez S, Demignon J, Guidotti JE, Kawakami K, Xu PX, Kelly R, Petrof BJ, Daegelen D, Concordet JP, Maire P |
Molecular and cellular biology. 2004 ; 24 (14) : 6253-6267. |
PMID 15226428 |
|
Synergistic regulation of vertebrate muscle development by Dach2, Eya2, and Six1, homologs of genes required for Drosophila eye formation. |
Heanue TA, Reshef R, Davis RJ, Mardon G, Oliver G, Tomarev S, Lassar AB, Tabin CJ |
Genes & development. 1999 ; 13 (24) : 3231-3243. |
PMID 10617572 |
|
Molecular interaction and synergistic activation of a promoter by Six, Eya, and Dach proteins mediated through CREB binding protein. |
Ikeda K, Watanabe Y, Ohto H, Kawakami K |
Molecular and cellular biology. 2002 ; 22 (19) : 6759-6766. |
PMID 12215533 |
|
Six family genes--structure and function as transcription factors and their roles in development. |
Kawakami K, Sato S, Ozaki H, Ikeda K |
BioEssays : news and reviews in molecular, cellular and developmental biology. 2000 ; 22 (7) : 616-626. |
PMID 10878574 |
|
cDNA microarrays detect activation of a myogenic transcription program by the PAX3-FKHR fusion oncogene. |
Khan J, Bittner ML, Saal LH, Teichmann U, Azorsa DO, Gooden GC, Pavan WJ, Trent JM, Meltzer PS |
Proceedings of the National Academy of Sciences of the United States of America. 1999 ; 96 (23) : 13264-13269. |
PMID 10557309 |
|
Altered myogenesis in Six1-deficient mice. |
Laclef C, Hamard G, Demignon J, Souil E, Houbron C, Maire P |
Development (Cambridge, England). 2003 ; 130 (10) : 2239-2252. |
PMID 12668636 |
|
Thymus, kidney and craniofacial abnormalities in Six 1 deficient mice. |
Laclef C, Souil E, Demignon J, Maire P |
Mechanisms of development. 2003 ; 120 (6) : 669-679. |
PMID 12834866 |
|
Gene expression in Wilms' tumor mimics the earliest committed stage in the metanephric mesenchymal-epithelial transition. |
Li CM, Guo M, Borczuk A, Powell CA, Wei M, Thaker HM, Friedman R, Klein U, Tycko B |
The American journal of pathology. 2002 ; 160 (6) : 2181-2190. |
PMID 12057921 |
|
Eya protein phosphatase activity regulates Six1-Dach-Eya transcriptional effects in mammalian organogenesis. |
Li X, Oghi KA, Zhang J, Krones A, Bush KT, Glass CK, Nigam SK, Aggarwal AK, Maas R, Rose DW, Rosenfeld MG |
Nature. 2003 ; 426 (6964) : 247-254. |
PMID 14628042 |
|
Homeobox genes and connective tissue patterning. |
Oliver G, Wehr R, Jenkins NA, Copeland NG, Cheyette BN, Hartenstein V, Zipursky SL, Gruss P |
Development (Cambridge, England). 1995 ; 121 (3) : 693-705. |
PMID 7720577 |
|
Six1 controls patterning of the mouse otic vesicle. |
Ozaki H, Nakamura K, Funahashi J, Ikeda K, Yamada G, Tokano H, Okamura HO, Kitamura K, Muto S, Kotaki H, Sudo K, Horai R, Iwakura Y, Kawakami K |
Development (Cambridge, England). 2004 ; 131 (3) : 551-562. |
PMID 14695375 |
|
Xenopus Six1 gene is expressed in neurogenic cranial placodes and maintained in the differentiating lateral lines. |
Pandur PD, Moody SA |
Mechanisms of development. 2000 ; 96 (2) : 253-257. |
PMID 10960794 |
|
Gene amplification is a mechanism of Six1 overexpression in breast cancer. |
Reichenberger KJ, Coletta RD, Schulte AP, Varella-Garcia M, Ford HL |
Cancer research. 2005 ; 65 (7) : 2668-2675. |
PMID 15805264 |
|
From insect eye to vertebrate muscle: redeployment of a regulatory network. |
Relaix F, Buckingham M |
Genes & development. 1999 ; 13 (24) : 3171-3178. |
PMID 10617565 |
|
The Human Six family of homeobox genes. |
Rodríguez de Córdoba S, Gallardo ME, López-R&ios J, Bovolenta P |
Current Genomics. 2001 ; 2 : 231-242. |
|
SIX1 mutations cause branchio-oto-renal syndrome by disruption of EYA1-SIX1-DNA complexes. |
Ruf RG, Xu PX, Silvius D, Otto EA, Beekmann F, Muerb UT, Kumar S, Neuhaus TJ, Kemper MJ, Raymond RM Jr, Brophy PD, Berkman J, Gattas M, Hyland V, Ruf EM, Schwartz C, Chang EH, Smith RJ, Stratakis CA, Weil D, Petit C, Hildebrandt F |
Proceedings of the National Academy of Sciences of the United States of America. 2004 ; 101 (21) : 8090-8095. |
PMID 15141091 |
|
Expression of myogenin during embryogenesis is controlled by Six/sine oculis homeoproteins through a conserved MEF3 binding site. |
Spitz F, Demignon J, Porteu A, Kahn A, Concordet JP, Daegelen D, Maire P |
Proceedings of the National Academy of Sciences of the United States of America. 1998 ; 95 (24) : 14220-14225. |
PMID 9826681 |
|
Six1 is required for the early organogenesis of mammalian kidney. |
Xu PX, Zheng W, Huang L, Maire P, Laclef C, Silvius D |
Development (Cambridge, England). 2003 ; 130 (14) : 3085-3094. |
PMID 12783782 |
|
Expression profiling identifies the cytoskeletal organizer ezrin and the developmental homeoprotein Six-1 as key metastatic regulators. |
Yu Y, Khan J, Khanna C, Helman L, Meltzer PS, Merlino G |
Nature medicine. 2004 ; 10 (2) : 175-181. |
PMID 14704789 |
|
The role of Six1 in mammalian auditory system development. |
Zheng W, Huang L, Wei ZB, Silvius D, Tang B, Xu PX |
Development (Cambridge, England). 2003 ; 130 (17) : 3989-4000. |
PMID 12874121 |
|
Eya1 and Six1 are essential for early steps of sensory neurogenesis in mammalian cranial placodes. |
Zou D, Silvius D, Fritzsch B, Xu PX |
Development (Cambridge, England). 2004 ; 131 (22) : 5561-5572. |
PMID 15496442 |
|