Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SKIL (SKI-like oncogene)

Identity

Other namesSNO
SnoA
SnoI
SnoN
HGNC (Hugo) SKIL
LocusID (NCBI) 6498
Location 3q26.2
Location_base_pair Starts at 170077411 and ends at 170114637 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SKIL   10897
Cards
Entrez_Gene (NCBI)SKIL  6498  SKI-like oncogene
GeneCards (Weizmann)SKIL
Ensembl (Hinxton)ENSG00000136603 [Gene_View]  chr3:170077411-170114637 [Contig_View]  SKIL [Vega]
ICGC DataPortalENSG00000136603
cBioPortalSKIL
AceView (NCBI)SKIL
Genatlas (Paris)SKIL
WikiGenes6498
SOURCE (Princeton)NM_001145097 NM_001145098 NM_001248008 NM_005414
Genomic and cartography
GoldenPath (UCSC)SKIL  -  3q26.2   chr3:170077411-170114637 +  3q26.2   [Description]    (hg19-Feb_2009)
EnsemblSKIL - 3q26.2 [CytoView]
Mapping of homologs : NCBISKIL [Mapview]
OMIM165340   
Gene and transcription
Genbank (Entrez)AA827643 AA827646 AI245308 AK300053 BC041913
RefSeq transcript (Entrez)NM_001145097 NM_001145098 NM_001248008 NM_005414
RefSeq genomic (Entrez)AC_000135 NC_000003 NC_018914 NG_030357 NT_005612 NW_001838884 NW_004929311
Consensus coding sequences : CCDS (NCBI)SKIL
Cluster EST : UnigeneHs.581632 [ NCBI ]
CGAP (NCI)Hs.581632
Alternative Splicing : Fast-db (Paris)GSHG0021313
Alternative Splicing GalleryENSG00000136603
Gene ExpressionSKIL [ NCBI-GEO ]     SKIL [ SEEK ]   SKIL [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP12757 (Uniprot)
NextProtP12757  [Medical]
With graphics : InterProP12757
Splice isoforms : SwissVarP12757 (Swissvar)
Domains : Interpro (EBI)c-SKI_SMAD4-bd_dom [organisation]   DNA-bd_dom_put [organisation]   SAND_dom-like [organisation]   Transform_Ski [organisation]   Tscrpt_reg_SKI_SnoN [organisation]  
Related proteins : CluSTrP12757
Domain families : Pfam (Sanger)c-SKI_SMAD_bind (PF08782)    Ski_Sno (PF02437)   
Domain families : Pfam (NCBI)pfam08782    pfam02437   
Domain families : Smart (EMBL)c-SKI_SMAD_bind (SM01046)  
DMDM Disease mutations6498
Blocks (Seattle)P12757
PDB (SRS)3EQ5   
PDB (PDBSum)3EQ5   
PDB (IMB)3EQ5   
PDB (RSDB)3EQ5   
Human Protein AtlasENSG00000136603 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasP12757
HPRD01319
IPIIPI00025468   IPI00216658   IPI00216661   IPI00867624   IPI00953209   IPI00945104   IPI00944941   
Protein Interaction databases
DIP (DOE-UCLA)P12757
IntAct (EBI)P12757
FunCoupENSG00000136603
BioGRIDSKIL
InParanoidP12757
Interologous Interaction database P12757
IntegromeDBSKIL
STRING (EMBL)SKIL
Ontologies - Pathways
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  negative regulation of transcription from RNA polymerase II promoter  nucleotide binding  blastocyst formation  lymphocyte homeostasis  DNA binding  chromatin binding  chromatin binding  transcription corepressor activity  protein binding  nucleus  nucleoplasm  cytoplasm  transcription, DNA-templated  transcription initiation from RNA polymerase II promoter  cell cycle arrest  cell cycle arrest  transforming growth factor beta receptor signaling pathway  skeletal muscle tissue development  gene expression  PML body  protein domain specific binding  negative regulation of transforming growth factor beta receptor signaling pathway  negative regulation of transforming growth factor beta receptor signaling pathway  protein complex binding  regulation of apoptotic process  regulation of apoptotic process  negative regulation of cell differentiation  negative regulation of cell differentiation  SMAD binding  SMAD binding  response to antibiotic  positive regulation of axonogenesis  protein homotrimerization  protein heterotrimerization  lens fiber cell differentiation  response to growth factor  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  negative regulation of transcription from RNA polymerase II promoter  nucleotide binding  blastocyst formation  lymphocyte homeostasis  DNA binding  chromatin binding  chromatin binding  transcription corepressor activity  protein binding  nucleus  nucleoplasm  cytoplasm  transcription, DNA-templated  transcription initiation from RNA polymerase II promoter  cell cycle arrest  cell cycle arrest  transforming growth factor beta receptor signaling pathway  skeletal muscle tissue development  gene expression  PML body  protein domain specific binding  negative regulation of transforming growth factor beta receptor signaling pathway  negative regulation of transforming growth factor beta receptor signaling pathway  protein complex binding  regulation of apoptotic process  regulation of apoptotic process  negative regulation of cell differentiation  negative regulation of cell differentiation  SMAD binding  SMAD binding  response to antibiotic  positive regulation of axonogenesis  protein homotrimerization  protein heterotrimerization  lens fiber cell differentiation  response to growth factor  
Pathways : BIOCARTATGF beta signaling pathway [Genes]   
Protein Interaction DatabaseSKIL
Wikipedia pathwaysSKIL
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)SKIL
snp3D : Map Gene to Disease6498
SNP (GeneSNP Utah)SKIL
SNP : HGBaseSKIL
Genetic variants : HAPMAPSKIL
Exome VariantSKIL
1000_GenomesSKIL 
ICGC programENSG00000136603 
Somatic Mutations in Cancer : COSMICSKIL 
CONAN: Copy Number AnalysisSKIL 
Mutations and Diseases : HGMDSKIL
Genomic VariantsSKIL  SKIL [DGVbeta]
dbVarSKIL
ClinVarSKIL
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM165340   
MedgenSKIL
GENETestsSKIL
Disease Genetic AssociationSKIL
Huge Navigator SKIL [HugePedia]  SKIL [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneSKIL
Homology/Alignments : Family Browser (UCSC)SKIL
Phylogenetic Trees/Animal Genes : TreeFamSKIL
Chemical/Protein Interactions : CTD6498
Chemical/Pharm GKB GenePA35797
Clinical trialSKIL
Cancer Resource (Charite)ENSG00000136603
Other databases
Probes
Litterature
PubMed74 Pubmed reference(s) in Entrez
CoreMineSKIL
iHOPSKIL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jul 11 17:19:06 CEST 2014

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.