Atlas of Genetics and Cytogenetics in Oncology and Haematology

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SKIL (SKI-like oncogene)

Identity

Other namesSNO
SnoA
SnoI
SnoN
HGNC (Hugo) SKIL
LocusID (NCBI) 6498
Location 3q26.2
Location_base_pair Starts at 170077411 and ends at 170114637 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

External links

Nomenclature
HGNC (Hugo)SKIL   10897
Entrez_Gene (NCBI)SKIL  6498  SKI-like oncogene
Cards
GeneCards (Weizmann)SKIL
Ensembl (Hinxton)ENSG00000136603 [Gene_View]  chr3:170077411-170114637 [Contig_View]  SKIL [Vega]
AceView (NCBI)SKIL
Genatlas (Paris)SKIL
SOURCE (Stanford)NM_001145097 NM_001145098 NM_001248008 NM_005414
Genomic and cartography
GoldenPath (UCSC)SKIL  -  3q26.2   chr3:170077411-170114637 +  3q26.2   [Description]    (hg19-Feb_2009)
EnsemblSKIL - 3q26.2 [CytoView]
Mapping of homologs : NCBISKIL [Mapview]
OMIM165340   
Gene and transcription
Genbank (Entrez)AA827643 AA827646 AI245308 AK300053 BC041913
RefSeq transcript (SRS)NM_001145097 NM_001145098 NM_001248008 NM_005414
RefSeq transcript (Entrez)NM_001145097 NM_001145098 NM_001248008 NM_005414
RefSeq genomic (SRS)AC_000135 NC_000003 NC_018914 NG_030357 NT_005612 NW_001838884 NW_004078013
RefSeq genomic (Entrez)AC_000135 NC_000003 NC_018914 NG_030357 NT_005612 NW_001838884 NW_004078013
Consensus coding sequences : CCDS (NCBI)SKIL
Cluster EST : UnigeneHs.581632 [ SRS ] Hs.581632 [ NCBI ]
CGAP (NCI)Hs.581632
Alternative Splicing : Fast-db (Paris)GSHG0021313
Alternative Splicing GalleryENSG00000136603
Gene ExpressionSKIL [ NCBI-GEO ]   SKIL [ EBI - ARRAY_EXPRESS ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtP12757 (SRS) P12757 (Uniprot)
NextProtP12757
With graphics : InterProP12757
Splice isoforms : SwissVarP12757(Swissvar)
Domains : Interpro (SRS)c-SKI_SMAD4-bd_dom    DNA-bd_dom_put    SAND_dom-like    Transform_Ski    Tscrpt_reg_SKI_SnoN   
Domains : Interpro (EBI)c-SKI_SMAD4-bd_dom    DNA-bd_dom_put    SAND_dom-like    Transform_Ski    Tscrpt_reg_SKI_SnoN   
Related proteins : CluSTrP12757
Domain families : Pfam (SRS)c-SKI_SMAD_bind (PF08782)    Ski_Sno (PF02437)   
Domain families : Pfam (Sanger)c-SKI_SMAD_bind (PF08782)    Ski_Sno (PF02437)   
Domain families : Pfam (NCBI)pfam08782    pfam02437   
Domain families : Smart (EMBL)c-SKI_SMAD_bind (SM01046)  
DMDM6498
Blocks (Seattle)P12757
PDB (SRS)3EQ5   
PDB (PDBSum)3EQ5   
PDB (IMB)3EQ5   
PDB (RSDB)3EQ5   
Human Protein AtlasENSG00000136603
HPRD01319
IPIIPI00025468   IPI00216658   IPI00216661   IPI00867624   IPI00953209   IPI00945104   IPI00944941   
Protein Interaction databases
DIP (DOE-UCLA)P12757
IntAct (EBI)P12757
FunCoupENSG00000136603
REACTOMESKIL
Protein Interaction Database6498
BioGRIDSKIL
InParanoidP12757
Interologous Interaction database P12757
IntegromeDBSKIL
Polymorphism : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)SKIL
SNP (GeneSNP Utah)SKIL
SNP : HGBaseSKIL
Genetic variants : HAPMAPSKIL
Somatic Mutations in Cancer : COSMICSKIL 
CONAN: Copy Number AnalysisSKIL 
Mutations and Diseases : HGMDSKIL
OMIM165340   
GENETests165340   
Disease Genetic AssociationSKIL
Huge Navigator SKIL [HugePedia]  SKIL [HugeCancerGEM]
Genomic VariantsSKIL  SKIL [DGVbeta]
snp3D : Map Gene to Disease6498
General knowledge
Homologs : HomoloGeneSKIL
Homology/Alignments : Family Browser (UCSC)SKIL
Phylogenetic Trees/Animal Genes : TreeFamSKIL
Chemical/Protein Interactions : CTD6498
Chemical/Pharm GKB GenePA35797
Clinical trialSKIL
Cancer Resource (Charite)ENSG00000136603
Ontology : AmiGOnegative regulation of transcription from RNA polymerase II promoter  negative regulation of transcription from RNA polymerase II promoter  nucleotide binding  blastocyst formation  lymphocyte homeostasis  DNA binding  chromatin binding  chromatin binding  transcription corepressor activity  protein binding  nucleus  nucleoplasm  cytoplasm  transcription, DNA-dependent  transcription initiation from RNA polymerase II promoter  cell cycle arrest  cell cycle arrest  transforming growth factor beta receptor signaling pathway  skeletal muscle tissue development  gene expression  PML body  protein domain specific binding  negative regulation of transforming growth factor beta receptor signaling pathway  negative regulation of transforming growth factor beta receptor signaling pathway  protein complex binding  regulation of apoptotic process  regulation of apoptotic process  negative regulation of cell differentiation  negative regulation of cell differentiation  SMAD binding  SMAD binding  response to antibiotic  positive regulation of axonogenesis  protein homotrimerization  protein heterotrimerization  lens fiber cell differentiation  response to growth factor stimulus  
Ontology : EGO-EBInegative regulation of transcription from RNA polymerase II promoter  negative regulation of transcription from RNA polymerase II promoter  nucleotide binding  blastocyst formation  lymphocyte homeostasis  DNA binding  chromatin binding  chromatin binding  transcription corepressor activity  protein binding  nucleus  nucleoplasm  cytoplasm  transcription, DNA-dependent  transcription initiation from RNA polymerase II promoter  cell cycle arrest  cell cycle arrest  transforming growth factor beta receptor signaling pathway  skeletal muscle tissue development  gene expression  PML body  protein domain specific binding  negative regulation of transforming growth factor beta receptor signaling pathway  negative regulation of transforming growth factor beta receptor signaling pathway  protein complex binding  regulation of apoptotic process  regulation of apoptotic process  negative regulation of cell differentiation  negative regulation of cell differentiation  SMAD binding  SMAD binding  response to antibiotic  positive regulation of axonogenesis  protein homotrimerization  protein heterotrimerization  lens fiber cell differentiation  response to growth factor stimulus  
Pathways : BIOCARTATGF beta signaling pathway [Genes]   
Other databases
Probes
Litterature
PubMed66 Pubmed reference(s) in Entrez
PubGeneSKIL
iHOPSKIL
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated01-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 1 12:28:23 CEST 2013
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