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SKOR2 (SKI family transcriptional corepressor 2)

Identity

Alias_symbol (synonym)CORL2
FUSSEL18
Fussel-18
Other aliasCH18515
HGNC (Hugo) SKOR2
LocusID (NCBI) 652991
Atlas_Id 51550
Location 18q21.1  [Link to chromosome band 18q21]
Location_base_pair Starts at 47231123 and ends at 47249183 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SKOR2   32695
Cards
Entrez_Gene (NCBI)SKOR2  652991  SKI family transcriptional corepressor 2
AliasesCH18515; CORL2; FUSSEL18
GeneCards (Weizmann)SKOR2
Ensembl hg19 (Hinxton)ENSG00000215474 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000215474 [Gene_View]  chr18:47231123-47249183 [Contig_View]  SKOR2 [Vega]
ICGC DataPortalENSG00000215474
TCGA cBioPortalSKOR2
AceView (NCBI)SKOR2
Genatlas (Paris)SKOR2
WikiGenes652991
SOURCE (Princeton)SKOR2
Genetics Home Reference (NIH)SKOR2
Genomic and cartography
GoldenPath hg38 (UCSC)SKOR2  -     chr18:47231123-47249183 -  18q21.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SKOR2  -     18q21.1   [Description]    (hg19-Feb_2009)
EnsemblSKOR2 - 18q21.1 [CytoView hg19]  SKOR2 - 18q21.1 [CytoView hg38]
Mapping of homologs : NCBISKOR2 [Mapview hg19]  SKOR2 [Mapview hg38]
OMIM617138   
Gene and transcription
Genbank (Entrez)AY669508 AY947523 DW009659
RefSeq transcript (Entrez)NM_001037802 NM_001278063
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SKOR2
Cluster EST : UnigeneHs.585834 [ NCBI ]
CGAP (NCI)Hs.585834
Alternative Splicing GalleryENSG00000215474
Gene ExpressionSKOR2 [ NCBI-GEO ]   SKOR2 [ EBI - ARRAY_EXPRESS ]   SKOR2 [ SEEK ]   SKOR2 [ MEM ]
Gene Expression Viewer (FireBrowse)SKOR2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)652991
GTEX Portal (Tissue expression)SKOR2
Human Protein AtlasENSG00000215474-SKOR2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ2VWA4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ2VWA4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ2VWA4
Splice isoforms : SwissVarQ2VWA4
PhosPhoSitePlusQ2VWA4
Domains : Interpro (EBI)c-SKI_SMAD4-bd_dom    DNA-bd_dom_put    SAND_dom-like    SKI_corepress_2    Transform_Ski    Tscrpt_reg_SKI_SnoN   
Domain families : Pfam (Sanger)c-SKI_SMAD_bind (PF08782)    Ski_Sno (PF02437)   
Domain families : Pfam (NCBI)pfam08782    pfam02437   
Domain families : Smart (EMBL)c-SKI_SMAD_bind (SM01046)  
Conserved Domain (NCBI)SKOR2
DMDM Disease mutations652991
Blocks (Seattle)SKOR2
SuperfamilyQ2VWA4
Human Protein Atlas [tissue]ENSG00000215474-SKOR2 [tissue]
Peptide AtlasQ2VWA4
IPIIPI00658068   IPI00886728   
Protein Interaction databases
DIP (DOE-UCLA)Q2VWA4
IntAct (EBI)Q2VWA4
FunCoupENSG00000215474
BioGRIDSKOR2
STRING (EMBL)SKOR2
ZODIACSKOR2
Ontologies - Pathways
QuickGOQ2VWA4
Ontology : AmiGOtranscription corepressor activity  nucleus  cytoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  negative regulation of transforming growth factor beta receptor signaling pathway  negative regulation of BMP signaling pathway  negative regulation of cell differentiation  SMAD binding  neuron development  negative regulation of nucleic acid-templated transcription  
Ontology : EGO-EBItranscription corepressor activity  nucleus  cytoplasm  transcription, DNA-templated  regulation of transcription, DNA-templated  negative regulation of transforming growth factor beta receptor signaling pathway  negative regulation of BMP signaling pathway  negative regulation of cell differentiation  SMAD binding  neuron development  negative regulation of nucleic acid-templated transcription  
NDEx NetworkSKOR2
Atlas of Cancer Signalling NetworkSKOR2
Wikipedia pathwaysSKOR2
Orthology - Evolution
OrthoDB652991
GeneTree (enSembl)ENSG00000215474
Phylogenetic Trees/Animal Genes : TreeFamSKOR2
HOVERGENQ2VWA4
HOGENOMQ2VWA4
Homologs : HomoloGeneSKOR2
Homology/Alignments : Family Browser (UCSC)SKOR2
Gene fusions - Rearrangements
Tumor Fusion PortalSKOR2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSKOR2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SKOR2
dbVarSKOR2
ClinVarSKOR2
1000_GenomesSKOR2 
Exome Variant ServerSKOR2
ExAC (Exome Aggregation Consortium)ENSG00000215474
GNOMAD BrowserENSG00000215474
Genetic variants : HAPMAP652991
Genomic Variants (DGV)SKOR2 [DGVbeta]
DECIPHERSKOR2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSKOR2 
Mutations
ICGC Data PortalSKOR2 
TCGA Data PortalSKOR2 
Broad Tumor PortalSKOR2
OASIS PortalSKOR2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSKOR2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSKOR2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SKOR2
DgiDB (Drug Gene Interaction Database)SKOR2
DoCM (Curated mutations)SKOR2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SKOR2 (select a term)
intoGenSKOR2
Cancer3DSKOR2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM617138   
Orphanet
DisGeNETSKOR2
MedgenSKOR2
Genetic Testing Registry SKOR2
NextProtQ2VWA4 [Medical]
TSGene652991
GENETestsSKOR2
Target ValidationSKOR2
Huge Navigator SKOR2 [HugePedia]
snp3D : Map Gene to Disease652991
BioCentury BCIQSKOR2
ClinGenSKOR2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD652991
Chemical/Pharm GKB GenePA165429121
Clinical trialSKOR2
Miscellaneous
canSAR (ICR)SKOR2 (select the gene name)
Probes
Litterature
PubMed7 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSKOR2
EVEXSKOR2
GoPubMedSKOR2
iHOPSKOR2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Nov 21 14:34:45 CET 2017

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