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SLC10A1 (solute carrier family 10 member 1)

Identity

Alias_namessolute carrier family 10 (sodium/bile acid cotransporter)
Alias_symbol (synonym)NTCP
Other alias
HGNC (Hugo) SLC10A1
LocusID (NCBI) 6554
Atlas_Id 46316
Location 14q24.1  [Link to chromosome band 14q24]
Location_base_pair Starts at 69775835 and ends at 69797289 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
NCOA6 (20q11.22) / SLC10A1 (14q24.2)NCOA6 20q11.22 / SLC10A1 14q24.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC10A1   10905
Cards
Entrez_Gene (NCBI)SLC10A1  6554  solute carrier family 10 member 1
AliasesNTCP
GeneCards (Weizmann)SLC10A1
Ensembl hg19 (Hinxton)ENSG00000100652 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000100652 [Gene_View]  chr14:69775835-69797289 [Contig_View]  SLC10A1 [Vega]
ICGC DataPortalENSG00000100652
TCGA cBioPortalSLC10A1
AceView (NCBI)SLC10A1
Genatlas (Paris)SLC10A1
WikiGenes6554
SOURCE (Princeton)SLC10A1
Genetics Home Reference (NIH)SLC10A1
Genomic and cartography
GoldenPath hg38 (UCSC)SLC10A1  -     chr14:69775835-69797289 -  14q24.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC10A1  -     14q24.1   [Description]    (hg19-Feb_2009)
EnsemblSLC10A1 - 14q24.1 [CytoView hg19]  SLC10A1 - 14q24.1 [CytoView hg38]
Mapping of homologs : NCBISLC10A1 [Mapview hg19]  SLC10A1 [Mapview hg38]
OMIM182396   
Gene and transcription
Genbank (Entrez)AK314028 AY544127 BC069799 BC069822 BC074724
RefSeq transcript (Entrez)NM_003049
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC10A1
Cluster EST : UnigeneHs.952 [ NCBI ]
CGAP (NCI)Hs.952
Alternative Splicing GalleryENSG00000100652
Gene ExpressionSLC10A1 [ NCBI-GEO ]   SLC10A1 [ EBI - ARRAY_EXPRESS ]   SLC10A1 [ SEEK ]   SLC10A1 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC10A1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6554
GTEX Portal (Tissue expression)SLC10A1
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ14973   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ14973  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ14973
Splice isoforms : SwissVarQ14973
PhosPhoSitePlusQ14973
Domains : Interpro (EBI)BilAc:Na_symport/Acr3    Bilac:Na_transpt    SLC10A1   
Domain families : Pfam (Sanger)SBF (PF01758)   
Domain families : Pfam (NCBI)pfam01758   
Conserved Domain (NCBI)SLC10A1
DMDM Disease mutations6554
Blocks (Seattle)SLC10A1
SuperfamilyQ14973
Human Protein AtlasENSG00000100652
Peptide AtlasQ14973
HPRD01672
IPIIPI00001637   
Protein Interaction databases
DIP (DOE-UCLA)Q14973
IntAct (EBI)Q14973
FunCoupENSG00000100652
BioGRIDSLC10A1
STRING (EMBL)SLC10A1
ZODIACSLC10A1
Ontologies - Pathways
QuickGOQ14973
Ontology : AmiGOvirus receptor activity  plasma membrane  integral component of plasma membrane  transport  sodium ion transport  bile acid:sodium symporter activity  bile acid:sodium symporter activity  bile acid and bile salt transport  bile acid and bile salt transport  basolateral plasma membrane  viral entry into host cell  transmembrane transport  
Ontology : EGO-EBIvirus receptor activity  plasma membrane  integral component of plasma membrane  transport  sodium ion transport  bile acid:sodium symporter activity  bile acid:sodium symporter activity  bile acid and bile salt transport  bile acid and bile salt transport  basolateral plasma membrane  viral entry into host cell  transmembrane transport  
Pathways : KEGGBile secretion   
NDEx NetworkSLC10A1
Atlas of Cancer Signalling NetworkSLC10A1
Wikipedia pathwaysSLC10A1
Orthology - Evolution
OrthoDB6554
GeneTree (enSembl)ENSG00000100652
Phylogenetic Trees/Animal Genes : TreeFamSLC10A1
HOVERGENQ14973
HOGENOMQ14973
Homologs : HomoloGeneSLC10A1
Homology/Alignments : Family Browser (UCSC)SLC10A1
Gene fusions - Rearrangements
Fusion : MitelmanNCOA6/SLC10A1 [20q11.22/14q24.2]  [t(14;20)(q24;q11)]  
Fusion: TCGANCOA6 20q11.22 SLC10A1 14q24.2 OV
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC10A1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC10A1
dbVarSLC10A1
ClinVarSLC10A1
1000_GenomesSLC10A1 
Exome Variant ServerSLC10A1
ExAC (Exome Aggregation Consortium)SLC10A1 (select the gene name)
Genetic variants : HAPMAP6554
Genomic Variants (DGV)SLC10A1 [DGVbeta]
DECIPHERSLC10A1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC10A1 
Mutations
ICGC Data PortalSLC10A1 
TCGA Data PortalSLC10A1 
Broad Tumor PortalSLC10A1
OASIS PortalSLC10A1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC10A1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC10A1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC10A1
DgiDB (Drug Gene Interaction Database)SLC10A1
DoCM (Curated mutations)SLC10A1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC10A1 (select a term)
intoGenSLC10A1
Cancer3DSLC10A1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM182396   
Orphanet
MedgenSLC10A1
Genetic Testing Registry SLC10A1
NextProtQ14973 [Medical]
TSGene6554
GENETestsSLC10A1
Huge Navigator SLC10A1 [HugePedia]
snp3D : Map Gene to Disease6554
BioCentury BCIQSLC10A1
ClinGenSLC10A1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6554
Chemical/Pharm GKB GenePA317
Clinical trialSLC10A1
Miscellaneous
canSAR (ICR)SLC10A1 (select the gene name)
Probes
Litterature
PubMed49 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC10A1
EVEXSLC10A1
GoPubMedSLC10A1
iHOPSLC10A1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri May 19 12:37:22 CEST 2017

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