Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool
Other Information
Locus ID:
NCBI: 6555
MIM: 601295
HGNC: 10906
Ensembl: ENSG00000125255
Variants:
dbSNP: 6555
ClinVar: 6555
TCGA: ENSG00000125255
COSMIC: SLC10A2
RNA/Proteins
| Gene ID | Transcript ID | Uniprot |
|---|---|---|
| ENSG00000125255 | ENST00000245312 | Q12908 |
Expression (GTEx)
Pathways
Protein levels (Protein atlas)
PharmGKB
| Entity ID | Name | Type | Evidence | Association | PK | PD | PMIDs |
|---|---|---|---|---|---|---|---|
| PA130620651 | anthracyclines and related substances | Chemical | ClinicalAnnotation | associated | PD | 21900104, 23441093 | |
| PA445062 | Neoplasms | Disease | ClinicalAnnotation | associated | PD | 21900104, 23441093 | |
| PA445425 | Prostatic Neoplasms | Disease | ClinicalAnnotation | associated | PD | 20038957 | |
| PA449383 | docetaxel | Chemical | ClinicalAnnotation | associated | PD | 20038957 | |
| PA451644 | thalidomide | Chemical | ClinicalAnnotation | associated | PD | 20038957 |
References
| Pubmed ID | Year | Title | Citations |
|---|---|---|---|
| 36410025 | 2023 | Loss of apical sodium bile acid transporter alters bile acid circulation and reduces biliary damage in cholangitis. | 2 |
| 36410025 | 2023 | Loss of apical sodium bile acid transporter alters bile acid circulation and reduces biliary damage in cholangitis. | 2 |
| 33189717 | 2021 | S-acylation status of bile acid transporter hASBT regulates its function, metabolic stability, membrane expression, and phosphorylation state. | 2 |
| 33278408 | 2021 | A Novel Fluorescence-Based Method to Evaluate Ileal Apical Sodium-Dependent Bile Acid Transporter ASBT. | 0 |
| 34638773 | 2021 | Placental Expression of Bile Acid Transporters in Intrahepatic Cholestasis of Pregnancy. | 6 |
| 33189717 | 2021 | S-acylation status of bile acid transporter hASBT regulates its function, metabolic stability, membrane expression, and phosphorylation state. | 2 |
| 33278408 | 2021 | A Novel Fluorescence-Based Method to Evaluate Ileal Apical Sodium-Dependent Bile Acid Transporter ASBT. | 0 |
| 34638773 | 2021 | Placental Expression of Bile Acid Transporters in Intrahepatic Cholestasis of Pregnancy. | 6 |
| 32071081 | 2020 | S-acylation modulates the function of the apical sodium-dependent bile acid transporter in human cells. | 5 |
| 32162131 | 2020 | Efficient SNP editing in haploid human pluripotent stem cells. | 3 |
| 32071081 | 2020 | S-acylation modulates the function of the apical sodium-dependent bile acid transporter in human cells. | 5 |
| 32162131 | 2020 | Efficient SNP editing in haploid human pluripotent stem cells. | 3 |
| 31194565 | 2019 | Tyrosine Phosphorylation Regulates Plasma Membrane Expression and Stability of the Human Bile Acid Transporter ASBT (SLC10A2). | 4 |
| 31623375 | 2019 | Mechanism of Dyslipidemia in Obesity-Unique Regulation of Ileal Villus Cell Brush Border Membrane Sodium-Bile Acid Cotransport. | 3 |
| 31194565 | 2019 | Tyrosine Phosphorylation Regulates Plasma Membrane Expression and Stability of the Human Bile Acid Transporter ASBT (SLC10A2). | 4 |
Citation
Dessen P
SLC10A2 (solute carrier family 10 member 2)
Atlas Genet Cytogenet Oncol Haematol. 2007-02-01
Online version: http://atlasgeneticsoncology.org/gene/43699/slc10a2
