SLC15A1 (solute carrier family 15 member 1)

2007-02-01  

Identity

HGNC
LOCATION
13q32.2
LOCUSID
ALIAS
HPECT1,HPEPT1,PEPT1

Other Information

Locus ID:

NCBI: 6564
MIM: 600544
HGNC: 10920
Ensembl: ENSG00000088386

Variants:

dbSNP: 6564
ClinVar: 6564
TCGA: ENSG00000088386
COSMIC: SLC15A1

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000088386ENST00000376503P46059
ENSG00000088386ENST00000376503B2CQT6

Expression (GTEx)

0
10
20
30
40
50
60

Pathways

PathwaySourceExternal ID
Protein digestion and absorptionKEGGko04974
Protein digestion and absorptionKEGGhsa04974
Transmembrane transport of small moleculesREACTOMER-HSA-382551
SLC-mediated transmembrane transportREACTOMER-HSA-425407
Transport of inorganic cations/anions and amino acids/oligopeptidesREACTOMER-HSA-425393
Proton/oligopeptide cotransportersREACTOMER-HSA-427975

Protein levels (Protein atlas)

Not detected
Low
Medium
High

PharmGKB

Entity IDNameTypeEvidenceAssociationPKPDPMIDs
PA133950441hmg coa reductase inhibitorsChemicalPathwayassociated
PA449688fluvastatinChemicalPathwayassociated

References

Pubmed IDYearTitleCitations
346379152022Expression, purification and characterization of human proton-coupled oligopeptide transporter 1 hPEPT1.0
355465032022Expression, Regulation, and Role of an Oligopeptide Transporter: PEPT1 in Tumors.0
346379152022Expression, purification and characterization of human proton-coupled oligopeptide transporter 1 hPEPT1.0
355465032022Expression, Regulation, and Role of an Oligopeptide Transporter: PEPT1 in Tumors.0
339528232021Protonation State of a Histidine Residue in Human Oligopeptide Transporter 1 (hPEPT1) Regulates hPEPT1-Mediated Efflux Activity.1
340313582021Epigenetic regulation of intestinal peptide transporter PEPT1 as a potential strategy for colorectal cancer sensitization.7
345696002021PEPT1 is essential for the growth of pancreatic cancer cells: a viable drug target.10
339528232021Protonation State of a Histidine Residue in Human Oligopeptide Transporter 1 (hPEPT1) Regulates hPEPT1-Mediated Efflux Activity.1
340313582021Epigenetic regulation of intestinal peptide transporter PEPT1 as a potential strategy for colorectal cancer sensitization.7
345696002021PEPT1 is essential for the growth of pancreatic cancer cells: a viable drug target.10
317574252020Alternate expression of PEPT1 and PEPT2 in epidermal differentiation is required for NOD2 immune responses by bacteria-derived muramyl dipeptide.1
317574252020Alternate expression of PEPT1 and PEPT2 in epidermal differentiation is required for NOD2 immune responses by bacteria-derived muramyl dipeptide.1
314544352019Association of SLC15A1 polymorphisms with susceptibility to dyslipidaemia in a Chinese Han population.5
314544352019Association of SLC15A1 polymorphisms with susceptibility to dyslipidaemia in a Chinese Han population.5
298908542018Dipeptide-modified nanoparticles to facilitate oral docetaxel delivery: new insights into PepT1-mediated targeting strategy.11

Citation

Dessen P

SLC15A1 (solute carrier family 15 member 1)

Atlas Genet Cytogenet Oncol Haematol. 2007-02-01

Online version: http://atlasgeneticsoncology.org/gene/46274/slc15a1