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SLC16A10 (solute carrier family 16 member 10)

Identity

Alias_namessolute carrier family 16 (monocarboxylic acid transporters), member 10
solute carrier family 16 (aromatic amino acid transporter), member 10
Alias_symbol (synonym)TAT1
MCT10
Other aliasPRO0813
HGNC (Hugo) SLC16A10
LocusID (NCBI) 117247
Atlas_Id 56852
Location 6q21  [Link to chromosome band 6q21]
Location_base_pair Starts at 111087503 and ends at 111231194 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TRMT11 (6q22.32) / SLC16A10 (6q21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(6;6)(q21;q22) TRMT11/SLC16A10

External links

Nomenclature
HGNC (Hugo)SLC16A10   17027
Cards
Entrez_Gene (NCBI)SLC16A10  117247  solute carrier family 16 member 10
AliasesMCT10; PRO0813; TAT1
GeneCards (Weizmann)SLC16A10
Ensembl hg19 (Hinxton)ENSG00000112394 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112394 [Gene_View]  ENSG00000112394 [Sequence]  chr6:111087503-111231194 [Contig_View]  SLC16A10 [Vega]
ICGC DataPortalENSG00000112394
TCGA cBioPortalSLC16A10
AceView (NCBI)SLC16A10
Genatlas (Paris)SLC16A10
WikiGenes117247
SOURCE (Princeton)SLC16A10
Genetics Home Reference (NIH)SLC16A10
Genomic and cartography
GoldenPath hg38 (UCSC)SLC16A10  -     chr6:111087503-111231194 +  6q21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC16A10  -     6q21   [Description]    (hg19-Feb_2009)
GoldenPathSLC16A10 - 6q21 [CytoView hg19]  SLC16A10 - 6q21 [CytoView hg38]
Genome Data Viewer NCBISLC16A10 [Mapview hg19]  
OMIM607550   
Gene and transcription
Genbank (Entrez)AB057445 AF116652 AK126183 AK172789 BC017968
RefSeq transcript (Entrez)NM_018593
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC16A10
Alternative Splicing GalleryENSG00000112394
Gene ExpressionSLC16A10 [ NCBI-GEO ]   SLC16A10 [ EBI - ARRAY_EXPRESS ]   SLC16A10 [ SEEK ]   SLC16A10 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC16A10 [ Firebrowse - Broad ]
GenevisibleExpression of SLC16A10 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)117247
GTEX Portal (Tissue expression)SLC16A10
Human Protein AtlasENSG00000112394-SLC16A10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TF71   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TF71  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TF71
Splice isoforms : SwissVarQ8TF71
PhosPhoSitePlusQ8TF71
Domaine pattern : Prosite (Expaxy)MFS (PS50850)   
Domains : Interpro (EBI)MCT10    MFS    MFS_dom    MFS_trans_sf   
Domain families : Pfam (Sanger)MFS_1 (PF07690)   
Domain families : Pfam (NCBI)pfam07690   
Conserved Domain (NCBI)SLC16A10
DMDM Disease mutations117247
SuperfamilyQ8TF71
Human Protein Atlas [tissue]ENSG00000112394-SLC16A10 [tissue]
Peptide AtlasQ8TF71
IPIIPI00152879   IPI00642983   IPI00807388   IPI00643442   IPI00647261   
Protein Interaction databases
DIP (DOE-UCLA)Q8TF71
IntAct (EBI)Q8TF71
FunCoupENSG00000112394
BioGRIDSLC16A10
STRING (EMBL)SLC16A10
ZODIACSLC16A10
Ontologies - Pathways
QuickGOQ8TF71
Ontology : AmiGOamino acid transmembrane transport  plasma membrane  integral component of plasma membrane  thyroid hormone generation  amino acid transport  amino acid transmembrane transporter activity  aromatic amino acid transmembrane transporter activity  thyroid hormone transmembrane transporter activity  monocarboxylic acid transport  aromatic amino acid transport  integral component of membrane  basolateral plasma membrane  cell junction  intracellular membrane-bounded organelle  thyroid hormone transport  thyroid-stimulating hormone secretion  
Ontology : EGO-EBIamino acid transmembrane transport  plasma membrane  integral component of plasma membrane  thyroid hormone generation  amino acid transport  amino acid transmembrane transporter activity  aromatic amino acid transmembrane transporter activity  thyroid hormone transmembrane transporter activity  monocarboxylic acid transport  aromatic amino acid transport  integral component of membrane  basolateral plasma membrane  cell junction  intracellular membrane-bounded organelle  thyroid hormone transport  thyroid-stimulating hormone secretion  
Pathways : KEGGThyroid hormone signaling pathway    Protein digestion and absorption   
NDEx NetworkSLC16A10
Atlas of Cancer Signalling NetworkSLC16A10
Wikipedia pathwaysSLC16A10
Orthology - Evolution
OrthoDB117247
GeneTree (enSembl)ENSG00000112394
Phylogenetic Trees/Animal Genes : TreeFamSLC16A10
HOGENOMQ8TF71
Homologs : HomoloGeneSLC16A10
Homology/Alignments : Family Browser (UCSC)SLC16A10
Gene fusions - Rearrangements
Fusion : QuiverSLC16A10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC16A10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC16A10
dbVarSLC16A10
ClinVarSLC16A10
1000_GenomesSLC16A10 
Exome Variant ServerSLC16A10
GNOMAD BrowserENSG00000112394
Varsome BrowserSLC16A10
Genetic variants : HAPMAP117247
Genomic Variants (DGV)SLC16A10 [DGVbeta]
DECIPHERSLC16A10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC16A10 
Mutations
ICGC Data PortalSLC16A10 
TCGA Data PortalSLC16A10 
Broad Tumor PortalSLC16A10
OASIS PortalSLC16A10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC16A10  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSLC16A10
Mutations and Diseases : HGMDSLC16A10
BioMutaselect SLC16A10
DgiDB (Drug Gene Interaction Database)SLC16A10
DoCM (Curated mutations)SLC16A10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC16A10 (select a term)
intoGenSLC16A10
Cancer3DSLC16A10 (select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607550   
Orphanet
DisGeNETSLC16A10
MedgenSLC16A10
Genetic Testing Registry SLC16A10
NextProtQ8TF71 [Medical]
TSGene117247
GENETestsSLC16A10
Open Targets GeneticsENSG00000112394  [validation]
snp3D : Map Gene to Disease117247
BioCentury BCIQSLC16A10
ClinGenSLC16A10
Clinical trials, drugs, therapy
Protein Interactions : CTD117247
Pharm GKB GenePA38197
Clinical trialSLC16A10
Miscellaneous
canSAR (ICR)SLC16A10 (select the gene name)
HarmonizomeSLC16A10
DataMed IndexSLC16A10
Probes
Litterature
PubMed26 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC16A10
EVEXSLC16A10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Jul 11 20:11:36 CEST 2020
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