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SLC16A10 (solute carrier family 16 member 10)

Identity

Alias (NCBI)MCT10
PRO0813
TAT1
HGNC (Hugo) SLC16A10
HGNC Alias symbTAT1
MCT10
HGNC Previous namesolute carrier family 16 (monocarboxylic acid transporters), member 10
 solute carrier family 16 (aromatic amino acid transporter), member 10
LocusID (NCBI) 117247
Atlas_Id 56852
Location 6q21  [Link to chromosome band 6q21]
Location_base_pair Starts at 111087503 and ends at 111231194 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
TRMT11 (6q22.32) / SLC16A10 (6q21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Leukemias implicated (Data extracted from papers in the Atlas) [ 1 ]
  Del(6q) in Chronic lymphocytic leukaemia (CLL)

External links

 

Nomenclature
HGNC (Hugo)SLC16A10   17027
Cards
Entrez_Gene (NCBI)SLC16A10    solute carrier family 16 member 10
AliasesMCT10; PRO0813; TAT1
GeneCards (Weizmann)SLC16A10
Ensembl hg19 (Hinxton)ENSG00000112394 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000112394 [Gene_View]  ENSG00000112394 [Sequence]  chr6:111087503-111231194 [Contig_View]  SLC16A10 [Vega]
ICGC DataPortalENSG00000112394
TCGA cBioPortalSLC16A10
AceView (NCBI)SLC16A10
Genatlas (Paris)SLC16A10
SOURCE (Princeton)SLC16A10
Genetics Home Reference (NIH)SLC16A10
Genomic and cartography
GoldenPath hg38 (UCSC)SLC16A10  -     chr6:111087503-111231194 +  6q21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC16A10  -     6q21   [Description]    (hg19-Feb_2009)
GoldenPathSLC16A10 - 6q21 [CytoView hg19]  SLC16A10 - 6q21 [CytoView hg38]
ImmunoBaseENSG00000112394
Genome Data Viewer NCBISLC16A10 [Mapview hg19]  
OMIM607550   
Gene and transcription
Genbank (Entrez)AB057445 AF116652 AK126183 AK172789 BC017968
RefSeq transcript (Entrez)NM_018593
Consensus coding sequences : CCDS (NCBI)SLC16A10
Gene ExpressionSLC16A10 [ NCBI-GEO ]   SLC16A10 [ EBI - ARRAY_EXPRESS ]   SLC16A10 [ SEEK ]   SLC16A10 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC16A10 [ Firebrowse - Broad ]
GenevisibleExpression of SLC16A10 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)117247
GTEX Portal (Tissue expression)SLC16A10
Human Protein AtlasENSG00000112394-SLC16A10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TF71   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TF71  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TF71
PhosPhoSitePlusQ8TF71
Domaine pattern : Prosite (Expaxy)MFS (PS50850)   
Domains : Interpro (EBI)MCT10    MFS    MFS_dom    MFS_trans_sf   
Domain families : Pfam (Sanger)MFS_1 (PF07690)   
Domain families : Pfam (NCBI)pfam07690   
Conserved Domain (NCBI)SLC16A10
SuperfamilyQ8TF71
AlphaFold pdb e-kbQ8TF71   
Human Protein Atlas [tissue]ENSG00000112394-SLC16A10 [tissue]
Protein Interaction databases
DIP (DOE-UCLA)Q8TF71
IntAct (EBI)Q8TF71
BioGRIDSLC16A10
STRING (EMBL)SLC16A10
ZODIACSLC16A10
Ontologies - Pathways
QuickGOQ8TF71
Ontology : AmiGOprotein binding  plasma membrane  integral component of plasma membrane  thyroid hormone generation  amino acid transport  aromatic amino acid transmembrane transporter activity  thyroid hormone transmembrane transporter activity  aromatic amino acid transport  integral component of membrane  basolateral plasma membrane  basolateral plasma membrane  cell junction  intracellular membrane-bounded organelle  transmembrane transport  thyroid hormone transport  thyroid-stimulating hormone secretion  
Ontology : EGO-EBIprotein binding  plasma membrane  integral component of plasma membrane  thyroid hormone generation  amino acid transport  aromatic amino acid transmembrane transporter activity  thyroid hormone transmembrane transporter activity  aromatic amino acid transport  integral component of membrane  basolateral plasma membrane  basolateral plasma membrane  cell junction  intracellular membrane-bounded organelle  transmembrane transport  thyroid hormone transport  thyroid-stimulating hormone secretion  
Pathways : KEGGThyroid hormone signaling pathway    Protein digestion and absorption   
NDEx NetworkSLC16A10
Atlas of Cancer Signalling NetworkSLC16A10
Wikipedia pathwaysSLC16A10
Orthology - Evolution
OrthoDB117247
GeneTree (enSembl)ENSG00000112394
Phylogenetic Trees/Animal Genes : TreeFamSLC16A10
Homologs : HomoloGeneSLC16A10
Homology/Alignments : Family Browser (UCSC)SLC16A10
Gene fusions - Rearrangements
Fusion : QuiverSLC16A10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC16A10 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC16A10
dbVarSLC16A10
ClinVarSLC16A10
MonarchSLC16A10
1000_GenomesSLC16A10 
Exome Variant ServerSLC16A10
GNOMAD BrowserENSG00000112394
Varsome BrowserSLC16A10
ACMGSLC16A10 variants
VarityQ8TF71
Genomic Variants (DGV)SLC16A10 [DGVbeta]
DECIPHERSLC16A10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC16A10 
Mutations
ICGC Data PortalSLC16A10 
TCGA Data PortalSLC16A10 
Broad Tumor PortalSLC16A10
OASIS PortalSLC16A10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC16A10  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSLC16A10
Mutations and Diseases : HGMDSLC16A10
LOVD (Leiden Open Variation Database)[gene] [transcripts] [variants]
BioMutaSLC16A10
DgiDB (Drug Gene Interaction Database)SLC16A10
DoCM (Curated mutations)SLC16A10
CIViC (Clinical Interpretations of Variants in Cancer)SLC16A10
Cancer3DSLC16A10
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607550   
Orphanet
DisGeNETSLC16A10
MedgenSLC16A10
Genetic Testing Registry SLC16A10
NextProtQ8TF71 [Medical]
GENETestsSLC16A10
Target ValidationSLC16A10
Huge Navigator SLC16A10 [HugePedia]
ClinGenSLC16A10
Clinical trials, drugs, therapy
MyCancerGenomeSLC16A10
Protein Interactions : CTDSLC16A10
Pharm GKB GenePA38197
PharosQ8TF71
Clinical trialSLC16A10
Miscellaneous
canSAR (ICR)SLC16A10
HarmonizomeSLC16A10
DataMed IndexSLC16A10
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
EVEXSLC16A10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Oct 4 15:31:23 CEST 2021
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