Atlas of Genetics and Cytogenetics in Oncology and Haematology

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SLC16A7 (solute carrier family 16 member 7)

Identity

Alias_namessolute carrier family 16 (monocarboxylic acid transporters), member 7
solute carrier family 16 (monocarboxylate transporter), member 7
Alias_symbol (synonym)MCT2
Other alias
HGNC (Hugo) SLC16A7
LocusID (NCBI) 9194
Atlas_Id 50149
Location 12q14.1  [Link to chromosome band 12q14]
Location_base_pair Starts at 59689337 and ends at 59789854 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SLC16A7 (12q14.1) / CALCOCO1 (12q13.13)SLC16A7 (12q14.1) / MUCL1 (12q13.2)SLC16A7 (12q14.1) / RP11-362K2.2 ()
SLC16A7 (12q14.1) / TTC28 (22q12.1)SLC16A7 12q14.1 RP11-362K2.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 5 ]
  Lung: Translocations in Adenocarcinoma
Lung: Translocations in Squamous Cell Carcinoma
t(12;12)(q13;q14) SLC16A7/CALCOCO1
t(12;12)(q13;q14) SLC16A7/MUCL1
t(12;22)(q14;q12) SLC16A7/TTC28

External links

Nomenclature
HGNC (Hugo)SLC16A7   10928
Cards
Entrez_Gene (NCBI)SLC16A7  9194  solute carrier family 16 member 7
AliasesMCT2
GeneCards (Weizmann)SLC16A7
Ensembl hg19 (Hinxton)ENSG00000118596 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000118596 [Gene_View]  ENSG00000118596 [Sequence]  chr12:59689337-59789854 [Contig_View]  SLC16A7 [Vega]
ICGC DataPortalENSG00000118596
TCGA cBioPortalSLC16A7
AceView (NCBI)SLC16A7
Genatlas (Paris)SLC16A7
WikiGenes9194
SOURCE (Princeton)SLC16A7
Genetics Home Reference (NIH)SLC16A7
Genomic and cartography
GoldenPath hg38 (UCSC)SLC16A7  -     chr12:59689337-59789854 +  12q14.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC16A7  -     12q14.1   [Description]    (hg19-Feb_2009)
EnsemblSLC16A7 - 12q14.1 [CytoView hg19]  SLC16A7 - 12q14.1 [CytoView hg38]
Mapping of homologs : NCBISLC16A7 [Mapview hg19]  SLC16A7 [Mapview hg38]
OMIM603654   
Gene and transcription
Genbank (Entrez)AF049608 AF058056 AK301725 AK310281 AK313345
RefSeq transcript (Entrez)NM_001270622 NM_001270623 NM_004731
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC16A7
Cluster EST : UnigeneHs.439643 [ NCBI ]
CGAP (NCI)Hs.439643
Alternative Splicing GalleryENSG00000118596
Gene ExpressionSLC16A7 [ NCBI-GEO ]   SLC16A7 [ EBI - ARRAY_EXPRESS ]   SLC16A7 [ SEEK ]   SLC16A7 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC16A7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9194
GTEX Portal (Tissue expression)SLC16A7
Human Protein AtlasENSG00000118596-SLC16A7 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO60669   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO60669  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO60669
Splice isoforms : SwissVarO60669
PhosPhoSitePlusO60669
Domaine pattern : Prosite (Expaxy)MFS (PS50850)   
Domains : Interpro (EBI)MCT    MCT2    MFS    MFS_dom    MFS_trans_sf   
Domain families : Pfam (Sanger)MFS_1 (PF07690)   
Domain families : Pfam (NCBI)pfam07690   
Conserved Domain (NCBI)SLC16A7
DMDM Disease mutations9194
Blocks (Seattle)SLC16A7
SuperfamilyO60669
Human Protein Atlas [tissue]ENSG00000118596-SLC16A7 [tissue]
Peptide AtlasO60669
HPRD06791
IPIIPI00171614   IPI01009836   IPI01022359   IPI01021272   IPI01022657   IPI01022797   IPI01020948   IPI01021218   IPI01021658   IPI01021802   
Protein Interaction databases
DIP (DOE-UCLA)O60669
IntAct (EBI)O60669
FunCoupENSG00000118596
BioGRIDSLC16A7
STRING (EMBL)SLC16A7
ZODIACSLC16A7
Ontologies - Pathways
QuickGOO60669
Ontology : AmiGOpyruvate secondary active transmembrane transporter activity  plasma membrane  integral component of plasma membrane  integral component of plasma membrane  monocarboxylic acid transmembrane transporter activity  monocarboxylic acid transmembrane transporter activity  lactate transmembrane transporter activity  symporter activity  monocarboxylic acid transport  lactate transmembrane transport  pyruvate transmembrane transporter activity  pyruvate transmembrane transport  
Ontology : EGO-EBIpyruvate secondary active transmembrane transporter activity  plasma membrane  integral component of plasma membrane  integral component of plasma membrane  monocarboxylic acid transmembrane transporter activity  monocarboxylic acid transmembrane transporter activity  lactate transmembrane transporter activity  symporter activity  monocarboxylic acid transport  lactate transmembrane transport  pyruvate transmembrane transporter activity  pyruvate transmembrane transport  
NDEx NetworkSLC16A7
Atlas of Cancer Signalling NetworkSLC16A7
Wikipedia pathwaysSLC16A7
Orthology - Evolution
OrthoDB9194
GeneTree (enSembl)ENSG00000118596
Phylogenetic Trees/Animal Genes : TreeFamSLC16A7
HOGENOMO60669
Homologs : HomoloGeneSLC16A7
Homology/Alignments : Family Browser (UCSC)SLC16A7
Gene fusions - Rearrangements
Fusion : MitelmanSLC16A7/CALCOCO1 [12q14.1/12q13.13]  
Fusion : MitelmanSLC16A7/MUCL1 [12q14.1/12q13.2]  [t(12;12)(q13;q14)]  
Fusion : MitelmanSLC16A7/TTC28 [12q14.1/22q12.1]  [t(12;22)(q14;q12)]  
Fusion PortalSLC16A7 12q14.1 RP11-362K2.2 GBM
Fusion : QuiverSLC16A7
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC16A7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC16A7
dbVarSLC16A7
ClinVarSLC16A7
1000_GenomesSLC16A7 
Exome Variant ServerSLC16A7
ExAC (Exome Aggregation Consortium)ENSG00000118596
GNOMAD BrowserENSG00000118596
Varsome BrowserSLC16A7
Genetic variants : HAPMAP9194
Genomic Variants (DGV)SLC16A7 [DGVbeta]
DECIPHERSLC16A7 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC16A7 
Mutations
ICGC Data PortalSLC16A7 
TCGA Data PortalSLC16A7 
Broad Tumor PortalSLC16A7
OASIS PortalSLC16A7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC16A7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC16A7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC16A7
DgiDB (Drug Gene Interaction Database)SLC16A7
DoCM (Curated mutations)SLC16A7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC16A7 (select a term)
intoGenSLC16A7
Cancer3DSLC16A7(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603654   
Orphanet
DisGeNETSLC16A7
MedgenSLC16A7
Genetic Testing Registry SLC16A7
NextProtO60669 [Medical]
TSGene9194
GENETestsSLC16A7
Target ValidationSLC16A7
Huge Navigator SLC16A7 [HugePedia]
snp3D : Map Gene to Disease9194
BioCentury BCIQSLC16A7
ClinGenSLC16A7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9194
Chemical/Pharm GKB GenePA35819
Clinical trialSLC16A7
Miscellaneous
canSAR (ICR)SLC16A7 (select the gene name)
DataMed IndexSLC16A7
Probes
Litterature
PubMed35 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC16A7
EVEXSLC16A7
GoPubMedSLC16A7
iHOPSLC16A7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Jan 17 18:38:18 CET 2019
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