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SLC17A6 (solute carrier family 17 member 6)

Identity

Alias_namessolute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6
solute carrier family 17 (vesicular glutamate transporter), member 6
Alias_symbol (synonym)DNPI
VGLUT2
Other alias
HGNC (Hugo) SLC17A6
LocusID (NCBI) 57084
Atlas_Id 73304
Location 11p14.3  [Link to chromosome band 11p14]
Location_base_pair Starts at 22338121 and ends at 22379500 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC17A6   16703
Cards
Entrez_Gene (NCBI)SLC17A6  57084  solute carrier family 17 member 6
AliasesDNPI; VGLUT2
GeneCards (Weizmann)SLC17A6
Ensembl hg19 (Hinxton)ENSG00000091664 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000091664 [Gene_View]  chr11:22338121-22379500 [Contig_View]  SLC17A6 [Vega]
ICGC DataPortalENSG00000091664
TCGA cBioPortalSLC17A6
AceView (NCBI)SLC17A6
Genatlas (Paris)SLC17A6
WikiGenes57084
SOURCE (Princeton)SLC17A6
Genetics Home Reference (NIH)SLC17A6
Genomic and cartography
GoldenPath hg38 (UCSC)SLC17A6  -     chr11:22338121-22379500 +  11p14.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC17A6  -     11p14.3   [Description]    (hg19-Feb_2009)
EnsemblSLC17A6 - 11p14.3 [CytoView hg19]  SLC17A6 - 11p14.3 [CytoView hg38]
Mapping of homologs : NCBISLC17A6 [Mapview hg19]  SLC17A6 [Mapview hg38]
OMIM607563   
Gene and transcription
Genbank (Entrez)AB032435 AK294502 AK309131 BC069629 BC069640
RefSeq transcript (Entrez)NM_020346
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC17A6
Cluster EST : UnigeneHs.242821 [ NCBI ]
CGAP (NCI)Hs.242821
Alternative Splicing GalleryENSG00000091664
Gene ExpressionSLC17A6 [ NCBI-GEO ]   SLC17A6 [ EBI - ARRAY_EXPRESS ]   SLC17A6 [ SEEK ]   SLC17A6 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC17A6 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57084
GTEX Portal (Tissue expression)SLC17A6
Human Protein AtlasENSG00000091664-SLC17A6 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9P2U8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9P2U8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9P2U8
Splice isoforms : SwissVarQ9P2U8
PhosPhoSitePlusQ9P2U8
Domaine pattern : Prosite (Expaxy)MFS (PS50850)   
Domains : Interpro (EBI)MFS    MFS_dom   
Domain families : Pfam (Sanger)MFS_1 (PF07690)   
Domain families : Pfam (NCBI)pfam07690   
Conserved Domain (NCBI)SLC17A6
DMDM Disease mutations57084
Blocks (Seattle)SLC17A6
SuperfamilyQ9P2U8
Human Protein Atlas [tissue]ENSG00000091664-SLC17A6 [tissue]
Peptide AtlasQ9P2U8
HPRD10459
IPIIPI00477420   IPI01013726   
Protein Interaction databases
DIP (DOE-UCLA)Q9P2U8
IntAct (EBI)Q9P2U8
FunCoupENSG00000091664
BioGRIDSLC17A6
STRING (EMBL)SLC17A6
ZODIACSLC17A6
Ontologies - Pathways
QuickGOQ9P2U8
Ontology : AmiGOL-glutamate transmembrane transporter activity  L-glutamate transmembrane transporter activity  ion transport  sodium ion transport  symporter activity  integral component of membrane  cell junction  synaptic vesicle membrane  synaptic vesicle membrane  neuron projection  L-glutamate transmembrane transport  neurotransmitter loading into synaptic vesicle  
Ontology : EGO-EBIL-glutamate transmembrane transporter activity  L-glutamate transmembrane transporter activity  ion transport  sodium ion transport  symporter activity  integral component of membrane  cell junction  synaptic vesicle membrane  synaptic vesicle membrane  neuron projection  L-glutamate transmembrane transport  neurotransmitter loading into synaptic vesicle  
Pathways : KEGGSynaptic vesicle cycle    Retrograde endocannabinoid signaling    Glutamatergic synapse    Nicotine addiction   
NDEx NetworkSLC17A6
Atlas of Cancer Signalling NetworkSLC17A6
Wikipedia pathwaysSLC17A6
Orthology - Evolution
OrthoDB57084
GeneTree (enSembl)ENSG00000091664
Phylogenetic Trees/Animal Genes : TreeFamSLC17A6
HOVERGENQ9P2U8
HOGENOMQ9P2U8
Homologs : HomoloGeneSLC17A6
Homology/Alignments : Family Browser (UCSC)SLC17A6
Gene fusions - Rearrangements
Tumor Fusion PortalSLC17A6
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC17A6 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC17A6
dbVarSLC17A6
ClinVarSLC17A6
1000_GenomesSLC17A6 
Exome Variant ServerSLC17A6
ExAC (Exome Aggregation Consortium)ENSG00000091664
GNOMAD BrowserENSG00000091664
Genetic variants : HAPMAP57084
Genomic Variants (DGV)SLC17A6 [DGVbeta]
DECIPHERSLC17A6 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC17A6 
Mutations
ICGC Data PortalSLC17A6 
TCGA Data PortalSLC17A6 
Broad Tumor PortalSLC17A6
OASIS PortalSLC17A6 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC17A6  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC17A6
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC17A6
DgiDB (Drug Gene Interaction Database)SLC17A6
DoCM (Curated mutations)SLC17A6 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC17A6 (select a term)
intoGenSLC17A6
Cancer3DSLC17A6(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607563   
Orphanet
DisGeNETSLC17A6
MedgenSLC17A6
Genetic Testing Registry SLC17A6
NextProtQ9P2U8 [Medical]
TSGene57084
GENETestsSLC17A6
Target ValidationSLC17A6
Huge Navigator SLC17A6 [HugePedia]
snp3D : Map Gene to Disease57084
BioCentury BCIQSLC17A6
ClinGenSLC17A6
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57084
Chemical/Pharm GKB GenePA424
Clinical trialSLC17A6
Miscellaneous
canSAR (ICR)SLC17A6 (select the gene name)
Probes
Litterature
PubMed25 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC17A6
EVEXSLC17A6
GoPubMedSLC17A6
iHOPSLC17A6
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Nov 20 20:12:14 CET 2017

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