Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SLC17A7 (solute carrier family 17 (vesicular glutamate transporter), member 7)

Identity

Alias_namessolute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
solute carrier family 17 (vesicular glutamate transporter), member 7
Alias_symbol (synonym)BNPI
VGLUT1
Other alias
HGNC (Hugo) SLC17A7
LocusID (NCBI) 57030
Atlas_Id 73305
Location 19q13.33  [Link to chromosome band 19q13]
Location_base_pair Starts at 49932655 and ends at 49944808 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
PALM3 (19p13.12) / SLC17A7 (19q13.33)SLC17A7 (19q13.33) / FHIT (3p14.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC17A7   16704
Cards
Entrez_Gene (NCBI)SLC17A7  57030  solute carrier family 17 (vesicular glutamate transporter), member 7
AliasesBNPI; VGLUT1
GeneCards (Weizmann)SLC17A7
Ensembl hg19 (Hinxton)ENSG00000104888 [Gene_View]  chr19:49932655-49944808 [Contig_View]  SLC17A7 [Vega]
Ensembl hg38 (Hinxton)ENSG00000104888 [Gene_View]  chr19:49932655-49944808 [Contig_View]  SLC17A7 [Vega]
ICGC DataPortalENSG00000104888
TCGA cBioPortalSLC17A7
AceView (NCBI)SLC17A7
Genatlas (Paris)SLC17A7
WikiGenes57030
SOURCE (Princeton)SLC17A7
Genetics Home Reference (NIH)SLC17A7
Genomic and cartography
GoldenPath hg19 (UCSC)SLC17A7  -     chr19:49932655-49944808 -  19q13.33   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SLC17A7  -     19q13.33   [Description]    (hg38-Dec_2013)
EnsemblSLC17A7 - 19q13.33 [CytoView hg19]  SLC17A7 - 19q13.33 [CytoView hg38]
Mapping of homologs : NCBISLC17A7 [Mapview hg19]  SLC17A7 [Mapview hg38]
OMIM605208   
Gene and transcription
Genbank (Entrez)AB032436 AK057879 AK091061 AK095659 AK289622
RefSeq transcript (Entrez)NM_020309
RefSeq genomic (Entrez)NC_000019 NC_018930 NT_011109 NW_004929415
Consensus coding sequences : CCDS (NCBI)SLC17A7
Cluster EST : UnigeneHs.375616 [ NCBI ]
CGAP (NCI)Hs.375616
Alternative Splicing GalleryENSG00000104888
Gene ExpressionSLC17A7 [ NCBI-GEO ]   SLC17A7 [ EBI - ARRAY_EXPRESS ]   SLC17A7 [ SEEK ]   SLC17A7 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC17A7 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57030
GTEX Portal (Tissue expression)SLC17A7
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9P2U7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9P2U7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9P2U7
Splice isoforms : SwissVarQ9P2U7
PhosPhoSitePlusQ9P2U7
Domaine pattern : Prosite (Expaxy)MFS (PS50850)   
Domains : Interpro (EBI)MFS    MFS_dom   
Domain families : Pfam (Sanger)MFS_1 (PF07690)   
Domain families : Pfam (NCBI)pfam07690   
Conserved Domain (NCBI)SLC17A7
DMDM Disease mutations57030
Blocks (Seattle)SLC17A7
SuperfamilyQ9P2U7
Human Protein AtlasENSG00000104888
Peptide AtlasQ9P2U7
HPRD05551
IPIIPI00025331   IPI01013431   
Protein Interaction databases
DIP (DOE-UCLA)Q9P2U7
IntAct (EBI)Q9P2U7
FunCoupENSG00000104888
BioGRIDSLC17A7
STRING (EMBL)SLC17A7
ZODIACSLC17A7
Ontologies - Pathways
QuickGOQ9P2U7
Ontology : AmiGOL-glutamate transmembrane transporter activity  inorganic phosphate transmembrane transporter activity  plasma membrane  ion transport  phosphate ion transport  synaptic transmission  neurotransmitter secretion  long-term memory  glutamate secretion  sodium:inorganic phosphate symporter activity  sodium-dependent phosphate transmembrane transporter activity  integral component of membrane  cell junction  synaptic vesicle membrane  synaptic vesicle membrane  synaptic transmission, glutamatergic  phosphate ion transmembrane transport  sodium ion transmembrane transport  sequestering of neurotransmitter  cerebellar mossy fiber  sodium-dependent phosphate transport  presynaptic active zone  L-glutamate import  transmembrane transport  excitatory synapse  regulation of excitatory postsynaptic membrane potential  clathrin-sculpted glutamate transport vesicle membrane  L-glutamate transmembrane transport  
Ontology : EGO-EBIL-glutamate transmembrane transporter activity  inorganic phosphate transmembrane transporter activity  plasma membrane  ion transport  phosphate ion transport  synaptic transmission  neurotransmitter secretion  long-term memory  glutamate secretion  sodium:inorganic phosphate symporter activity  sodium-dependent phosphate transmembrane transporter activity  integral component of membrane  cell junction  synaptic vesicle membrane  synaptic vesicle membrane  synaptic transmission, glutamatergic  phosphate ion transmembrane transport  sodium ion transmembrane transport  sequestering of neurotransmitter  cerebellar mossy fiber  sodium-dependent phosphate transport  presynaptic active zone  L-glutamate import  transmembrane transport  excitatory synapse  regulation of excitatory postsynaptic membrane potential  clathrin-sculpted glutamate transport vesicle membrane  L-glutamate transmembrane transport  
Pathways : KEGGSynaptic vesicle cycle    Retrograde endocannabinoid signaling    Glutamatergic synapse    Nicotine addiction   
NDEx NetworkSLC17A7
Atlas of Cancer Signalling NetworkSLC17A7
Wikipedia pathwaysSLC17A7
Orthology - Evolution
OrthoDB57030
GeneTree (enSembl)ENSG00000104888
Phylogenetic Trees/Animal Genes : TreeFamSLC17A7
HOVERGENQ9P2U7
HOGENOMQ9P2U7
Homologs : HomoloGeneSLC17A7
Homology/Alignments : Family Browser (UCSC)SLC17A7
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC17A7 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC17A7
dbVarSLC17A7
ClinVarSLC17A7
1000_GenomesSLC17A7 
Exome Variant ServerSLC17A7
ExAC (Exome Aggregation Consortium)SLC17A7 (select the gene name)
Genetic variants : HAPMAP57030
Genomic Variants (DGV)SLC17A7 [DGVbeta]
DECIPHER (Syndromes)19:49932655-49944808  ENSG00000104888
CONAN: Copy Number AnalysisSLC17A7 
Mutations
ICGC Data PortalSLC17A7 
TCGA Data PortalSLC17A7 
Broad Tumor PortalSLC17A7
OASIS PortalSLC17A7 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC17A7  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC17A7
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC17A7
DgiDB (Drug Gene Interaction Database)SLC17A7
DoCM (Curated mutations)SLC17A7 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC17A7 (select a term)
intoGenSLC17A7
Cancer3DSLC17A7(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM605208   
Orphanet
MedgenSLC17A7
Genetic Testing Registry SLC17A7
NextProtQ9P2U7 [Medical]
TSGene57030
GENETestsSLC17A7
Huge Navigator SLC17A7 [HugePedia]
snp3D : Map Gene to Disease57030
BioCentury BCIQSLC17A7
ClinGenSLC17A7
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57030
Chemical/Pharm GKB GenePA423
Clinical trialSLC17A7
Miscellaneous
canSAR (ICR)SLC17A7 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC17A7
EVEXSLC17A7
GoPubMedSLC17A7
iHOPSLC17A7
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:43:22 CET 2017

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.