Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC19A1 (solute carrier family 19 member 1)

Identity

Alias_namessolute carrier family 19 (folate transporter)
Alias_symbol (synonym)FOLT
Other aliasCHMD
IFC1
REFC
RFC1
HGNC (Hugo) SLC19A1
LocusID (NCBI) 6573
Atlas_Id 42311
Location 21q22.3  [Link to chromosome band 21q22]
Location_base_pair Starts at 46934629 and ends at 46962385 bp from pter ( according to hg19-Feb_2009)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC19A1   10937
Cards
Entrez_Gene (NCBI)SLC19A1  6573  solute carrier family 19 member 1
AliasesCHMD; FOLT; IFC1; REFC; 
RFC1
GeneCards (Weizmann)SLC19A1
Ensembl hg19 (Hinxton)ENSG00000173638 [Gene_View]  chr21:46934629-46962385 [Contig_View]  SLC19A1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000173638 [Gene_View]  chr21:46934629-46962385 [Contig_View]  SLC19A1 [Vega]
ICGC DataPortalENSG00000173638
TCGA cBioPortalSLC19A1
AceView (NCBI)SLC19A1
Genatlas (Paris)SLC19A1
WikiGenes6573
SOURCE (Princeton)SLC19A1
Genetics Home Reference (NIH)SLC19A1
Genomic and cartography
GoldenPath hg19 (UCSC)SLC19A1  -     chr21:46934629-46962385 -  21q22.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SLC19A1  -     21q22.3   [Description]    (hg38-Dec_2013)
EnsemblSLC19A1 - 21q22.3 [CytoView hg19]  SLC19A1 - 21q22.3 [CytoView hg38]
Mapping of homologs : NCBISLC19A1 [Mapview hg19]  SLC19A1 [Mapview hg38]
OMIM600424   
Gene and transcription
Genbank (Entrez)AB209069 AF004354 AK303168 AK307623 AK310797
RefSeq transcript (Entrez)NM_001205206 NM_001205207 NM_003056 NM_194255
RefSeq genomic (Entrez)NC_000021 NC_018932 NG_028278 NT_011512 NW_004929427
Consensus coding sequences : CCDS (NCBI)SLC19A1
Cluster EST : UnigeneHs.736903 [ NCBI ]
CGAP (NCI)Hs.736903
Alternative Splicing GalleryENSG00000173638
Gene ExpressionSLC19A1 [ NCBI-GEO ]   SLC19A1 [ EBI - ARRAY_EXPRESS ]   SLC19A1 [ SEEK ]   SLC19A1 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC19A1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6573
GTEX Portal (Tissue expression)SLC19A1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP41440   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP41440  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP41440
Splice isoforms : SwissVarP41440
PhosPhoSitePlusP41440
Domains : Interpro (EBI)Folate_carrier    MFS_dom    RFC   
Domain families : Pfam (Sanger)Folate_carrier (PF01770)   
Domain families : Pfam (NCBI)pfam01770   
Conserved Domain (NCBI)SLC19A1
DMDM Disease mutations6573
Blocks (Seattle)SLC19A1
SuperfamilyP41440
Human Protein AtlasENSG00000173638
Peptide AtlasP41440
HPRD02691
IPIIPI00375452   IPI00556340   IPI00978143   IPI00748975   IPI00789082   IPI00790970   IPI01012418   
Protein Interaction databases
DIP (DOE-UCLA)P41440
IntAct (EBI)P41440
FunCoupENSG00000173638
BioGRIDSLC19A1
STRING (EMBL)SLC19A1
ZODIACSLC19A1
Ontologies - Pathways
QuickGOP41440
Ontology : AmiGOfolic acid binding  plasma membrane  integral component of plasma membrane  female pregnancy  folic acid transporter activity  folic acid transporter activity  reduced folate carrier activity  methotrexate transporter activity  folic acid transport  basolateral plasma membrane  apical plasma membrane  brush border membrane  folic acid metabolic process  methotrexate transport  reduced folate transmembrane transport  
Ontology : EGO-EBIfolic acid binding  plasma membrane  integral component of plasma membrane  female pregnancy  folic acid transporter activity  folic acid transporter activity  reduced folate carrier activity  methotrexate transporter activity  folic acid transport  basolateral plasma membrane  apical plasma membrane  brush border membrane  folic acid metabolic process  methotrexate transport  reduced folate transmembrane transport  
Pathways : KEGGVitamin digestion and absorption   
NDEx NetworkSLC19A1
Atlas of Cancer Signalling NetworkSLC19A1
Wikipedia pathwaysSLC19A1
Orthology - Evolution
OrthoDB6573
GeneTree (enSembl)ENSG00000173638
Phylogenetic Trees/Animal Genes : TreeFamSLC19A1
HOVERGENP41440
HOGENOMP41440
Homologs : HomoloGeneSLC19A1
Homology/Alignments : Family Browser (UCSC)SLC19A1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC19A1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC19A1
dbVarSLC19A1
ClinVarSLC19A1
1000_GenomesSLC19A1 
Exome Variant ServerSLC19A1
ExAC (Exome Aggregation Consortium)SLC19A1 (select the gene name)
Genetic variants : HAPMAP6573
Genomic Variants (DGV)SLC19A1 [DGVbeta]
DECIPHER (Syndromes)21:46934629-46962385  ENSG00000173638
CONAN: Copy Number AnalysisSLC19A1 
Mutations
ICGC Data PortalSLC19A1 
TCGA Data PortalSLC19A1 
Broad Tumor PortalSLC19A1
OASIS PortalSLC19A1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC19A1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC19A1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC19A1
DgiDB (Drug Gene Interaction Database)SLC19A1
DoCM (Curated mutations)SLC19A1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC19A1 (select a term)
intoGenSLC19A1
Cancer3DSLC19A1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600424   
Orphanet23064   
MedgenSLC19A1
Genetic Testing Registry SLC19A1
NextProtP41440 [Medical]
TSGene6573
GENETestsSLC19A1
Huge Navigator SLC19A1 [HugePedia]
snp3D : Map Gene to Disease6573
BioCentury BCIQSLC19A1
ClinGenSLC19A1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6573
Chemical/Pharm GKB GenePA327
Clinical trialSLC19A1
Miscellaneous
canSAR (ICR)SLC19A1 (select the gene name)
Probes
Litterature
PubMed163 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC19A1
EVEXSLC19A1
GoPubMedSLC19A1
iHOPSLC19A1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Thu Mar 30 15:19:30 CEST 2017

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