Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC1A4 (solute carrier family 1 member 4)

Identity

Alias_namessolute carrier family 1 (glutamate/neutral amino acid transporter), member 4
Alias_symbol (synonym)SATT
ASCT1
Other aliasSPATCCM
HGNC (Hugo) SLC1A4
LocusID (NCBI) 6509
Atlas_Id 73311
Location 2p14  [Link to chromosome band 2p14]
Location_base_pair Starts at 64988445 and ends at 65023866 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
PSAT1 (9q21.2) / SLC1A4 (2p14)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC1A4   10942
Cards
Entrez_Gene (NCBI)SLC1A4  6509  solute carrier family 1 member 4
AliasesASCT1; SATT; SPATCCM
GeneCards (Weizmann)SLC1A4
Ensembl hg19 (Hinxton)ENSG00000115902 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000115902 [Gene_View]  chr2:64988445-65023866 [Contig_View]  SLC1A4 [Vega]
ICGC DataPortalENSG00000115902
TCGA cBioPortalSLC1A4
AceView (NCBI)SLC1A4
Genatlas (Paris)SLC1A4
WikiGenes6509
SOURCE (Princeton)SLC1A4
Genetics Home Reference (NIH)SLC1A4
Genomic and cartography
GoldenPath hg38 (UCSC)SLC1A4  -     chr2:64988445-65023866 +  2p14   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC1A4  -     2p14   [Description]    (hg19-Feb_2009)
EnsemblSLC1A4 - 2p14 [CytoView hg19]  SLC1A4 - 2p14 [CytoView hg38]
Mapping of homologs : NCBISLC1A4 [Mapview hg19]  SLC1A4 [Mapview hg38]
OMIM600229   616657   
Gene and transcription
Genbank (Entrez)AB026689 AK126636 AK223486 AK295687 AK298472
RefSeq transcript (Entrez)NM_001135581 NM_001193493 NM_001348406 NM_001348407 NM_003038
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC1A4
Cluster EST : UnigeneHs.654352 [ NCBI ]
CGAP (NCI)Hs.654352
Alternative Splicing GalleryENSG00000115902
Gene ExpressionSLC1A4 [ NCBI-GEO ]   SLC1A4 [ EBI - ARRAY_EXPRESS ]   SLC1A4 [ SEEK ]   SLC1A4 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC1A4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6509
GTEX Portal (Tissue expression)SLC1A4
Protein : pattern, domain, 3D structure
UniProt/SwissProtP43007   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP43007  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP43007
Splice isoforms : SwissVarP43007
PhosPhoSitePlusP43007
Domaine pattern : Prosite (Expaxy)NA_DICARBOXYL_SYMP_1 (PS00713)    NA_DICARBOXYL_SYMP_2 (PS00714)   
Domains : Interpro (EBI)Na-dicarboxylate_symporter    Na-dicarboxylate_symporter_CS   
Domain families : Pfam (Sanger)SDF (PF00375)   
Domain families : Pfam (NCBI)pfam00375   
Conserved Domain (NCBI)SLC1A4
DMDM Disease mutations6509
Blocks (Seattle)SLC1A4
SuperfamilyP43007
Human Protein AtlasENSG00000115902
Peptide AtlasP43007
HPRD02576
IPIIPI00015476   IPI00913845   IPI00922120   
Protein Interaction databases
DIP (DOE-UCLA)P43007
IntAct (EBI)P43007
FunCoupENSG00000115902
BioGRIDSLC1A4
STRING (EMBL)SLC1A4
ZODIACSLC1A4
Ontologies - Pathways
QuickGOP43007
Ontology : AmiGOchloride channel activity  intermediate filament  plasma membrane  integral component of plasma membrane  amino acid transport  glutamine transport  cell surface  amino acid transmembrane transporter activity  L-alanine transmembrane transporter activity  L-cystine transmembrane transporter activity  L-cystine transmembrane transporter activity  L-glutamine transmembrane transporter activity  L-proline transmembrane transporter activity  L-serine transmembrane transporter activity  L-threonine transmembrane transporter activity  symporter activity  L-alanine transport  L-cystine transport  L-cystine transport  proline transport  L-serine transport  threonine transport  membrane  integral component of membrane  dendrite  hydroxyproline transport  L-hydroxyproline transmembrane transporter activity  synaptic transmission, glutamatergic  proline transmembrane transport  melanosome  neuronal cell body  cognition  extracellular exosome  chloride transmembrane transport  
Ontology : EGO-EBIchloride channel activity  intermediate filament  plasma membrane  integral component of plasma membrane  amino acid transport  glutamine transport  cell surface  amino acid transmembrane transporter activity  L-alanine transmembrane transporter activity  L-cystine transmembrane transporter activity  L-cystine transmembrane transporter activity  L-glutamine transmembrane transporter activity  L-proline transmembrane transporter activity  L-serine transmembrane transporter activity  L-threonine transmembrane transporter activity  symporter activity  L-alanine transport  L-cystine transport  L-cystine transport  proline transport  L-serine transport  threonine transport  membrane  integral component of membrane  dendrite  hydroxyproline transport  L-hydroxyproline transmembrane transporter activity  synaptic transmission, glutamatergic  proline transmembrane transport  melanosome  neuronal cell body  cognition  extracellular exosome  chloride transmembrane transport  
NDEx NetworkSLC1A4
Atlas of Cancer Signalling NetworkSLC1A4
Wikipedia pathwaysSLC1A4
Orthology - Evolution
OrthoDB6509
GeneTree (enSembl)ENSG00000115902
Phylogenetic Trees/Animal Genes : TreeFamSLC1A4
HOVERGENP43007
HOGENOMP43007
Homologs : HomoloGeneSLC1A4
Homology/Alignments : Family Browser (UCSC)SLC1A4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC1A4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC1A4
dbVarSLC1A4
ClinVarSLC1A4
1000_GenomesSLC1A4 
Exome Variant ServerSLC1A4
ExAC (Exome Aggregation Consortium)SLC1A4 (select the gene name)
Genetic variants : HAPMAP6509
Genomic Variants (DGV)SLC1A4 [DGVbeta]
DECIPHERSLC1A4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC1A4 
Mutations
ICGC Data PortalSLC1A4 
TCGA Data PortalSLC1A4 
Broad Tumor PortalSLC1A4
OASIS PortalSLC1A4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC1A4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC1A4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC1A4
DgiDB (Drug Gene Interaction Database)SLC1A4
DoCM (Curated mutations)SLC1A4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC1A4 (select a term)
intoGenSLC1A4
Cancer3DSLC1A4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM600229    616657   
Orphanet23560   
MedgenSLC1A4
Genetic Testing Registry SLC1A4
NextProtP43007 [Medical]
TSGene6509
GENETestsSLC1A4
Target ValidationSLC1A4
Huge Navigator SLC1A4 [HugePedia]
snp3D : Map Gene to Disease6509
BioCentury BCIQSLC1A4
ClinGenSLC1A4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6509
Chemical/Pharm GKB GenePA35829
Clinical trialSLC1A4
Miscellaneous
canSAR (ICR)SLC1A4 (select the gene name)
Probes
Litterature
PubMed41 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC1A4
EVEXSLC1A4
GoPubMedSLC1A4
iHOPSLC1A4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Tue Aug 1 16:38:44 CEST 2017

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