Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SLC22A1 (solute carrier family 22 member 1)

Identity

Alias_namessolute carrier family 22 (organic cation transporter)
Alias_symbol (synonym)OCT1
Other aliasHOCT1
oct1_cds
HGNC (Hugo) SLC22A1
LocusID (NCBI) 6580
Atlas_Id 51461
Location 6q25.3  [Link to chromosome band 6q25]
Location_base_pair Starts at 160121831 and ends at 160158718 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SLC22A1 (6q25.3) / CUTA (6p21.32)SLC22A1 6q25.3 CUTA

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC22A1   10963
Cards
Entrez_Gene (NCBI)SLC22A1  6580  solute carrier family 22 member 1
AliasesHOCT1; OCT1; oct1_cds
GeneCards (Weizmann)SLC22A1
Ensembl hg19 (Hinxton)ENSG00000175003 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000175003 [Gene_View]  ENSG00000175003 [Sequence]  chr6:160121831-160158718 [Contig_View]  SLC22A1 [Vega]
ICGC DataPortalENSG00000175003
TCGA cBioPortalSLC22A1
AceView (NCBI)SLC22A1
Genatlas (Paris)SLC22A1
WikiGenes6580
SOURCE (Princeton)SLC22A1
Genetics Home Reference (NIH)SLC22A1
Genomic and cartography
GoldenPath hg38 (UCSC)SLC22A1  -     chr6:160121831-160158718 +  6q25.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC22A1  -     6q25.3   [Description]    (hg19-Feb_2009)
EnsemblSLC22A1 - 6q25.3 [CytoView hg19]  SLC22A1 - 6q25.3 [CytoView hg38]
Mapping of homologs : NCBISLC22A1 [Mapview hg19]  SLC22A1 [Mapview hg38]
OMIM602607   
Gene and transcription
Genbank (Entrez)AK289887 AV684761 BC126364 U77086 X98332
RefSeq transcript (Entrez)NM_003057 NM_153187
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC22A1
Cluster EST : UnigeneHs.117367 [ NCBI ]
CGAP (NCI)Hs.117367
Alternative Splicing GalleryENSG00000175003
Gene ExpressionSLC22A1 [ NCBI-GEO ]   SLC22A1 [ EBI - ARRAY_EXPRESS ]   SLC22A1 [ SEEK ]   SLC22A1 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC22A1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6580
GTEX Portal (Tissue expression)SLC22A1
Human Protein AtlasENSG00000175003-SLC22A1 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtO15245   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtO15245  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProO15245
Splice isoforms : SwissVarO15245
PhosPhoSitePlusO15245
Domaine pattern : Prosite (Expaxy)MFS (PS50850)    SUGAR_TRANSPORT_1 (PS00216)   
Domains : Interpro (EBI)MFS_dom    MFS_sugar_transport-like    Orgcat_transp/SVOP    Sugar_transporter_CS   
Domain families : Pfam (Sanger)Sugar_tr (PF00083)   
Domain families : Pfam (NCBI)pfam00083   
Conserved Domain (NCBI)SLC22A1
DMDM Disease mutations6580
Blocks (Seattle)SLC22A1
SuperfamilyO15245
Human Protein Atlas [tissue]ENSG00000175003-SLC22A1 [tissue]
Peptide AtlasO15245
HPRD04007
IPIIPI00289507   IPI00893977   IPI00893835   IPI00953438   IPI01010117   IPI01010628   
Protein Interaction databases
DIP (DOE-UCLA)O15245
IntAct (EBI)O15245
FunCoupENSG00000175003
BioGRIDSLC22A1
STRING (EMBL)SLC22A1
ZODIACSLC22A1
Ontologies - Pathways
QuickGOO15245
Ontology : AmiGOacetylcholine transmembrane transporter activity  dopamine transmembrane transporter activity  norepinephrine transmembrane transporter activity  protein binding  plasma membrane  integral component of plasma membrane  neurotransmitter transport  drug transmembrane transport  secondary active organic cation transmembrane transporter activity  organic anion transmembrane transporter activity  establishment or maintenance of transmembrane electrochemical gradient  organic cation transmembrane transporter activity  organic cation transmembrane transporter activity  quaternary ammonium group transmembrane transporter activity  organic cation transport  quaternary ammonium group transport  organic anion transport  dopamine transport  norepinephrine transport  membrane  basolateral plasma membrane  protein homodimerization activity  epinephrine transport  protein homooligomerization  ammonium transmembrane transport  acetate ester transport  
Ontology : EGO-EBIacetylcholine transmembrane transporter activity  dopamine transmembrane transporter activity  norepinephrine transmembrane transporter activity  protein binding  plasma membrane  integral component of plasma membrane  neurotransmitter transport  drug transmembrane transport  secondary active organic cation transmembrane transporter activity  organic anion transmembrane transporter activity  establishment or maintenance of transmembrane electrochemical gradient  organic cation transmembrane transporter activity  organic cation transmembrane transporter activity  quaternary ammonium group transmembrane transporter activity  organic cation transport  quaternary ammonium group transport  organic anion transport  dopamine transport  norepinephrine transport  membrane  basolateral plasma membrane  protein homodimerization activity  epinephrine transport  protein homooligomerization  ammonium transmembrane transport  acetate ester transport  
NDEx NetworkSLC22A1
Atlas of Cancer Signalling NetworkSLC22A1
Wikipedia pathwaysSLC22A1
Orthology - Evolution
OrthoDB6580
GeneTree (enSembl)ENSG00000175003
Phylogenetic Trees/Animal Genes : TreeFamSLC22A1
HOVERGENO15245
HOGENOMO15245
Homologs : HomoloGeneSLC22A1
Homology/Alignments : Family Browser (UCSC)SLC22A1
Gene fusions - Rearrangements
Fusion : QuiverSLC22A1
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC22A1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC22A1
dbVarSLC22A1
ClinVarSLC22A1
1000_GenomesSLC22A1 
Exome Variant ServerSLC22A1
ExAC (Exome Aggregation Consortium)ENSG00000175003
GNOMAD BrowserENSG00000175003
Genetic variants : HAPMAP6580
Genomic Variants (DGV)SLC22A1 [DGVbeta]
DECIPHERSLC22A1 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC22A1 
Mutations
ICGC Data PortalSLC22A1 
TCGA Data PortalSLC22A1 
Broad Tumor PortalSLC22A1
OASIS PortalSLC22A1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC22A1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC22A1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC22A1
DgiDB (Drug Gene Interaction Database)SLC22A1
DoCM (Curated mutations)SLC22A1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC22A1 (select a term)
intoGenSLC22A1
Cancer3DSLC22A1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM602607   
Orphanet
DisGeNETSLC22A1
MedgenSLC22A1
Genetic Testing Registry SLC22A1
NextProtO15245 [Medical]
TSGene6580
GENETestsSLC22A1
Target ValidationSLC22A1
Huge Navigator SLC22A1 [HugePedia]
snp3D : Map Gene to Disease6580
BioCentury BCIQSLC22A1
ClinGenSLC22A1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6580
Chemical/Pharm GKB GenePA329
Clinical trialSLC22A1
Miscellaneous
canSAR (ICR)SLC22A1 (select the gene name)
Probes
Litterature
PubMed128 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC22A1
EVEXSLC22A1
GoPubMedSLC22A1
iHOPSLC22A1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 22 16:49:57 CEST 2018

Home   Genes   Leukemias   Solid Tumors   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.