Atlas of Genetics and Cytogenetics in Oncology and Haematology

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SLC22A10 (solute carrier family 22 member 10)

Identity

Alias (NCBI)OAT5
hOAT5
HGNC (Hugo) SLC22A10
HGNC Alias symbOAT5
hOAT5
HGNC Previous namesolute carrier family 22 (organic anion/cation transporter), member 10
 solute carrier family 22, member 10
LocusID (NCBI) 387775
Atlas_Id 73314
Location 11q12.3  [Link to chromosome band 11q12]
Location_base_pair Starts at 63289958 and ends at 63311774 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
KMT2A (11q23.3) / SLC22A10 (11q12.3)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 1 ]
  t(11;11)(q12;q23) KMT2A/SLC22A10

External links

Nomenclature
HGNC (Hugo)SLC22A10   18057
Cards
Entrez_Gene (NCBI)SLC22A10    solute carrier family 22 member 10
AliasesOAT5; hOAT5
GeneCards (Weizmann)SLC22A10
Ensembl hg19 (Hinxton)ENSG00000184999 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000184999 [Gene_View]  ENSG00000184999 [Sequence]  chr11:63289958-63311774 [Contig_View]  SLC22A10 [Vega]
ICGC DataPortalENSG00000184999
TCGA cBioPortalSLC22A10
AceView (NCBI)SLC22A10
Genatlas (Paris)SLC22A10
SOURCE (Princeton)SLC22A10
Genetics Home Reference (NIH)SLC22A10
Genomic and cartography
GoldenPath hg38 (UCSC)SLC22A10  -     chr11:63289958-63311774 +  11q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC22A10  -     11q12.3   [Description]    (hg19-Feb_2009)
GoldenPathSLC22A10 - 11q12.3 [CytoView hg19]  SLC22A10 - 11q12.3 [CytoView hg38]
ImmunoBaseENSG00000184999
genome Data Viewer NCBISLC22A10 [Mapview hg19]  
OMIM607580   
Gene and transcription
Genbank (Entrez)AB075876 AK296299 AK298430 BC171744 BK001421
RefSeq transcript (Entrez)NM_001039752
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC22A10
Alternative Splicing GalleryENSG00000184999
Gene ExpressionSLC22A10 [ NCBI-GEO ]   SLC22A10 [ EBI - ARRAY_EXPRESS ]   SLC22A10 [ SEEK ]   SLC22A10 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC22A10 [ Firebrowse - Broad ]
GenevisibleExpression of SLC22A10 in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)387775
GTEX Portal (Tissue expression)SLC22A10
Human Protein AtlasENSG00000184999-SLC22A10 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ63ZE4   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ63ZE4  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ63ZE4
Splice isoforms : SwissVarQ63ZE4
PhosPhoSitePlusQ63ZE4
Domaine pattern : Prosite (Expaxy)MFS (PS50850)   
Domains : Interpro (EBI)MFS_dom    MFS_sugar_transport-like    MFS_trans_sf   
Domain families : Pfam (Sanger)Sugar_tr (PF00083)   
Domain families : Pfam (NCBI)pfam00083   
Conserved Domain (NCBI)SLC22A10
Blocks (Seattle)SLC22A10
SuperfamilyQ63ZE4
Human Protein Atlas [tissue]ENSG00000184999-SLC22A10 [tissue]
Peptide AtlasQ63ZE4
IPIIPI00470788   IPI00984058   IPI01009820   IPI00983645   IPI00984261   
Protein Interaction databases
DIP (DOE-UCLA)Q63ZE4
IntAct (EBI)Q63ZE4
BioGRIDSLC22A10
STRING (EMBL)SLC22A10
ZODIACSLC22A10
Ontologies - Pathways
QuickGOQ63ZE4
Ontology : AmiGOorganic anion transport  integral component of membrane  transmembrane transporter activity  transmembrane transport  
Ontology : EGO-EBIorganic anion transport  integral component of membrane  transmembrane transporter activity  transmembrane transport  
NDEx NetworkSLC22A10
Atlas of Cancer Signalling NetworkSLC22A10
Wikipedia pathwaysSLC22A10
Orthology - Evolution
OrthoDB387775
GeneTree (enSembl)ENSG00000184999
Phylogenetic Trees/Animal Genes : TreeFamSLC22A10
HOGENOMQ63ZE4
Homologs : HomoloGeneSLC22A10
Homology/Alignments : Family Browser (UCSC)SLC22A10
Gene fusions - Rearrangements
Fusion : QuiverSLC22A10
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC22A10 [hg38]
dbVarSLC22A10
ClinVarSLC22A10
MonarchSLC22A10
1000_GenomesSLC22A10 
Exome Variant ServerSLC22A10
GNOMAD BrowserENSG00000184999
Varsome BrowserSLC22A10
Genomic Variants (DGV)SLC22A10 [DGVbeta]
DECIPHERSLC22A10 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC22A10 
Mutations
ICGC Data PortalSLC22A10 
TCGA Data PortalSLC22A10 
Broad Tumor PortalSLC22A10
OASIS PortalSLC22A10 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC22A10  [overview]  [genome browser]  [tissue]  [distribution]  
Somatic Mutations in Cancer : COSMIC3DSLC22A10
Mutations and Diseases : HGMDSLC22A10
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC22A10
DgiDB (Drug Gene Interaction Database)SLC22A10
DoCM (Curated mutations)SLC22A10 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC22A10 (select a term)
intoGenSLC22A10
Cancer3DSLC22A10(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607580   
Orphanet
DisGeNETSLC22A10
MedgenSLC22A10
Genetic Testing Registry SLC22A10
NextProtQ63ZE4 [Medical]
GENETestsSLC22A10
Target ValidationSLC22A10
Huge Navigator SLC22A10 [HugePedia]
ClinGenSLC22A10
Clinical trials, drugs, therapy
MyCancerGenomeSLC22A10
Protein Interactions : CTD
Pharm GKB GenePA38283
Clinical trialSLC22A10
Miscellaneous
canSAR (ICR)SLC22A10 (select the gene name)
HarmonizomeSLC22A10
DataMed IndexSLC22A10
Probes
Litterature
PubMed6 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC22A10
EVEXSLC22A10
GoPubMedSLC22A10
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Sat Dec 5 17:26:57 CET 2020
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