Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC22A12 (solute carrier family 22 member 12)

Identity

Alias_namessolute carrier family 22 (organic anion/cation transporter), member 12
solute carrier family 22 (organic anion/urate transporter), member 12
Alias_symbol (synonym)OAT4L
RST
URAT1
Other alias
HGNC (Hugo) SLC22A12
LocusID (NCBI) 116085
Atlas_Id 73316
Location 11q13.1  [Link to chromosome band 11q13]
Location_base_pair Starts at 64590810 and ends at 64602353 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC22A12   17989
Cards
Entrez_Gene (NCBI)SLC22A12  116085  solute carrier family 22 member 12
AliasesOAT4L; RST; URAT1
GeneCards (Weizmann)SLC22A12
Ensembl hg19 (Hinxton)ENSG00000197891 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000197891 [Gene_View]  chr11:64590810-64602353 [Contig_View]  SLC22A12 [Vega]
ICGC DataPortalENSG00000197891
TCGA cBioPortalSLC22A12
AceView (NCBI)SLC22A12
Genatlas (Paris)SLC22A12
WikiGenes116085
SOURCE (Princeton)SLC22A12
Genetics Home Reference (NIH)SLC22A12
Genomic and cartography
GoldenPath hg38 (UCSC)SLC22A12  -     chr11:64590810-64602353 +  11q13.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC22A12  -     11q13.1   [Description]    (hg19-Feb_2009)
EnsemblSLC22A12 - 11q13.1 [CytoView hg19]  SLC22A12 - 11q13.1 [CytoView hg38]
Mapping of homologs : NCBISLC22A12 [Mapview hg19]  SLC22A12 [Mapview hg38]
OMIM220150   607096   
Gene and transcription
Genbank (Entrez)AB050269 AB071863 AK055737 AK122599 AK309588
RefSeq transcript (Entrez)NM_001276326 NM_001276327 NM_144585 NM_153378
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC22A12
Cluster EST : UnigeneHs.700182 [ NCBI ]
CGAP (NCI)Hs.700182
Alternative Splicing GalleryENSG00000197891
Gene ExpressionSLC22A12 [ NCBI-GEO ]   SLC22A12 [ EBI - ARRAY_EXPRESS ]   SLC22A12 [ SEEK ]   SLC22A12 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC22A12 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)116085
GTEX Portal (Tissue expression)SLC22A12
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ96S37   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ96S37  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ96S37
Splice isoforms : SwissVarQ96S37
PhosPhoSitePlusQ96S37
Domaine pattern : Prosite (Expaxy)MFS (PS50850)   
Domains : Interpro (EBI)MFS_dom    MFS_sugar_transport-like   
Domain families : Pfam (Sanger)Sugar_tr (PF00083)   
Domain families : Pfam (NCBI)pfam00083   
Conserved Domain (NCBI)SLC22A12
DMDM Disease mutations116085
Blocks (Seattle)SLC22A12
SuperfamilyQ96S37
Human Protein AtlasENSG00000197891
Peptide AtlasQ96S37
HPRD06160
IPIIPI00163325   IPI00432750   IPI00807688   IPI00744709   IPI00170660   
Protein Interaction databases
DIP (DOE-UCLA)Q96S37
IntAct (EBI)Q96S37
FunCoupENSG00000197891
BioGRIDSLC22A12
STRING (EMBL)SLC22A12
ZODIACSLC22A12
Ontologies - Pathways
QuickGOQ96S37
Ontology : AmiGOinorganic anion exchanger activity  plasma membrane  plasma membrane  integral component of plasma membrane  urate transmembrane transporter activity  urate transmembrane transporter activity  sodium-independent organic anion transmembrane transporter activity  inorganic anion transport  urate transport  integral component of membrane  apical plasma membrane  cellular homeostasis  PDZ domain binding  brush border membrane  brush border membrane  response to drug  sodium-independent organic anion transport  urate metabolic process  extracellular exosome  organic acid transmembrane transport  
Ontology : EGO-EBIinorganic anion exchanger activity  plasma membrane  plasma membrane  integral component of plasma membrane  urate transmembrane transporter activity  urate transmembrane transporter activity  sodium-independent organic anion transmembrane transporter activity  inorganic anion transport  urate transport  integral component of membrane  apical plasma membrane  cellular homeostasis  PDZ domain binding  brush border membrane  brush border membrane  response to drug  sodium-independent organic anion transport  urate metabolic process  extracellular exosome  organic acid transmembrane transport  
NDEx NetworkSLC22A12
Atlas of Cancer Signalling NetworkSLC22A12
Wikipedia pathwaysSLC22A12
Orthology - Evolution
OrthoDB116085
GeneTree (enSembl)ENSG00000197891
Phylogenetic Trees/Animal Genes : TreeFamSLC22A12
HOVERGENQ96S37
HOGENOMQ96S37
Homologs : HomoloGeneSLC22A12
Homology/Alignments : Family Browser (UCSC)SLC22A12
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC22A12 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC22A12
dbVarSLC22A12
ClinVarSLC22A12
1000_GenomesSLC22A12 
Exome Variant ServerSLC22A12
ExAC (Exome Aggregation Consortium)SLC22A12 (select the gene name)
Genetic variants : HAPMAP116085
Genomic Variants (DGV)SLC22A12 [DGVbeta]
DECIPHERSLC22A12 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC22A12 
Mutations
ICGC Data PortalSLC22A12 
TCGA Data PortalSLC22A12 
Broad Tumor PortalSLC22A12
OASIS PortalSLC22A12 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC22A12  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC22A12
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC22A12
DgiDB (Drug Gene Interaction Database)SLC22A12
DoCM (Curated mutations)SLC22A12 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC22A12 (select a term)
intoGenSLC22A12
Cancer3DSLC22A12(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM220150    607096   
Orphanet12557   
MedgenSLC22A12
Genetic Testing Registry SLC22A12
NextProtQ96S37 [Medical]
TSGene116085
GENETestsSLC22A12
Target ValidationSLC22A12
Huge Navigator SLC22A12 [HugePedia]
snp3D : Map Gene to Disease116085
BioCentury BCIQSLC22A12
ClinGenSLC22A12
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD116085
Chemical/Pharm GKB GenePA38478
Clinical trialSLC22A12
Miscellaneous
canSAR (ICR)SLC22A12 (select the gene name)
Probes
Litterature
PubMed80 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC22A12
EVEXSLC22A12
GoPubMedSLC22A12
iHOPSLC22A12
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 18 13:37:58 CEST 2017

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