Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC22A16 (solute carrier family 22 member 16)

Identity

Alias_namessolute carrier family 22 (organic cation transporter), member 16
solute carrier family 22 (organic cation/carnitine transporter), member 16
Alias_symbol (synonym)FLIPT2
CT2
OKB1
OAT6
Other aliasHEL-S-18
OCT6
dJ261K5.1
HGNC (Hugo) SLC22A16
LocusID (NCBI) 85413
Atlas_Id 46047
Location 6q21  [Link to chromosome band 6q21]
Location_base_pair Starts at 110424690 and ends at 110476641 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
METTL24 (6q21) / SLC22A16 (6q21)PRDM1 (6q21) / SLC22A16 (6q21)C6orf186 SLC22A16 6q21
PRDM1 6q21 / SLC22A16 6q21

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC22A16   20302
Cards
Entrez_Gene (NCBI)SLC22A16  85413  solute carrier family 22 member 16
AliasesCT2; FLIPT2; HEL-S-18; OAT6; 
OCT6; OKB1; dJ261K5.1
GeneCards (Weizmann)SLC22A16
Ensembl hg19 (Hinxton)ENSG00000004809 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000004809 [Gene_View]  ENSG00000004809 [Sequence]  chr6:110424690-110476641 [Contig_View]  SLC22A16 [Vega]
ICGC DataPortalENSG00000004809
TCGA cBioPortalSLC22A16
AceView (NCBI)SLC22A16
Genatlas (Paris)SLC22A16
WikiGenes85413
SOURCE (Princeton)SLC22A16
Genetics Home Reference (NIH)SLC22A16
Genomic and cartography
GoldenPath hg38 (UCSC)SLC22A16  -     chr6:110424690-110476641 -  6q21   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC22A16  -     6q21   [Description]    (hg19-Feb_2009)
EnsemblSLC22A16 - 6q21 [CytoView hg19]  SLC22A16 - 6q21 [CytoView hg38]
Mapping of homologs : NCBISLC22A16 [Mapview hg19]  SLC22A16 [Mapview hg38]
OMIM608276   
Gene and transcription
Genbank (Entrez)AB055798 AF268892 AI632467 AK057306 AK304546
RefSeq transcript (Entrez)NM_033125
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC22A16
Cluster EST : UnigeneHs.520319 [ NCBI ]
CGAP (NCI)Hs.520319
Alternative Splicing GalleryENSG00000004809
Gene ExpressionSLC22A16 [ NCBI-GEO ]   SLC22A16 [ EBI - ARRAY_EXPRESS ]   SLC22A16 [ SEEK ]   SLC22A16 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC22A16 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)85413
GTEX Portal (Tissue expression)SLC22A16
Human Protein AtlasENSG00000004809-SLC22A16 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ86VW1   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ86VW1  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ86VW1
Splice isoforms : SwissVarQ86VW1
PhosPhoSitePlusQ86VW1
Domaine pattern : Prosite (Expaxy)MFS (PS50850)   
Domains : Interpro (EBI)MFS_dom    MFS_sugar_transport-like   
Domain families : Pfam (Sanger)Sugar_tr (PF00083)   
Domain families : Pfam (NCBI)pfam00083   
Conserved Domain (NCBI)SLC22A16
DMDM Disease mutations85413
Blocks (Seattle)SLC22A16
SuperfamilyQ86VW1
Human Protein Atlas [tissue]ENSG00000004809-SLC22A16 [tissue]
Peptide AtlasQ86VW1
HPRD12202
IPIIPI00414651   IPI00335584   IPI00885182   IPI00909851   IPI00976673   IPI00642440   IPI00645863   
Protein Interaction databases
DIP (DOE-UCLA)Q86VW1
IntAct (EBI)Q86VW1
FunCoupENSG00000004809
BioGRIDSLC22A16
STRING (EMBL)SLC22A16
ZODIACSLC22A16
Ontologies - Pathways
QuickGOQ86VW1
Ontology : AmiGOamine transmembrane transporter activity  plasma membrane  plasma membrane  multicellular organism development  spermatogenesis  single fertilization  organic anion transmembrane transporter activity  organic cation transmembrane transporter activity  carnitine transmembrane transporter activity  carnitine transmembrane transporter activity  organic cation transport  organic anion transport  amine transport  carnitine transport  integral component of membrane  cell differentiation  flagellated sperm motility  acid secretion  carnitine transmembrane transport  
Ontology : EGO-EBIamine transmembrane transporter activity  plasma membrane  plasma membrane  multicellular organism development  spermatogenesis  single fertilization  organic anion transmembrane transporter activity  organic cation transmembrane transporter activity  carnitine transmembrane transporter activity  carnitine transmembrane transporter activity  organic cation transport  organic anion transport  amine transport  carnitine transport  integral component of membrane  cell differentiation  flagellated sperm motility  acid secretion  carnitine transmembrane transport  
NDEx NetworkSLC22A16
Atlas of Cancer Signalling NetworkSLC22A16
Wikipedia pathwaysSLC22A16
Orthology - Evolution
OrthoDB85413
GeneTree (enSembl)ENSG00000004809
Phylogenetic Trees/Animal Genes : TreeFamSLC22A16
HOVERGENQ86VW1
HOGENOMQ86VW1
Homologs : HomoloGeneSLC22A16
Homology/Alignments : Family Browser (UCSC)SLC22A16
Gene fusions - Rearrangements
Fusion PortalC6orf186 SLC22A16 6q21 LUAD
Fusion PortalPRDM1 6q21 SLC22A16 6q21 BRCA
Fusion : QuiverSLC22A16
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC22A16 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC22A16
dbVarSLC22A16
ClinVarSLC22A16
1000_GenomesSLC22A16 
Exome Variant ServerSLC22A16
ExAC (Exome Aggregation Consortium)ENSG00000004809
GNOMAD BrowserENSG00000004809
Genetic variants : HAPMAP85413
Genomic Variants (DGV)SLC22A16 [DGVbeta]
DECIPHERSLC22A16 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC22A16 
Mutations
ICGC Data PortalSLC22A16 
TCGA Data PortalSLC22A16 
Broad Tumor PortalSLC22A16
OASIS PortalSLC22A16 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC22A16  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC22A16
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC22A16
DgiDB (Drug Gene Interaction Database)SLC22A16
DoCM (Curated mutations)SLC22A16 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC22A16 (select a term)
intoGenSLC22A16
Cancer3DSLC22A16(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM608276   
Orphanet
DisGeNETSLC22A16
MedgenSLC22A16
Genetic Testing Registry SLC22A16
NextProtQ86VW1 [Medical]
TSGene85413
GENETestsSLC22A16
Target ValidationSLC22A16
Huge Navigator SLC22A16 [HugePedia]
snp3D : Map Gene to Disease85413
BioCentury BCIQSLC22A16
ClinGenSLC22A16
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD85413
Chemical/Pharm GKB GenePA134911502
Clinical trialSLC22A16
Miscellaneous
canSAR (ICR)SLC22A16 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC22A16
EVEXSLC22A16
GoPubMedSLC22A16
iHOPSLC22A16
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jun 22 16:49:57 CEST 2018

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