SLC22A17 (solute carrier family 22 member 17)

2009-03-01  

Identity

HGNC
LOCATION
14q11.2
LOCUSID
ALIAS
24p3R,BOCT,BOIT,NGALR,NGALR2,NGALR3,hBOIT
FUSION GENES

Other Information

Locus ID:

NCBI: 51310
MIM: 611461
HGNC: 23095
Ensembl: ENSG00000092096

Variants:

dbSNP: 51310
ClinVar: 51310
TCGA: ENSG00000092096
COSMIC: SLC22A17

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000092096ENST00000354772A0A1C7CYV9
ENSG00000092096ENST00000397260H9KVA1
ENSG00000092096ENST00000397267Q8WUG5
ENSG00000092096ENST00000474057H9KVA1
ENSG00000092096ENST00000474774A0A1B0GUC0
ENSG00000092096ENST00000636431A0A1B0GVR9

Expression (GTEx)

0
100
200
300
400
500
600

Pathways

PathwaySourceExternal ID
Transmembrane transport of small moleculesREACTOMER-HSA-382551
Iron uptake and transportREACTOMER-HSA-917937

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
262306412015Genetic variants in SLC22A17 and SLC22A7 are associated with anthracycline-induced cardiotoxicity in children.21
217633062011Immunohistochemical detection of a specific receptor for lipocalin2 (solute carrier family 22 member 17, SLC22A17) and its prognostic significance in endometrial carcinoma.14
227282792012NGAL and NGALR overexpression in human hepatocellular carcinoma toward a molecular prognostic classification.13
244524572014Lipocalin 2 decreases senescence of bone marrow-derived mesenchymal stem cells under sub-lethal doses of oxidative stress.12
266353662016Biochemical and Structural Characterization of the Interaction between the Siderocalin NGAL/LCN2 (Neutrophil Gelatinase-associated Lipocalin/Lipocalin 2) and the N-terminal Domain of Its Endocytic Receptor SLC22A17.10
190470932008NGALR is overexpressed and regulated by hypomethylation in esophageal squamous cell carcinoma.7
211841332011NGAL and NGALR are frequently overexpressed in human gliomas and are associated with clinical prognosis.7
213052512011Increased expression of neutrophil gelatinase-associated lipocalin receptor by interleukin-1β in human mesangial cells via MAPK/ERK activation.4
229321062012[Correlation of lipocalin-2 and its receptor expressions with preeclampsia].1
301386752018The expression analysis of NGAL and NGALR in clear cell renal cell carcinoma.1

Citation

Dessen P

SLC22A17 (solute carrier family 22 member 17)

Atlas Genet Cytogenet Oncol Haematol. 2009-03-01

Online version: http://atlasgeneticsoncology.org/gene/50715/slc22a17