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SLC22A23 (solute carrier family 22 member 23)

Identity

Alias_namesC6orf85
chromosome 6 open reading frame 85
solute carrier family 22, member 23
Alias_symbol (synonym)FLJ22174
Other alias
HGNC (Hugo) SLC22A23
LocusID (NCBI) 63027
Atlas_Id 54626
Location 6p25.2  [Link to chromosome band 6p25]
Location_base_pair Starts at 3268974 and ends at 3445013 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SLC22A23 (6p25.2) / CAMTA1 (1p36.31)SLC22A23 (6p25.2) / CDKAL1 (6p22.3)SLC22A23 (6p25.2) / ECHDC1 (6q22.33)
SLC22A23 (6p25.2) / GRIP1 (12q14.3)SLC22A23 (6p25.2) / NAALADL2 (3q26.31)SLC22A23 (6p25.2) / NRSN1 (6p22.3)
SLC22A23 (6p25.2) / SLC22A23 (6p25.2)SLC22A23 (6p25.2) / TNFRSF21 (6p12.3)SLC22A23 (6p25.2) / TRAF3 (14q32.32)
TUBB2A (6p25.2) / SLC22A23 (6p25.2)SLC22A23 6p25.2 / CAMTA1 1p36.31SLC22A23 6p25.2 / ECHDC1 6q22.33
SLC22A23 6p25.2 / GRIP1 12q14.3SLC22A23 6p25.2 / NAALADL2 3q26.31SLC22A23 6p25.2 / NRSN1 6p22.3
SLC22A23 6p25.2 / TNFRSF21 6p12.3SLC22A23 6p25.2 / TRAF3 14q32.32TUBB2A 6p25.2 / SLC22A23 6p25.2

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 8 ]
  t(1;6)(p36;p25) SLC22A23/CAMTA1
t(3;6)(q26;p25) SLC22A23/NAALADL2
t(6;6)(p12;p25) SLC22A23/TNFRSF21
t(6;6)(p22;p25) SLC22A23/NRSN1
TUBB2A/SLC22A23 (6p25)
t(6;6)(p25;q22) SLC22A23/ECHDC1
t(6;12)(p25;q14) SLC22A23/GRIP1
t(6;14)(p25;q32) SLC22A23/TRAF3


External links

Nomenclature
HGNC (Hugo)SLC22A23   21106
Cards
Entrez_Gene (NCBI)SLC22A23  63027  solute carrier family 22 member 23
AliasesC6orf85
GeneCards (Weizmann)SLC22A23
Ensembl hg19 (Hinxton)ENSG00000137266 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000137266 [Gene_View]  ENSG00000137266 [Sequence]  chr6:3268974-3445013 [Contig_View]  SLC22A23 [Vega]
ICGC DataPortalENSG00000137266
TCGA cBioPortalSLC22A23
AceView (NCBI)SLC22A23
Genatlas (Paris)SLC22A23
WikiGenes63027
SOURCE (Princeton)SLC22A23
Genetics Home Reference (NIH)SLC22A23
Genomic and cartography
GoldenPath hg38 (UCSC)SLC22A23  -     chr6:3268974-3445013 -  6p25.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC22A23  -     6p25.2   [Description]    (hg19-Feb_2009)
EnsemblSLC22A23 - 6p25.2 [CytoView hg19]  SLC22A23 - 6p25.2 [CytoView hg38]
Mapping of homologs : NCBISLC22A23 [Mapview hg19]  SLC22A23 [Mapview hg38]
OMIM611697   
Gene and transcription
Genbank (Entrez)AJ420525 AK000691 AK025033 AK025827 AK172770
RefSeq transcript (Entrez)NM_001286455 NM_001286456 NM_015482 NM_021945
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC22A23
Cluster EST : UnigeneHs.713588 [ NCBI ]
CGAP (NCI)Hs.713588
Alternative Splicing GalleryENSG00000137266
Gene ExpressionSLC22A23 [ NCBI-GEO ]   SLC22A23 [ EBI - ARRAY_EXPRESS ]   SLC22A23 [ SEEK ]   SLC22A23 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC22A23 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)63027
GTEX Portal (Tissue expression)SLC22A23
Human Protein AtlasENSG00000137266-SLC22A23 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtA1A5C7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtA1A5C7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProA1A5C7
Splice isoforms : SwissVarA1A5C7
PhosPhoSitePlusA1A5C7
Domaine pattern : Prosite (Expaxy)MFS (PS50850)    SUGAR_TRANSPORT_1 (PS00216)   
Domains : Interpro (EBI)MFS_dom    MFS_sugar_transport-like    MFS_trans_sf    Sugar_transporter_CS   
Domain families : Pfam (Sanger)Sugar_tr (PF00083)   
Domain families : Pfam (NCBI)pfam00083   
Conserved Domain (NCBI)SLC22A23
DMDM Disease mutations63027
Blocks (Seattle)SLC22A23
SuperfamilyA1A5C7
Human Protein Atlas [tissue]ENSG00000137266-SLC22A23 [tissue]
Peptide AtlasA1A5C7
HPRD12904
IPIIPI00868990   IPI00789245   IPI00868919   IPI00217176   IPI00030326   IPI00383850   IPI00945138   IPI00945478   IPI00945339   IPI00946531   
Protein Interaction databases
DIP (DOE-UCLA)A1A5C7
IntAct (EBI)A1A5C7
FunCoupENSG00000137266
BioGRIDSLC22A23
STRING (EMBL)SLC22A23
ZODIACSLC22A23
Ontologies - Pathways
QuickGOA1A5C7
Ontology : AmiGOprotein binding  ion transport  integral component of membrane  transmembrane transporter activity  transmembrane transport  
Ontology : EGO-EBIprotein binding  ion transport  integral component of membrane  transmembrane transporter activity  transmembrane transport  
NDEx NetworkSLC22A23
Atlas of Cancer Signalling NetworkSLC22A23
Wikipedia pathwaysSLC22A23
Orthology - Evolution
OrthoDB63027
GeneTree (enSembl)ENSG00000137266
Phylogenetic Trees/Animal Genes : TreeFamSLC22A23
HOVERGENA1A5C7
HOGENOMA1A5C7
Homologs : HomoloGeneSLC22A23
Homology/Alignments : Family Browser (UCSC)SLC22A23
Gene fusions - Rearrangements
Fusion : MitelmanSLC22A23/CAMTA1 [6p25.2/1p36.31]  
Fusion : MitelmanSLC22A23/ECHDC1 [6p25.2/6q22.33]  [t(6;6)(p25;q22)]  
Fusion : MitelmanSLC22A23/GRIP1 [6p25.2/12q14.3]  [t(6;12)(p25;q14)]  
Fusion : MitelmanSLC22A23/NAALADL2 [6p25.2/3q26.31]  [t(3;6)(q26;p25)]  
Fusion : MitelmanSLC22A23/NRSN1 [6p25.2/6p22.3]  [t(6;6)(p22;p25)]  
Fusion : MitelmanSLC22A23/TNFRSF21 [6p25.2/6p12.3]  [t(6;6)(p12;p25)]  
Fusion : MitelmanSLC22A23/TRAF3 [6p25.2/14q32.32]  [t(6;14)(p25;q32)]  
Fusion : MitelmanTUBB2A/SLC22A23 [6p25.2/6p25.2]  [t(6;6)(p25;p25)]  
Fusion PortalSLC22A23 6p25.2 CAMTA1 1p36.31 PRAD
Fusion PortalSLC22A23 6p25.2 ECHDC1 6q22.33 BLCA
Fusion PortalSLC22A23 6p25.2 GRIP1 12q14.3 BRCA
Fusion PortalSLC22A23 6p25.2 NAALADL2 3q26.31 BRCA
Fusion PortalSLC22A23 6p25.2 NRSN1 6p22.3 PRAD
Fusion PortalSLC22A23 6p25.2 TNFRSF21 6p12.3 GBM
Fusion PortalSLC22A23 6p25.2 TRAF3 14q32.32 LUSC
Fusion PortalTUBB2A 6p25.2 SLC22A23 6p25.2 LUAD
Fusion : QuiverSLC22A23
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC22A23 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC22A23
dbVarSLC22A23
ClinVarSLC22A23
1000_GenomesSLC22A23 
Exome Variant ServerSLC22A23
ExAC (Exome Aggregation Consortium)ENSG00000137266
GNOMAD BrowserENSG00000137266
Varsome BrowserSLC22A23
Genetic variants : HAPMAP63027
Genomic Variants (DGV)SLC22A23 [DGVbeta]
DECIPHERSLC22A23 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC22A23 
Mutations
ICGC Data PortalSLC22A23 
TCGA Data PortalSLC22A23 
Broad Tumor PortalSLC22A23
OASIS PortalSLC22A23 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC22A23  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC22A23
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC22A23
DgiDB (Drug Gene Interaction Database)SLC22A23
DoCM (Curated mutations)SLC22A23 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC22A23 (select a term)
intoGenSLC22A23
Cancer3DSLC22A23(select the gene name)
Impact of mutations[PolyPhen2] [Provean] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM611697   
Orphanet
DisGeNETSLC22A23
MedgenSLC22A23
Genetic Testing Registry SLC22A23
NextProtA1A5C7 [Medical]
TSGene63027
GENETestsSLC22A23
Target ValidationSLC22A23
Huge Navigator SLC22A23 [HugePedia]
snp3D : Map Gene to Disease63027
BioCentury BCIQSLC22A23
ClinGenSLC22A23
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD63027
Chemical/Pharm GKB GenePA162403516
Clinical trialSLC22A23
Miscellaneous
canSAR (ICR)SLC22A23 (select the gene name)
Probes
Litterature
PubMed21 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC22A23
EVEXSLC22A23
GoPubMedSLC22A23
iHOPSLC22A23
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 6 11:39:32 CET 2018

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