Atlas of Genetics and Cytogenetics in Oncology and Haematology


Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

X Y 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 NA

SLC22A4 (solute carrier family 22 (organic cation/zwitterion transporter), member 4)

Identity

Other namesOCTN1
HGNC (Hugo) SLC22A4
LocusID (NCBI) 6583
Location 5q31.1
Location_base_pair Starts at 131630145 and ends at 131679899 bp from pter ( according to hg19-Feb_2009)
Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

External links

Nomenclature
HGNC (Hugo)SLC22A4   10968
Cards
Entrez_Gene (NCBI)SLC22A4  6583  solute carrier family 22 (organic cation/zwitterion transporter), member 4
GeneCards (Weizmann)SLC22A4
Ensembl (Hinxton)ENSG00000197208 [Gene_View]  chr5:131630145-131679899 [Contig_View]  SLC22A4 [Vega]
ICGC DataPortalENSG00000197208
cBioPortalSLC22A4
AceView (NCBI)SLC22A4
Genatlas (Paris)SLC22A4
WikiGenes6583
SOURCE (Princeton)NM_003059
Genomic and cartography
GoldenPath (UCSC)SLC22A4  -  5q31.1   chr5:131630145-131679899 +  5q31.1   [Description]    (hg19-Feb_2009)
EnsemblSLC22A4 - 5q31.1 [CytoView]
Mapping of homologs : NCBISLC22A4 [Mapview]
OMIM180300   266600   604190   
Gene and transcription
Genbank (Entrez)AB007448 AK310818 BC028313 DQ890816 DQ893972
RefSeq transcript (Entrez)NM_003059
RefSeq genomic (Entrez)AC_000137 NC_000005 NC_018916 NG_012129 NT_034772 NW_001838952 NW_004929323
Consensus coding sequences : CCDS (NCBI)SLC22A4
Cluster EST : UnigeneHs.310591 [ NCBI ]
CGAP (NCI)Hs.310591
Alternative Splicing : Fast-db (Paris)GSHG0024221
Alternative Splicing GalleryENSG00000197208
Gene ExpressionSLC22A4 [ NCBI-GEO ]     SLC22A4 [ SEEK ]   SLC22A4 [ MEM ]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9H015 (Uniprot)
NextProtQ9H015  [Medical]
With graphics : InterProQ9H015
Splice isoforms : SwissVarQ9H015 (Swissvar)
Domaine pattern : Prosite (Expaxy)MFS (PS50850)    SUGAR_TRANSPORT_1 (PS00216)   
Domains : Interpro (EBI)MFS_dom [organisation]   MFS_dom_general_subst_transpt [organisation]   Orgcat_transp [organisation]   Sub_transporter [organisation]   Sugar_transporter_CS [organisation]  
Related proteins : CluSTrQ9H015
Domain families : Pfam (Sanger)Sugar_tr (PF00083)   
Domain families : Pfam (NCBI)pfam00083   
DMDM Disease mutations6583
Blocks (Seattle)Q9H015
Human Protein AtlasENSG00000197208 [gene] [tissue] [antibody] [cell] [cancer]
Peptide AtlasQ9H015
HPRD09171
IPIIPI00171334   IPI00892629   
Protein Interaction databases
DIP (DOE-UCLA)Q9H015
IntAct (EBI)Q9H015
FunCoupENSG00000197208
BioGRIDSLC22A4
InParanoidQ9H015
Interologous Interaction database Q9H015
IntegromeDBSLC22A4
STRING (EMBL)SLC22A4
Ontologies - Pathways
Ontology : AmiGOnucleotide binding  protein binding  ATP binding  mitochondrion  plasma membrane  plasma membrane  integral to plasma membrane  triglyceride metabolic process  sodium ion transport  body fluid secretion  secondary active organic cation transmembrane transporter activity  carnitine metabolic process  carnitine transmembrane transporter activity  symporter activity  cation:cation antiporter activity  quaternary ammonium group transmembrane transporter activity  organic cation transport  quaternary ammonium group transport  carnitine transport  apical plasma membrane  PDZ domain binding  transmembrane transport  
Ontology : EGO-EBInucleotide binding  protein binding  ATP binding  mitochondrion  plasma membrane  plasma membrane  integral to plasma membrane  triglyceride metabolic process  sodium ion transport  body fluid secretion  secondary active organic cation transmembrane transporter activity  carnitine metabolic process  carnitine transmembrane transporter activity  symporter activity  cation:cation antiporter activity  quaternary ammonium group transmembrane transporter activity  organic cation transport  quaternary ammonium group transport  carnitine transport  apical plasma membrane  PDZ domain binding  transmembrane transport  
Protein Interaction DatabaseSLC22A4
Wikipedia pathwaysSLC22A4
Gene fusion - rearrangments
Polymorphisms : SNP, mutations, diseases
SNP Single Nucleotide Polymorphism (NCBI)SLC22A4
snp3D : Map Gene to Disease6583
SNP (GeneSNP Utah)SLC22A4
SNP : HGBaseSLC22A4
Genetic variants : HAPMAPSLC22A4
Exome VariantSLC22A4
1000_GenomesSLC22A4 
ICGC programENSG00000197208 
Somatic Mutations in Cancer : COSMICSLC22A4 
CONAN: Copy Number AnalysisSLC22A4 
Mutations and Diseases : HGMDSLC22A4
Genomic VariantsSLC22A4  SLC22A4 [DGVbeta]
dbVarSLC22A4
ClinVarSLC22A4
Pred. of missensesPolyPhen-2  SIFT(SG)  SIFT(JCVI)  Align-GVGD  MutAssessor  Mutanalyser  
Pred. splicesGeneSplicer  Human Splicing Finder  MaxEntScan  
Diseases
OMIM180300    266600    604190   
MedgenSLC22A4
GENETestsSLC22A4
Disease Genetic AssociationSLC22A4
Huge Navigator SLC22A4 [HugePedia]  SLC22A4 [HugeCancerGEM]
General knowledge
Homologs : HomoloGeneSLC22A4
Homology/Alignments : Family Browser (UCSC)SLC22A4
Phylogenetic Trees/Animal Genes : TreeFamSLC22A4
Chemical/Protein Interactions : CTD6583
Chemical/Pharm GKB GenePA332
Clinical trialSLC22A4
Cancer Resource (Charite)ENSG00000197208
Other databases
Probes
Litterature
PubMed112 Pubmed reference(s) in Entrez
CoreMineSLC22A4
iHOPSLC22A4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

Search in all EBI   NCBI

Contributor(s)

Written09-2002Dessen P, Le Minor S
Updated12-2013Dessen P

© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Jul 11 17:19:18 CEST 2014

Home   Genes   Leukemias   Solid Tumours   Cancer-Prone   Deep Insight   Case Reports   Journals  Portal   Teaching   

For comments and suggestions or contributions, please contact us

jlhuret@AtlasGeneticsOncology.org.