Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC22A8 (solute carrier family 22 member 8)

Identity

Alias_namessolute carrier family 22 (organic anion transporter)
Alias_symbol (synonym)OAT3
Other alias
HGNC (Hugo) SLC22A8
LocusID (NCBI) 9376
Atlas_Id 55174
Location 11q12.3  [Link to chromosome band 11q12]
Location_base_pair Starts at 62992824 and ends at 63015845 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC22A8   10972
Cards
Entrez_Gene (NCBI)SLC22A8  9376  solute carrier family 22 member 8
AliasesOAT3
GeneCards (Weizmann)SLC22A8
Ensembl hg19 (Hinxton)ENSG00000149452 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000149452 [Gene_View]  chr11:62992824-63015845 [Contig_View]  SLC22A8 [Vega]
ICGC DataPortalENSG00000149452
TCGA cBioPortalSLC22A8
AceView (NCBI)SLC22A8
Genatlas (Paris)SLC22A8
WikiGenes9376
SOURCE (Princeton)SLC22A8
Genetics Home Reference (NIH)SLC22A8
Genomic and cartography
GoldenPath hg38 (UCSC)SLC22A8  -     chr11:62992824-63015845 -  11q12.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC22A8  -     11q12.3   [Description]    (hg19-Feb_2009)
EnsemblSLC22A8 - 11q12.3 [CytoView hg19]  SLC22A8 - 11q12.3 [CytoView hg38]
Mapping of homologs : NCBISLC22A8 [Mapview hg19]  SLC22A8 [Mapview hg38]
OMIM607581   
Gene and transcription
Genbank (Entrez)AB042505 AB209692 AF097491 AK123243 AK298341
RefSeq transcript (Entrez)NM_001184732 NM_001184733 NM_001184736 NM_004254
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC22A8
Cluster EST : UnigeneHs.266223 [ NCBI ]
CGAP (NCI)Hs.266223
Alternative Splicing GalleryENSG00000149452
Gene ExpressionSLC22A8 [ NCBI-GEO ]   SLC22A8 [ EBI - ARRAY_EXPRESS ]   SLC22A8 [ SEEK ]   SLC22A8 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC22A8 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)9376
GTEX Portal (Tissue expression)SLC22A8
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8TCC7   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8TCC7  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8TCC7
Splice isoforms : SwissVarQ8TCC7
PhosPhoSitePlusQ8TCC7
Domaine pattern : Prosite (Expaxy)MFS (PS50850)   
Domains : Interpro (EBI)MFS_dom    MFS_sugar_transport-like    Orgcat_transp/SVOP    Sugar_transporter_CS   
Domain families : Pfam (Sanger)Sugar_tr (PF00083)   
Domain families : Pfam (NCBI)pfam00083   
Conserved Domain (NCBI)SLC22A8
DMDM Disease mutations9376
Blocks (Seattle)SLC22A8
SuperfamilyQ8TCC7
Human Protein AtlasENSG00000149452
Peptide AtlasQ8TCC7
IPIIPI00163456   IPI00827526   IPI00827863   IPI00982691   IPI00975555   
Protein Interaction databases
DIP (DOE-UCLA)Q8TCC7
IntAct (EBI)Q8TCC7
FunCoupENSG00000149452
BioGRIDSLC22A8
STRING (EMBL)SLC22A8
ZODIACSLC22A8
Ontologies - Pathways
QuickGOQ8TCC7
Ontology : AmiGOinorganic anion exchanger activity  plasma membrane  integral component of plasma membrane  response to toxic substance  anion:anion antiporter activity  sodium-independent organic anion transmembrane transporter activity  inorganic anion transport  basolateral plasma membrane  sodium-independent organic anion transport  extracellular exosome  anion transmembrane transport  
Ontology : EGO-EBIinorganic anion exchanger activity  plasma membrane  integral component of plasma membrane  response to toxic substance  anion:anion antiporter activity  sodium-independent organic anion transmembrane transporter activity  inorganic anion transport  basolateral plasma membrane  sodium-independent organic anion transport  extracellular exosome  anion transmembrane transport  
Pathways : KEGGBile secretion   
NDEx NetworkSLC22A8
Atlas of Cancer Signalling NetworkSLC22A8
Wikipedia pathwaysSLC22A8
Orthology - Evolution
OrthoDB9376
GeneTree (enSembl)ENSG00000149452
Phylogenetic Trees/Animal Genes : TreeFamSLC22A8
HOVERGENQ8TCC7
HOGENOMQ8TCC7
Homologs : HomoloGeneSLC22A8
Homology/Alignments : Family Browser (UCSC)SLC22A8
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC22A8 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC22A8
dbVarSLC22A8
ClinVarSLC22A8
1000_GenomesSLC22A8 
Exome Variant ServerSLC22A8
ExAC (Exome Aggregation Consortium)SLC22A8 (select the gene name)
Genetic variants : HAPMAP9376
Genomic Variants (DGV)SLC22A8 [DGVbeta]
DECIPHERSLC22A8 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC22A8 
Mutations
ICGC Data PortalSLC22A8 
TCGA Data PortalSLC22A8 
Broad Tumor PortalSLC22A8
OASIS PortalSLC22A8 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC22A8  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC22A8
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC22A8
DgiDB (Drug Gene Interaction Database)SLC22A8
DoCM (Curated mutations)SLC22A8 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC22A8 (select a term)
intoGenSLC22A8
Cancer3DSLC22A8(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607581   
Orphanet
MedgenSLC22A8
Genetic Testing Registry SLC22A8
NextProtQ8TCC7 [Medical]
TSGene9376
GENETestsSLC22A8
Target ValidationSLC22A8
Huge Navigator SLC22A8 [HugePedia]
snp3D : Map Gene to Disease9376
BioCentury BCIQSLC22A8
ClinGenSLC22A8
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD9376
Chemical/Pharm GKB GenePA389
Clinical trialSLC22A8
Miscellaneous
canSAR (ICR)SLC22A8 (select the gene name)
Probes
Litterature
PubMed42 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC22A8
EVEXSLC22A8
GoPubMedSLC22A8
iHOPSLC22A8
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Mon Sep 25 19:31:23 CEST 2017

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