SLC23A2 (solute carrier family 23 member 2)

2008-10-01  

Identity

HGNC
LOCATION
20p13
LOCUSID
ALIAS
NBTL1,SLC23A1,SVCT2,YSPL2
FUSION GENES

Other Information

Locus ID:

NCBI: 9962
MIM: 603791
HGNC: 10973
Ensembl: ENSG00000089057

Variants:

dbSNP: 9962
ClinVar: 9962
TCGA: ENSG00000089057
COSMIC: SLC23A2

RNA/Proteins

Gene IDTranscript IDUniprot
ENSG00000089057ENST00000338244Q9UGH3
ENSG00000089057ENST00000338244A0A140VK48
ENSG00000089057ENST00000379333Q9UGH3
ENSG00000089057ENST00000379333A0A140VK48
ENSG00000089057ENST00000423430H0Y544

Expression (GTEx)

0
50
100
150

Pathways

PathwaySourceExternal ID
MetabolismREACTOMER-HSA-1430728
Metabolism of vitamins and cofactorsREACTOMER-HSA-196854
Metabolism of water-soluble vitamins and cofactorsREACTOMER-HSA-196849
Vitamin C (ascorbate) metabolismREACTOMER-HSA-196836

Protein levels (Protein atlas)

Not detected
Low
Medium
High

References

Pubmed IDYearTitleCitations
191621772009Vitamin C function in the brain: vital role of the ascorbate transporter SVCT2.133
203796142010Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.62
159938392005Polarized localization of vitamin C transporters, SVCT1 and SVCT2, in epithelial cells.36
186361242008Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma.32
186361242008Polymorphisms in the estrogen receptor 1 and vitamin C and matrix metalloproteinase gene families are associated with susceptibility to lymphoma.32
186766802008Pathway-based evaluation of 380 candidate genes and lung cancer susceptibility suggests the importance of the cell cycle pathway.32
196921682010Genetic susceptibility to distinct bladder cancer subphenotypes.25
163571102006Genetic variation in the sodium-dependent vitamin C transporters, SLC23A1, and SLC23A2 and risk for preterm delivery.24
163571102006Genetic variation in the sodium-dependent vitamin C transporters, SLC23A1, and SLC23A2 and risk for preterm delivery.24
204530002010A Large-scale genetic association study of esophageal adenocarcinoma risk.23

Citation

Dessen P

SLC23A2 (solute carrier family 23 member 2)

Atlas Genet Cytogenet Oncol Haematol. 2008-10-01

Online version: http://atlasgeneticsoncology.org/gene/50440/slc23a2