Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC24A2 (solute carrier family 24 member 2)

Identity

Alias_namessolute carrier family 24 (sodium/potassium/calcium exchanger), member 2
Alias_symbol (synonym)NCKX2
Other alias
HGNC (Hugo) SLC24A2
LocusID (NCBI) 25769
Atlas_Id 73329
Location 9p22.1  [Link to chromosome band 9p22]
Location_base_pair Starts at 19507452 and ends at 19787019 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
ADD1 (4p16.3) / SLC24A2 (9p22.1)GLUL (1q25.3) / SLC24A2 (9p22.1)SLC24A2 (9p22.1) / SPIDR (8q11.21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC24A2   10976
Cards
Entrez_Gene (NCBI)SLC24A2  25769  solute carrier family 24 member 2
AliasesNCKX2
GeneCards (Weizmann)SLC24A2
Ensembl hg19 (Hinxton)ENSG00000155886 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000155886 [Gene_View]  chr9:19507452-19787019 [Contig_View]  SLC24A2 [Vega]
ICGC DataPortalENSG00000155886
TCGA cBioPortalSLC24A2
AceView (NCBI)SLC24A2
Genatlas (Paris)SLC24A2
WikiGenes25769
SOURCE (Princeton)SLC24A2
Genetics Home Reference (NIH)SLC24A2
Genomic and cartography
GoldenPath hg38 (UCSC)SLC24A2  -     chr9:19507452-19787019 -  9p22.1   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC24A2  -     9p22.1   [Description]    (hg19-Feb_2009)
EnsemblSLC24A2 - 9p22.1 [CytoView hg19]  SLC24A2 - 9p22.1 [CytoView hg38]
Mapping of homologs : NCBISLC24A2 [Mapview hg19]  SLC24A2 [Mapview hg38]
OMIM609838   
Gene and transcription
Genbank (Entrez)AF097366 AF177987 AK127092 BC037528 BC069622
RefSeq transcript (Entrez)NM_001193288 NM_020344
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC24A2
Cluster EST : UnigeneHs.738749 [ NCBI ]
CGAP (NCI)Hs.738749
Alternative Splicing GalleryENSG00000155886
Gene ExpressionSLC24A2 [ NCBI-GEO ]   SLC24A2 [ EBI - ARRAY_EXPRESS ]   SLC24A2 [ SEEK ]   SLC24A2 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC24A2 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)25769
GTEX Portal (Tissue expression)SLC24A2
Human Protein AtlasENSG00000155886-SLC24A2 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UI40   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UI40  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UI40
Splice isoforms : SwissVarQ9UI40
PhosPhoSitePlusQ9UI40
Domains : Interpro (EBI)K/Na/Ca-exchanger    NaCa_Exmemb   
Domain families : Pfam (Sanger)Na_Ca_ex (PF01699)   
Domain families : Pfam (NCBI)pfam01699   
Conserved Domain (NCBI)SLC24A2
DMDM Disease mutations25769
Blocks (Seattle)SLC24A2
SuperfamilyQ9UI40
Human Protein Atlas [tissue]ENSG00000155886-SLC24A2 [tissue]
Peptide AtlasQ9UI40
HPRD15351
IPIIPI00006444   IPI00218809   
Protein Interaction databases
DIP (DOE-UCLA)Q9UI40
IntAct (EBI)Q9UI40
FunCoupENSG00000155886
BioGRIDSLC24A2
STRING (EMBL)SLC24A2
ZODIACSLC24A2
Ontologies - Pathways
QuickGOQ9UI40
Ontology : AmiGOcalcium channel activity  calcium ion binding  plasma membrane  integral component of plasma membrane  ion transport  potassium ion transport  cellular calcium ion homeostasis  visual perception  learning  memory  calcium, potassium:sodium antiporter activity  calcium, potassium:sodium antiporter activity  symporter activity  nickel cation binding  manganese ion binding  potassium ion binding  sodium ion binding  ion transmembrane transport  sodium ion transmembrane transport  cadmium ion binding  protein dimerization activity  response to stimulus  long-term synaptic potentiation  long term synaptic depression  calcium ion transmembrane transport  
Ontology : EGO-EBIcalcium channel activity  calcium ion binding  plasma membrane  integral component of plasma membrane  ion transport  potassium ion transport  cellular calcium ion homeostasis  visual perception  learning  memory  calcium, potassium:sodium antiporter activity  calcium, potassium:sodium antiporter activity  symporter activity  nickel cation binding  manganese ion binding  potassium ion binding  sodium ion binding  ion transmembrane transport  sodium ion transmembrane transport  cadmium ion binding  protein dimerization activity  response to stimulus  long-term synaptic potentiation  long term synaptic depression  calcium ion transmembrane transport  
NDEx NetworkSLC24A2
Atlas of Cancer Signalling NetworkSLC24A2
Wikipedia pathwaysSLC24A2
Orthology - Evolution
OrthoDB25769
GeneTree (enSembl)ENSG00000155886
Phylogenetic Trees/Animal Genes : TreeFamSLC24A2
HOVERGENQ9UI40
HOGENOMQ9UI40
Homologs : HomoloGeneSLC24A2
Homology/Alignments : Family Browser (UCSC)SLC24A2
Gene fusions - Rearrangements
Fusion: Tumor Portal SLC24A2
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC24A2 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC24A2
dbVarSLC24A2
ClinVarSLC24A2
1000_GenomesSLC24A2 
Exome Variant ServerSLC24A2
ExAC (Exome Aggregation Consortium)ENSG00000155886
GNOMAD BrowserENSG00000155886
Genetic variants : HAPMAP25769
Genomic Variants (DGV)SLC24A2 [DGVbeta]
DECIPHERSLC24A2 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC24A2 
Mutations
ICGC Data PortalSLC24A2 
TCGA Data PortalSLC24A2 
Broad Tumor PortalSLC24A2
OASIS PortalSLC24A2 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC24A2  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC24A2
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC24A2
DgiDB (Drug Gene Interaction Database)SLC24A2
DoCM (Curated mutations)SLC24A2 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC24A2 (select a term)
intoGenSLC24A2
Cancer3DSLC24A2(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609838   
Orphanet
MedgenSLC24A2
Genetic Testing Registry SLC24A2
NextProtQ9UI40 [Medical]
TSGene25769
GENETestsSLC24A2
Target ValidationSLC24A2
Huge Navigator SLC24A2 [HugePedia]
snp3D : Map Gene to Disease25769
BioCentury BCIQSLC24A2
ClinGenSLC24A2
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD25769
Chemical/Pharm GKB GenePA35852
Clinical trialSLC24A2
Miscellaneous
canSAR (ICR)SLC24A2 (select the gene name)
Probes
Litterature
PubMed27 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC24A2
EVEXSLC24A2
GoPubMedSLC24A2
iHOPSLC24A2
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Thu Nov 9 12:27:22 CET 2017

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