Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC24A3 (solute carrier family 24 member 3)

Identity

Alias_namessolute carrier family 24 (sodium/potassium/calcium exchanger), member 3
Other aliasNCKX3
HGNC (Hugo) SLC24A3
LocusID (NCBI) 57419
Atlas_Id 73330
Location 20p11.23  [Link to chromosome band 20p11]
Location_base_pair Starts at 19212646 and ends at 19722897 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2016)
SLC24A3 (20p11.23) / DDAH1 (1p22.3)SLC24A3 (20p11.23) / PLCB4 (20p12.2)SLX4IP (20p12.2) / SLC24A3 (20p11.23)
TASP1 (20p12.1) / SLC24A3 (20p11.23)C20orf94 SLC24A3TASP1 SLC24A3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC24A3   10977
Cards
Entrez_Gene (NCBI)SLC24A3  57419  solute carrier family 24 member 3
AliasesNCKX3
GeneCards (Weizmann)SLC24A3
Ensembl hg19 (Hinxton)ENSG00000185052 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000185052 [Gene_View]  chr20:19212646-19722897 [Contig_View]  SLC24A3 [Vega]
ICGC DataPortalENSG00000185052
TCGA cBioPortalSLC24A3
AceView (NCBI)SLC24A3
Genatlas (Paris)SLC24A3
WikiGenes57419
SOURCE (Princeton)SLC24A3
Genetics Home Reference (NIH)SLC24A3
Genomic and cartography
GoldenPath hg38 (UCSC)SLC24A3  -     chr20:19212646-19722897 +  20p11.23   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC24A3  -     20p11.23   [Description]    (hg19-Feb_2009)
EnsemblSLC24A3 - 20p11.23 [CytoView hg19]  SLC24A3 - 20p11.23 [CytoView hg38]
Mapping of homologs : NCBISLC24A3 [Mapview hg19]  SLC24A3 [Mapview hg38]
OMIM609839   
Gene and transcription
Genbank (Entrez)AF169257 AF288087 BC141432
RefSeq transcript (Entrez)NM_020689
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC24A3
Cluster EST : UnigeneHs.654790 [ NCBI ]
CGAP (NCI)Hs.654790
Alternative Splicing GalleryENSG00000185052
Gene ExpressionSLC24A3 [ NCBI-GEO ]   SLC24A3 [ EBI - ARRAY_EXPRESS ]   SLC24A3 [ SEEK ]   SLC24A3 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC24A3 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)57419
GTEX Portal (Tissue expression)SLC24A3
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9HC58   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9HC58  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9HC58
Splice isoforms : SwissVarQ9HC58
PhosPhoSitePlusQ9HC58
Domains : Interpro (EBI)K/Na/Ca-exchanger    NaCa_Exmemb    SLC24A3   
Domain families : Pfam (Sanger)Na_Ca_ex (PF01699)   
Domain families : Pfam (NCBI)pfam01699   
Conserved Domain (NCBI)SLC24A3
DMDM Disease mutations57419
Blocks (Seattle)SLC24A3
SuperfamilyQ9HC58
Human Protein AtlasENSG00000185052
Peptide AtlasQ9HC58
HPRD15352
IPIIPI00010272   
Protein Interaction databases
DIP (DOE-UCLA)Q9HC58
IntAct (EBI)Q9HC58
FunCoupENSG00000185052
BioGRIDSLC24A3
STRING (EMBL)SLC24A3
ZODIACSLC24A3
Ontologies - Pathways
QuickGOQ9HC58
Ontology : AmiGOcalcium channel activity  calcium ion binding  plasma membrane  integral component of plasma membrane  ion transport  potassium ion transport  cellular calcium ion homeostasis  calcium, potassium:sodium antiporter activity  calcium, potassium:sodium antiporter activity  symporter activity  potassium ion binding  sodium ion binding  sodium ion transmembrane transport  calcium ion transmembrane transport  
Ontology : EGO-EBIcalcium channel activity  calcium ion binding  plasma membrane  integral component of plasma membrane  ion transport  potassium ion transport  cellular calcium ion homeostasis  calcium, potassium:sodium antiporter activity  calcium, potassium:sodium antiporter activity  symporter activity  potassium ion binding  sodium ion binding  sodium ion transmembrane transport  calcium ion transmembrane transport  
NDEx NetworkSLC24A3
Atlas of Cancer Signalling NetworkSLC24A3
Wikipedia pathwaysSLC24A3
Orthology - Evolution
OrthoDB57419
GeneTree (enSembl)ENSG00000185052
Phylogenetic Trees/Animal Genes : TreeFamSLC24A3
HOVERGENQ9HC58
HOGENOMQ9HC58
Homologs : HomoloGeneSLC24A3
Homology/Alignments : Family Browser (UCSC)SLC24A3
Gene fusions - Rearrangements
Fusion: TCGAC20orf94 SLC24A3
Fusion: TCGATASP1 SLC24A3
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC24A3 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC24A3
dbVarSLC24A3
ClinVarSLC24A3
1000_GenomesSLC24A3 
Exome Variant ServerSLC24A3
ExAC (Exome Aggregation Consortium)SLC24A3 (select the gene name)
Genetic variants : HAPMAP57419
Genomic Variants (DGV)SLC24A3 [DGVbeta]
DECIPHERSLC24A3 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC24A3 
Mutations
ICGC Data PortalSLC24A3 
TCGA Data PortalSLC24A3 
Broad Tumor PortalSLC24A3
OASIS PortalSLC24A3 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC24A3  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC24A3
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC24A3
DgiDB (Drug Gene Interaction Database)SLC24A3
DoCM (Curated mutations)SLC24A3 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC24A3 (select a term)
intoGenSLC24A3
Cancer3DSLC24A3(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM609839   
Orphanet
MedgenSLC24A3
Genetic Testing Registry SLC24A3
NextProtQ9HC58 [Medical]
TSGene57419
GENETestsSLC24A3
Target ValidationSLC24A3
Huge Navigator SLC24A3 [HugePedia]
snp3D : Map Gene to Disease57419
BioCentury BCIQSLC24A3
ClinGenSLC24A3
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD57419
Chemical/Pharm GKB GenePA35853
Clinical trialSLC24A3
Miscellaneous
canSAR (ICR)SLC24A3 (select the gene name)
Probes
Litterature
PubMed8 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC24A3
EVEXSLC24A3
GoPubMedSLC24A3
iHOPSLC24A3
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 31 15:41:00 CEST 2017

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