Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC24A4 (solute carrier family 24 member 4)

Identity

Alias_namessolute carrier family 24 (sodium/potassium/calcium exchanger), member 4
Alias_symbol (synonym)NCKX4
Other aliasAI2A5
SHEP6
SLC24A2
HGNC (Hugo) SLC24A4
LocusID (NCBI) 123041
Atlas_Id 73331
Location 14q32.12  [Link to chromosome band 14q32]
Location_base_pair Starts at 92323808 and ends at 92501481 bp from pter ( according to hg38-Dec_2013)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC24A4   10978
Cards
Entrez_Gene (NCBI)SLC24A4  123041  solute carrier family 24 member 4
AliasesAI2A5; NCKX4; SHEP6; SLC24A2
GeneCards (Weizmann)SLC24A4
Ensembl hg19 (Hinxton)ENSG00000140090 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000140090 [Gene_View]  chr14:92323808-92501481 [Contig_View]  SLC24A4 [Vega]
ICGC DataPortalENSG00000140090
TCGA cBioPortalSLC24A4
AceView (NCBI)SLC24A4
Genatlas (Paris)SLC24A4
WikiGenes123041
SOURCE (Princeton)SLC24A4
Genetics Home Reference (NIH)SLC24A4
Genomic and cartography
GoldenPath hg38 (UCSC)SLC24A4  -     chr14:92323808-92501481 +  14q32.12   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC24A4  -     14q32.12   [Description]    (hg19-Feb_2009)
EnsemblSLC24A4 - 14q32.12 [CytoView hg19]  SLC24A4 - 14q32.12 [CytoView hg38]
Mapping of homologs : NCBISLC24A4 [Mapview hg19]  SLC24A4 [Mapview hg38]
OMIM210750   609840   615887   
Gene and transcription
Genbank (Entrez)AF520704 AF520705 AF520706 AK096171 AK295059
RefSeq transcript (Entrez)NM_153646 NM_153647 NM_153648
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC24A4
Cluster EST : UnigeneHs.385530 [ NCBI ]
CGAP (NCI)Hs.385530
Alternative Splicing GalleryENSG00000140090
Gene ExpressionSLC24A4 [ NCBI-GEO ]   SLC24A4 [ EBI - ARRAY_EXPRESS ]   SLC24A4 [ SEEK ]   SLC24A4 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC24A4 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)123041
GTEX Portal (Tissue expression)SLC24A4
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ8NFF2   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ8NFF2  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ8NFF2
Splice isoforms : SwissVarQ8NFF2
PhosPhoSitePlusQ8NFF2
Domains : Interpro (EBI)K/Na/Ca-exchanger    NaCa_Exmemb    SLC24A4   
Domain families : Pfam (Sanger)Na_Ca_ex (PF01699)   
Domain families : Pfam (NCBI)pfam01699   
Conserved Domain (NCBI)SLC24A4
DMDM Disease mutations123041
Blocks (Seattle)SLC24A4
SuperfamilyQ8NFF2
Human Protein AtlasENSG00000140090
Peptide AtlasQ8NFF2
HPRD15353
IPIIPI00982723   IPI00254233   IPI00254236   IPI00177492   IPI01022485   IPI01025340   IPI01023054   IPI00980833   
Protein Interaction databases
DIP (DOE-UCLA)Q8NFF2
IntAct (EBI)Q8NFF2
FunCoupENSG00000140090
BioGRIDSLC24A4
STRING (EMBL)SLC24A4
ZODIACSLC24A4
Ontologies - Pathways
QuickGOQ8NFF2
Ontology : AmiGOcalcium channel activity  calcium ion binding  cytoplasm  plasma membrane  integral component of plasma membrane  ion transport  potassium ion transport  cellular calcium ion homeostasis  sensory perception of smell  sensory perception of smell  calcium, potassium:sodium antiporter activity  calcium, potassium:sodium antiporter activity  symporter activity  membrane  potassium ion binding  sodium ion binding  sodium ion transmembrane transport  response to stimulus  calcium ion transmembrane transport  amelogenesis  
Ontology : EGO-EBIcalcium channel activity  calcium ion binding  cytoplasm  plasma membrane  integral component of plasma membrane  ion transport  potassium ion transport  cellular calcium ion homeostasis  sensory perception of smell  sensory perception of smell  calcium, potassium:sodium antiporter activity  calcium, potassium:sodium antiporter activity  symporter activity  membrane  potassium ion binding  sodium ion binding  sodium ion transmembrane transport  response to stimulus  calcium ion transmembrane transport  amelogenesis  
NDEx NetworkSLC24A4
Atlas of Cancer Signalling NetworkSLC24A4
Wikipedia pathwaysSLC24A4
Orthology - Evolution
OrthoDB123041
GeneTree (enSembl)ENSG00000140090
Phylogenetic Trees/Animal Genes : TreeFamSLC24A4
HOVERGENQ8NFF2
HOGENOMQ8NFF2
Homologs : HomoloGeneSLC24A4
Homology/Alignments : Family Browser (UCSC)SLC24A4
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC24A4 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC24A4
dbVarSLC24A4
ClinVarSLC24A4
1000_GenomesSLC24A4 
Exome Variant ServerSLC24A4
ExAC (Exome Aggregation Consortium)SLC24A4 (select the gene name)
Genetic variants : HAPMAP123041
Genomic Variants (DGV)SLC24A4 [DGVbeta]
DECIPHERSLC24A4 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC24A4 
Mutations
ICGC Data PortalSLC24A4 
TCGA Data PortalSLC24A4 
Broad Tumor PortalSLC24A4
OASIS PortalSLC24A4 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC24A4  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC24A4
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
BioMutasearch SLC24A4
DgiDB (Drug Gene Interaction Database)SLC24A4
DoCM (Curated mutations)SLC24A4 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC24A4 (select a term)
intoGenSLC24A4
Cancer3DSLC24A4(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM210750    609840    615887   
Orphanet14605    14606   
MedgenSLC24A4
Genetic Testing Registry SLC24A4
NextProtQ8NFF2 [Medical]
TSGene123041
GENETestsSLC24A4
Target ValidationSLC24A4
Huge Navigator SLC24A4 [HugePedia]
snp3D : Map Gene to Disease123041
BioCentury BCIQSLC24A4
ClinGenSLC24A4
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD123041
Chemical/Pharm GKB GenePA35854
Clinical trialSLC24A4
Miscellaneous
canSAR (ICR)SLC24A4 (select the gene name)
Probes
Litterature
PubMed20 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC24A4
EVEXSLC24A4
GoPubMedSLC24A4
iHOPSLC24A4
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Wed May 31 15:41:01 CEST 2017

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