Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC25A1 (solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1)

Identity

Alias_namesSLC20A3
solute carrier family 20 (mitochondrial citrate transporter), member 3
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
Alias_symbol (synonym)CTP
Other aliasD2L2AD
SEA
HGNC (Hugo) SLC25A1
LocusID (NCBI) 6576
Atlas_Id 73333
Location 22q11.21  [Link to chromosome band 22q11]
Location_base_pair Starts at 19163088 and ends at 19166018 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CBL (11q23.3) / SLC25A1 (22q11.21)JUN (1p32.1) / SLC25A1 (22q11.21)PLXNB1 (3p21.31) / SLC25A1 (22q11.21)
SLC25A1 (22q11.21) / FMNL3 (12q13.12)SLC25A1 (22q11.21) / HSPA13 (21q11.2)SLC25A1 (22q11.21) / JUN (1p32.1)
SLC25A1 (22q11.21) / MCL1 (1q21.3)SLC25A1 (22q11.21) / SLC25A1 (22q11.21)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC25A1   10979
Cards
Entrez_Gene (NCBI)SLC25A1  6576  solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
AliasesCTP; D2L2AD; SEA; SLC20A3
GeneCards (Weizmann)SLC25A1
Ensembl hg19 (Hinxton)ENSG00000100075 [Gene_View]  chr22:19163088-19166018 [Contig_View]  SLC25A1 [Vega]
Ensembl hg38 (Hinxton)ENSG00000100075 [Gene_View]  chr22:19163088-19166018 [Contig_View]  SLC25A1 [Vega]
ICGC DataPortalENSG00000100075
TCGA cBioPortalSLC25A1
AceView (NCBI)SLC25A1
Genatlas (Paris)SLC25A1
WikiGenes6576
SOURCE (Princeton)SLC25A1
Genetics Home Reference (NIH)SLC25A1
Genomic and cartography
GoldenPath hg19 (UCSC)SLC25A1  -     chr22:19163088-19166018 -  22q11.21   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SLC25A1  -     22q11.21   [Description]    (hg38-Dec_2013)
EnsemblSLC25A1 - 22q11.21 [CytoView hg19]  SLC25A1 - 22q11.21 [CytoView hg38]
Mapping of homologs : NCBISLC25A1 [Mapview hg19]  SLC25A1 [Mapview hg38]
OMIM190315   615182   
Gene and transcription
Genbank (Entrez)AK292313 AK298204 AW161974 AW249250 BC004980
RefSeq transcript (Entrez)NM_001256534 NM_001287387 NM_005984
RefSeq genomic (Entrez)NC_000022 NC_018933 NG_033863 NT_011520 NW_004929429
Consensus coding sequences : CCDS (NCBI)SLC25A1
Cluster EST : UnigeneHs.111024 [ NCBI ]
CGAP (NCI)Hs.111024
Alternative Splicing GalleryENSG00000100075
Gene ExpressionSLC25A1 [ NCBI-GEO ]   SLC25A1 [ EBI - ARRAY_EXPRESS ]   SLC25A1 [ SEEK ]   SLC25A1 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC25A1 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)6576
GTEX Portal (Tissue expression)SLC25A1
Protein : pattern, domain, 3D structure
UniProt/SwissProtP53007   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtP53007  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProP53007
Splice isoforms : SwissVarP53007
PhosPhoSitePlusP53007
Domaine pattern : Prosite (Expaxy)SOLCAR (PS50920)   
Domains : Interpro (EBI)Mit_carrier    Mitochondrial_sb/sol_carrier    Mt_carrier_dom   
Domain families : Pfam (Sanger)Mito_carr (PF00153)   
Domain families : Pfam (NCBI)pfam00153   
Conserved Domain (NCBI)SLC25A1
DMDM Disease mutations6576
Blocks (Seattle)SLC25A1
SuperfamilyP53007
Human Protein AtlasENSG00000100075
Peptide AtlasP53007
HPRD01832
IPIIPI00294159   IPI00852927   
Protein Interaction databases
DIP (DOE-UCLA)P53007
IntAct (EBI)P53007
FunCoupENSG00000100075
BioGRIDSLC25A1
STRING (EMBL)SLC25A1
ZODIACSLC25A1
Ontologies - Pathways
QuickGOP53007
Ontology : AmiGOnucleus  mitochondrial inner membrane  carbohydrate metabolic process  glucose metabolic process  gluconeogenesis  citrate transmembrane transporter activity  citrate transport  integral component of membrane  triglyceride biosynthetic process  long-chain fatty-acyl-CoA biosynthetic process  cellular lipid metabolic process  small molecule metabolic process  transmembrane transport  extracellular exosome  
Ontology : EGO-EBInucleus  mitochondrial inner membrane  carbohydrate metabolic process  glucose metabolic process  gluconeogenesis  citrate transmembrane transporter activity  citrate transport  integral component of membrane  triglyceride biosynthetic process  long-chain fatty-acyl-CoA biosynthetic process  cellular lipid metabolic process  small molecule metabolic process  transmembrane transport  extracellular exosome  
Pathways : BIOCARTAShuttle for transfer of acetyl groups from mitochondria to the cytosol [Genes]   
NDEx NetworkSLC25A1
Atlas of Cancer Signalling NetworkSLC25A1
Wikipedia pathwaysSLC25A1
Orthology - Evolution
OrthoDB6576
GeneTree (enSembl)ENSG00000100075
Phylogenetic Trees/Animal Genes : TreeFamSLC25A1
HOVERGENP53007
HOGENOMP53007
Homologs : HomoloGeneSLC25A1
Homology/Alignments : Family Browser (UCSC)SLC25A1
Gene fusions - Rearrangements
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC25A1 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC25A1
dbVarSLC25A1
ClinVarSLC25A1
1000_GenomesSLC25A1 
Exome Variant ServerSLC25A1
ExAC (Exome Aggregation Consortium)SLC25A1 (select the gene name)
Genetic variants : HAPMAP6576
Genomic Variants (DGV)SLC25A1 [DGVbeta]
DECIPHER (Syndromes)22:19163088-19166018  ENSG00000100075
CONAN: Copy Number AnalysisSLC25A1 
Mutations
ICGC Data PortalSLC25A1 
TCGA Data PortalSLC25A1 
Broad Tumor PortalSLC25A1
OASIS PortalSLC25A1 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC25A1  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC25A1
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch SLC25A1
DgiDB (Drug Gene Interaction Database)SLC25A1
DoCM (Curated mutations)SLC25A1 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC25A1 (select a term)
intoGenSLC25A1
Cancer3DSLC25A1(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM190315    615182   
Orphanet22190    13931   
MedgenSLC25A1
Genetic Testing Registry SLC25A1
NextProtP53007 [Medical]
TSGene6576
GENETestsSLC25A1
Huge Navigator SLC25A1 [HugePedia]
snp3D : Map Gene to Disease6576
BioCentury BCIQSLC25A1
ClinGenSLC25A1
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD6576
Chemical/Pharm GKB GenePA35855
Clinical trialSLC25A1
Miscellaneous
canSAR (ICR)SLC25A1 (select the gene name)
Probes
Litterature
PubMed52 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC25A1
EVEXSLC25A1
GoPubMedSLC25A1
iHOPSLC25A1
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Mar 14 12:43:27 CET 2017

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