Atlas of Genetics and Cytogenetics in Oncology and Haematology


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SLC25A11 (solute carrier family 25 member 11)

Identity

Alias_namesSLC20A4
solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
Alias_symbol (synonym)OGC
Other alias
HGNC (Hugo) SLC25A11
LocusID (NCBI) 8402
Atlas_Id 73335
Location 17p13.2  [Link to chromosome band 17p13]
Location_base_pair Starts at 4937131 and ends at 4940167 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)
Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
SLC25A11 (17p13.2) / KLHL3 (5q31.2)

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC25A11   10981
Cards
Entrez_Gene (NCBI)SLC25A11  8402  solute carrier family 25 member 11
AliasesOGC; SLC20A4
GeneCards (Weizmann)SLC25A11
Ensembl hg19 (Hinxton)ENSG00000108528 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000108528 [Gene_View]  chr17:4937131-4940167 [Contig_View]  SLC25A11 [Vega]
ICGC DataPortalENSG00000108528
TCGA cBioPortalSLC25A11
AceView (NCBI)SLC25A11
Genatlas (Paris)SLC25A11
WikiGenes8402
SOURCE (Princeton)SLC25A11
Genetics Home Reference (NIH)SLC25A11
Genomic and cartography
GoldenPath hg38 (UCSC)SLC25A11  -     chr17:4937131-4940167 -  17p13.2   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC25A11  -     17p13.2   [Description]    (hg19-Feb_2009)
EnsemblSLC25A11 - 17p13.2 [CytoView hg19]  SLC25A11 - 17p13.2 [CytoView hg38]
Mapping of homologs : NCBISLC25A11 [Mapview hg19]  SLC25A11 [Mapview hg38]
OMIM604165   
Gene and transcription
Genbank (Entrez)AA937945 AF070548 AK290376 AK313010 BC006508
RefSeq transcript (Entrez)NM_001165417 NM_001165418 NM_003562
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC25A11
Cluster EST : UnigeneHs.184877 [ NCBI ]
CGAP (NCI)Hs.184877
Alternative Splicing GalleryENSG00000108528
Gene ExpressionSLC25A11 [ NCBI-GEO ]   SLC25A11 [ EBI - ARRAY_EXPRESS ]   SLC25A11 [ SEEK ]   SLC25A11 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC25A11 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)8402
GTEX Portal (Tissue expression)SLC25A11
Human Protein AtlasENSG00000108528-SLC25A11 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ02978   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ02978  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ02978
Splice isoforms : SwissVarQ02978
PhosPhoSitePlusQ02978
Domaine pattern : Prosite (Expaxy)SOLCAR (PS50920)   
Domains : Interpro (EBI)Mitochondrial_sb/sol_carrier    Mt_carrier_dom   
Domain families : Pfam (Sanger)Mito_carr (PF00153)   
Domain families : Pfam (NCBI)pfam00153   
Conserved Domain (NCBI)SLC25A11
DMDM Disease mutations8402
Blocks (Seattle)SLC25A11
SuperfamilyQ02978
Human Protein Atlas [tissue]ENSG00000108528-SLC25A11 [tissue]
Peptide AtlasQ02978
HPRD05003
IPIIPI00219729   IPI00945233   IPI00797802   
Protein Interaction databases
DIP (DOE-UCLA)Q02978
IntAct (EBI)Q02978
FunCoupENSG00000108528
BioGRIDSLC25A11
STRING (EMBL)SLC25A11
ZODIACSLC25A11
Ontologies - Pathways
QuickGOQ02978
Ontology : AmiGORNA binding  nucleus  mitochondrion  mitochondrial inner membrane  mitochondrial inner membrane  integral component of plasma membrane  glucose metabolic process  gluconeogenesis  transport  mitochondrial transport  oxoglutarate:malate antiporter activity  oxoglutarate:malate antiporter activity  alpha-ketoglutarate transport  
Ontology : EGO-EBIRNA binding  nucleus  mitochondrion  mitochondrial inner membrane  mitochondrial inner membrane  integral component of plasma membrane  glucose metabolic process  gluconeogenesis  transport  mitochondrial transport  oxoglutarate:malate antiporter activity  oxoglutarate:malate antiporter activity  alpha-ketoglutarate transport  
Pathways : BIOCARTAShuttle for transfer of acetyl groups from mitochondria to the cytosol [Genes]    Malate-aspartate shuttle [Genes]   
NDEx NetworkSLC25A11
Atlas of Cancer Signalling NetworkSLC25A11
Wikipedia pathwaysSLC25A11
Orthology - Evolution
OrthoDB8402
GeneTree (enSembl)ENSG00000108528
Phylogenetic Trees/Animal Genes : TreeFamSLC25A11
HOVERGENQ02978
HOGENOMQ02978
Homologs : HomoloGeneSLC25A11
Homology/Alignments : Family Browser (UCSC)SLC25A11
Gene fusions - Rearrangements
Tumor Fusion PortalSLC25A11
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC25A11 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC25A11
dbVarSLC25A11
ClinVarSLC25A11
1000_GenomesSLC25A11 
Exome Variant ServerSLC25A11
ExAC (Exome Aggregation Consortium)ENSG00000108528
GNOMAD BrowserENSG00000108528
Genetic variants : HAPMAP8402
Genomic Variants (DGV)SLC25A11 [DGVbeta]
DECIPHERSLC25A11 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC25A11 
Mutations
ICGC Data PortalSLC25A11 
TCGA Data PortalSLC25A11 
Broad Tumor PortalSLC25A11
OASIS PortalSLC25A11 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC25A11  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC25A11
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch SLC25A11
DgiDB (Drug Gene Interaction Database)SLC25A11
DoCM (Curated mutations)SLC25A11 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC25A11 (select a term)
intoGenSLC25A11
Cancer3DSLC25A11(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM604165   
Orphanet
DisGeNETSLC25A11
MedgenSLC25A11
Genetic Testing Registry SLC25A11
NextProtQ02978 [Medical]
TSGene8402
GENETestsSLC25A11
Target ValidationSLC25A11
Huge Navigator SLC25A11 [HugePedia]
snp3D : Map Gene to Disease8402
BioCentury BCIQSLC25A11
ClinGenSLC25A11
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD8402
Chemical/Pharm GKB GenePA35857
Clinical trialSLC25A11
Miscellaneous
canSAR (ICR)SLC25A11 (select the gene name)
Probes
Litterature
PubMed51 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC25A11
EVEXSLC25A11
GoPubMedSLC25A11
iHOPSLC25A11
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Tue Nov 21 13:36:48 CET 2017

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