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SLC25A13 (solute carrier family 25 member 13)

Identity

Alias_namesCTLN2
solute carrier family 25, member 13 (citrin)
solute carrier family 25 (aspartate/glutamate carrier), member 13
Alias_symbol (synonym)CITRIN
ARALAR2
HGNC (Hugo) SLC25A13
LocusID (NCBI) 10165
Atlas_Id 52240
Location 7q21.3  [Link to chromosome band 7q21]
Location_base_pair Starts at 95749532 and ends at 95951459 bp from pter ( according to hg19-Feb_2009)
Fusion genes
(updated 2016)
CDK6 (7q21.2) / SLC25A13 (7q21.3)EXOC4 (7q33) / SLC25A13 (7q21.3)SLC25A13 (7q21.3) / SHFM1 (7q21.3)
SLC25A13 (7q21.3) / SLC25A13 (7q21.3)SLC25A13 (7q21.3) / STK31 (7p15.3)ZNF736 (7q11.21) / SLC25A13 (7q21.3)
EXOC4 7q33 / SLC25A13 7q21.3SLC25A13 7q21.3 / STK31 7p15.3

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 


External links

Nomenclature
HGNC (Hugo)SLC25A13   10983
Cards
Entrez_Gene (NCBI)SLC25A13  10165  solute carrier family 25 member 13
AliasesARALAR2; CITRIN; CTLN2
GeneCards (Weizmann)SLC25A13
Ensembl hg19 (Hinxton)ENSG00000004864 [Gene_View]  chr7:95749532-95951459 [Contig_View]  SLC25A13 [Vega]
Ensembl hg38 (Hinxton)ENSG00000004864 [Gene_View]  chr7:95749532-95951459 [Contig_View]  SLC25A13 [Vega]
ICGC DataPortalENSG00000004864
TCGA cBioPortalSLC25A13
AceView (NCBI)SLC25A13
Genatlas (Paris)SLC25A13
WikiGenes10165
SOURCE (Princeton)SLC25A13
Genetics Home Reference (NIH)SLC25A13
Genomic and cartography
GoldenPath hg19 (UCSC)SLC25A13  -     chr7:95749532-95951459 -  7q21.3   [Description]    (hg19-Feb_2009)
GoldenPath hg38 (UCSC)SLC25A13  -     7q21.3   [Description]    (hg38-Dec_2013)
EnsemblSLC25A13 - 7q21.3 [CytoView hg19]  SLC25A13 - 7q21.3 [CytoView hg38]
Mapping of homologs : NCBISLC25A13 [Mapview hg19]  SLC25A13 [Mapview hg38]
OMIM603471   603859   605814   
Gene and transcription
Genbank (Entrez)AF118838 AJ496569 AK000766 AK025227 AK025779
RefSeq transcript (Entrez)NM_001160210 NM_014251
RefSeq genomic (Entrez)NC_000007 NC_018918 NG_012247 NT_007933 NW_004929332
Consensus coding sequences : CCDS (NCBI)SLC25A13
Cluster EST : UnigeneHs.489190 [ NCBI ]
CGAP (NCI)Hs.489190
Alternative Splicing GalleryENSG00000004864
Gene ExpressionSLC25A13 [ NCBI-GEO ]   SLC25A13 [ EBI - ARRAY_EXPRESS ]   SLC25A13 [ SEEK ]   SLC25A13 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC25A13 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevisibleExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)10165
GTEX Portal (Tissue expression)SLC25A13
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9UJS0   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9UJS0  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9UJS0
Splice isoforms : SwissVarQ9UJS0
PhosPhoSitePlusQ9UJS0
Domaine pattern : Prosite (Expaxy)EF_HAND_2 (PS50222)    SOLCAR (PS50920)   
Domains : Interpro (EBI)Aralar2    EF-hand-dom_pair    EF_hand_dom    Mit_carrier    Mitochondrial_sb/sol_carrier    Mt_carrier_dom   
Domain families : Pfam (Sanger)Mito_carr (PF00153)   
Domain families : Pfam (NCBI)pfam00153   
Domain families : Smart (EMBL)EFh (SM00054)  
Conserved Domain (NCBI)SLC25A13
DMDM Disease mutations10165
Blocks (Seattle)SLC25A13
PDB (SRS)4P5W   
PDB (PDBSum)4P5W   
PDB (IMB)4P5W   
PDB (RSDB)4P5W   
Structural Biology KnowledgeBase4P5W   
SCOP (Structural Classification of Proteins)4P5W   
CATH (Classification of proteins structures)4P5W   
SuperfamilyQ9UJS0
Human Protein AtlasENSG00000004864
Peptide AtlasQ9UJS0
HPRD04837
IPIIPI00007084   IPI01012502   IPI00930710   
Protein Interaction databases
DIP (DOE-UCLA)Q9UJS0
IntAct (EBI)Q9UJS0
FunCoupENSG00000004864
BioGRIDSLC25A13
STRING (EMBL)SLC25A13
ZODIACSLC25A13
Ontologies - Pathways
QuickGOQ9UJS0
Ontology : AmiGOstructural constituent of ribosome  transporter activity  L-glutamate transmembrane transporter activity  calcium ion binding  mitochondrion  mitochondrial inner membrane  mitochondrial inner membrane  integral component of plasma membrane  gluconeogenesis  translation  ATP biosynthetic process  transport  acidic amino acid transmembrane transporter activity  L-aspartate transmembrane transporter activity  aspartate transport  L-glutamate transport  malate-aspartate shuttle  cellular respiration  response to calcium ion  L-glutamate transmembrane transport  L-glutamate transmembrane transport  L-aspartate transmembrane transport  L-aspartate transmembrane transport  
Ontology : EGO-EBIstructural constituent of ribosome  transporter activity  L-glutamate transmembrane transporter activity  calcium ion binding  mitochondrion  mitochondrial inner membrane  mitochondrial inner membrane  integral component of plasma membrane  gluconeogenesis  translation  ATP biosynthetic process  transport  acidic amino acid transmembrane transporter activity  L-aspartate transmembrane transporter activity  aspartate transport  L-glutamate transport  malate-aspartate shuttle  cellular respiration  response to calcium ion  L-glutamate transmembrane transport  L-glutamate transmembrane transport  L-aspartate transmembrane transport  L-aspartate transmembrane transport  
NDEx NetworkSLC25A13
Atlas of Cancer Signalling NetworkSLC25A13
Wikipedia pathwaysSLC25A13
Orthology - Evolution
OrthoDB10165
GeneTree (enSembl)ENSG00000004864
Phylogenetic Trees/Animal Genes : TreeFamSLC25A13
HOVERGENQ9UJS0
HOGENOMQ9UJS0
Homologs : HomoloGeneSLC25A13
Homology/Alignments : Family Browser (UCSC)SLC25A13
Gene fusions - Rearrangements
Fusion : MitelmanEXOC4/SLC25A13 [7q33/7q21.3]  [t(7;7)(q21;q33)]  
Fusion : MitelmanSLC25A13/SHFM1 [7q21.3/7q21.3]  [dup(7)(q21q21)]  
Fusion : MitelmanSLC25A13/STK31 [7q21.3/7p15.3]  [t(7;7)(p15;q21)]  
Fusion: TCGAEXOC4 7q33 SLC25A13 7q21.3 BRCA
Fusion: TCGASLC25A13 7q21.3 STK31 7p15.3 BRCA
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC25A13 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC25A13
dbVarSLC25A13
ClinVarSLC25A13
1000_GenomesSLC25A13 
Exome Variant ServerSLC25A13
ExAC (Exome Aggregation Consortium)SLC25A13 (select the gene name)
Genetic variants : HAPMAP10165
Genomic Variants (DGV)SLC25A13 [DGVbeta]
DECIPHER (Syndromes)7:95749532-95951459  ENSG00000004864
CONAN: Copy Number AnalysisSLC25A13 
Mutations
ICGC Data PortalSLC25A13 
TCGA Data PortalSLC25A13 
Broad Tumor PortalSLC25A13
OASIS PortalSLC25A13 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC25A13  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC25A13
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch SLC25A13
DgiDB (Drug Gene Interaction Database)SLC25A13
DoCM (Curated mutations)SLC25A13 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC25A13 (select a term)
intoGenSLC25A13
Cancer3DSLC25A13(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM603471    603859    605814   
Orphanet19528    19529   
MedgenSLC25A13
Genetic Testing Registry SLC25A13
NextProtQ9UJS0 [Medical]
TSGene10165
GENETestsSLC25A13
Huge Navigator SLC25A13 [HugePedia]
snp3D : Map Gene to Disease10165
BioCentury BCIQSLC25A13
ClinGenSLC25A13
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD10165
Chemical/Pharm GKB GenePA35859
Clinical trialSLC25A13
Miscellaneous
canSAR (ICR)SLC25A13 (select the gene name)
Probes
Litterature
PubMed91 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC25A13
EVEXSLC25A13
GoPubMedSLC25A13
iHOPSLC25A13
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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indexed on : Fri Nov 18 19:51:34 CET 2016

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