SLC25A14 (solute carrier family 25 member 14)

2016-10-01 Affiliation

Identity

HGNC

SLC25A14

LOCATION

Xq26.1

LOCUSID

9016

ALIAS

BMCP1,UCP5

FUSION GENES

Show Gene Fusions

Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool

Other Information

Locus ID:

NCBI: 9016
MIM: 300242
HGNC: 10984
Ensembl: ENSG00000102078

Variants:

dbSNP: 9016
ClinVar: 9016
TCGA: ENSG00000102078
COSMIC: SLC25A14

RNA/Proteins

Gene ID	Transcript ID	Uniprot
ENSG00000102078	ENST00000218197	O95258
ENSG00000102078	ENST00000339231	O95258
ENSG00000102078	ENST00000361980	O95258
ENSG00000102078	ENST00000424447	Q5JY88
ENSG00000102078	ENST00000543953	F6SL11
ENSG00000102078	ENST00000545805	O95258
ENSG00000102078	ENST00000612248	O95258

Expression (GTEx)

Adipose - Subcutaneous

Adipose - Visceral

Adrenal Gland

Artery - Aorta

Artery - Tibial

Bladder

Brain - Amygdala

Brain - Anterior cingulate cortex

Brain - Caudate

Brain - Cerebellar Hemisphere

Brain - Cerebellum

Brain - Cortex

Brain - Frontal Cortex

Brain - Hippocampus

Brain - Hypothalamus

Brain - Nucleus accumbens

Brain - Putamen

Brain - Spinal cord

Brain - Substantia nigra

Breast - Mammary Tissue

Cells - Cultured fibroblasts

Cells - EBV - transformed lymphocytes

Cervix - Ectocervix

Cervix - Endocervix

Colon - Sigmoid

Colon - Transverse

Esophagus - Gastroesophageal Junction

Esophagus - Mucosa

Esophagus - Muscularis

Fallopian Tube

Heart - Atrial Appendage

Heart - Left Ventricle

Kidney - Cortex

Kidney - Medulla

Liver

Lung

Minor Salivary Gland

Muscle - Skeletal

Nerve - Tibial

Ovary

Pancreas

Pituitary

Prostate

Skin - Not Sun Exposed

Skin - Sun Exposed

Small Intestine - Terminal Ileum

Spleen

Stomach

Testis

Thyroid

Uterus

Vagina

Whole Blood

Pathways

Pathway	Source	External ID
Metabolism	REACTOME	R-HSA-1430728
The citric acid (TCA) cycle and respiratory electron transport	REACTOME	R-HSA-1428517
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.	REACTOME	R-HSA-163200
Mitochondrial Uncoupling Proteins	REACTOME	R-HSA-166187
The fatty acid cycling model	REACTOME	R-HSA-167826
The proton buffering model	REACTOME	R-HSA-167827

References

Pubmed ID	Year	Title	Citations
23266187	2013	The mitochondrial transporter family SLC25: identification, properties and physiopathology.	159
22087257	2011	Association of the sirtuin and mitochondrial uncoupling protein genes with carotid plaque.	24
22524567	2012	Toward understanding the mechanism of ion transport activity of neuronal uncoupling proteins UCP2, UCP4, and UCP5.	18
18018477	2007	Amplified expression of uncoupling proteins in human brain ischemic lesions.	15
17066476	2007	Synergistic association of mitochondrial uncoupling protein (UCP) genes with schizophrenia.	14
17066476	2007	Synergistic association of mitochondrial uncoupling protein (UCP) genes with schizophrenia.	14
16941493	2006	Knockdown of uncoupling protein-5 in neuronal SH-SY5Y cells: Effects on MPP+-induced mitochondrial membrane depolarization, ATP deficiency, and oxidative cytotoxicity.	13
19910678	2009	Hydrogen peroxide regulates the mitochondrial content of uncoupling protein 5 in colon cancer cells.	10
12051969	2002	UCP5/BMCP1 transcript isoforms in human skeletal muscle: relationship of the short-insert isoform with lipid oxidation and resting metabolic rates.	4
23266757	2013	Evidence for involvement of uncoupling proteins in cerebral mitochondrial oxidative phosphorylation deficiency of rats exposed to 5,000 m high altitude.	1

Citation

Dessen P

SLC25A14 (solute carrier family 25 member 14)

Atlas Genet Cytogenet Oncol Haematol. 2016-10-01

Online version: http://atlasgeneticsoncology.org/gene/56265/slc25a14