Atlas of Genetics and Cytogenetics in Oncology and Haematology

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SLC25A21 (solute carrier family 25 member 21)

Identity

Alias_namessolute carrier family 25 (mitochondrial oxodicarboxylate carrier), member 21
solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
Alias_symbol (synonym)ODC1
ODC
Other alias
HGNC (Hugo) SLC25A21
LocusID (NCBI) 89874
Atlas_Id 73344
Location 14q13.3  [Link to chromosome band 14q13]
Location_base_pair Starts at 36677921 and ends at 37172660 bp from pter ( according to hg38-Dec_2013)
Fusion genes
(updated 2017)		Data from Atlas, Mitelman, Cosmic Fusion, Fusion Cancer, TCGA fusion databases with official HUGO symbols (see references in chromosomal bands)
C14orf166 (14q22.1) / SLC25A21 (14q13.3)FOXN3 (14q31.3) / SLC25A21 (14q13.3)MARK3 (14q32.32) / SLC25A21 (14q13.3)
NAA25 (12q24.13) / SLC25A21 (14q13.3)NKX2-1 (14q13.3) / SLC25A21 (14q13.3)RALGAPA1 (14q13.2) / SLC25A21 (14q13.3)
SLC25A21 (14q13.3) / MIPOL1 (14q13.3)NAA25 SLC25A21FOXN3 SLC25A21
NKX2-1 SLC25A21

Note

Non-annotated gene. Preliminary data : if you are an author
who wish to write a full paper/card on this gene, go to  How to contribute

DNA/RNA

 

Other Solid tumors implicated (Data extracted from papers in the Atlas) [ 5 ]
  t(12;14)(q24;q13) NAA25/SLC25A21
t(14;14)(q13;q13) NKX2-1/SLC25A21
t(14;14)(q13;q13) SLC25A21/MIPOL1
t(14;14)(q13;q13) RALGAPA1/SLC25A21
t(14;14)(q13;q32) MARK3/SLC25A21

External links

Nomenclature
HGNC (Hugo)SLC25A21   14411
Cards
Entrez_Gene (NCBI)SLC25A21  89874  solute carrier family 25 member 21
AliasesODC; ODC1
GeneCards (Weizmann)SLC25A21
Ensembl hg19 (Hinxton)ENSG00000183032 [Gene_View]
Ensembl hg38 (Hinxton)ENSG00000183032 [Gene_View]  chr14:36677921-37172660 [Contig_View]  SLC25A21 [Vega]
ICGC DataPortalENSG00000183032
TCGA cBioPortalSLC25A21
AceView (NCBI)SLC25A21
Genatlas (Paris)SLC25A21
WikiGenes89874
SOURCE (Princeton)SLC25A21
Genetics Home Reference (NIH)SLC25A21
Genomic and cartography
GoldenPath hg38 (UCSC)SLC25A21  -     chr14:36677921-37172660 -  14q13.3   [Description]    (hg38-Dec_2013)
GoldenPath hg19 (UCSC)SLC25A21  -     14q13.3   [Description]    (hg19-Feb_2009)
EnsemblSLC25A21 - 14q13.3 [CytoView hg19]  SLC25A21 - 14q13.3 [CytoView hg38]
Mapping of homologs : NCBISLC25A21 [Mapview hg19]  SLC25A21 [Mapview hg38]
OMIM607571   
Gene and transcription
Genbank (Entrez)AJ278148 AK289575 BC101521 BC113365 HQ258164
RefSeq transcript (Entrez)NM_001171170 NM_030631
RefSeq genomic (Entrez)
Consensus coding sequences : CCDS (NCBI)SLC25A21
Cluster EST : UnigeneHs.730857 [ NCBI ]
CGAP (NCI)Hs.730857
Alternative Splicing GalleryENSG00000183032
Gene ExpressionSLC25A21 [ NCBI-GEO ]   SLC25A21 [ EBI - ARRAY_EXPRESS ]   SLC25A21 [ SEEK ]   SLC25A21 [ MEM ]
Gene Expression Viewer (FireBrowse)SLC25A21 [ Firebrowse - Broad ]
SOURCE (Princeton)Expression in : [Datasets]   [Normal Tissue Atlas]  [carcinoma Classsification]  [NCI60]
GenevestigatorExpression in : [tissues]  [cell-lines]  [cancer]  [perturbations]  
BioGPS (Tissue expression)89874
GTEX Portal (Tissue expression)SLC25A21
Human Protein AtlasENSG00000183032-SLC25A21 [pathology]   [cell]   [tissue]
Protein : pattern, domain, 3D structure
UniProt/SwissProtQ9BQT8   [function]  [subcellular_location]  [family_and_domains]  [pathology_and_biotech]  [ptm_processing]  [expression]  [interaction]
NextProtQ9BQT8  [Sequence]  [Exons]  [Medical]  [Publications]
With graphics : InterProQ9BQT8
Splice isoforms : SwissVarQ9BQT8
PhosPhoSitePlusQ9BQT8
Domaine pattern : Prosite (Expaxy)SOLCAR (PS50920)   
Domains : Interpro (EBI)Mit_carrier    Mitochondrial_sb/sol_carrier    Mt_carrier_dom   
Domain families : Pfam (Sanger)Mito_carr (PF00153)   
Domain families : Pfam (NCBI)pfam00153   
Conserved Domain (NCBI)SLC25A21
DMDM Disease mutations89874
Blocks (Seattle)SLC25A21
SuperfamilyQ9BQT8
Human Protein Atlas [tissue]ENSG00000183032-SLC25A21 [tissue]
Peptide AtlasQ9BQT8
HPRD12124
IPIIPI00012690   IPI00954991   
Protein Interaction databases
DIP (DOE-UCLA)Q9BQT8
IntAct (EBI)Q9BQT8
FunCoupENSG00000183032
BioGRIDSLC25A21
STRING (EMBL)SLC25A21
ZODIACSLC25A21
Ontologies - Pathways
QuickGOQ9BQT8
Ontology : AmiGO###############################################################################################################################################################################################################################################################                    
Ontology : EGO-EBI###############################################################################################################################################################################################################################################################                    
NDEx NetworkSLC25A21
Atlas of Cancer Signalling NetworkSLC25A21
Wikipedia pathwaysSLC25A21
Orthology - Evolution
OrthoDB89874
GeneTree (enSembl)ENSG00000183032
Phylogenetic Trees/Animal Genes : TreeFamSLC25A21
HOVERGENQ9BQT8
HOGENOMQ9BQT8
Homologs : HomoloGeneSLC25A21
Homology/Alignments : Family Browser (UCSC)SLC25A21
Gene fusions - Rearrangements
Fusion: TCGA_MDACCNAA25 SLC25A21
Fusion: TCGA_MDACCFOXN3 SLC25A21
Fusion: TCGA_MDACCNKX2-1 SLC25A21
Fusion PortalNAA25 SLC25A21
Fusion PortalFOXN3 SLC25A21
Fusion PortalNKX2-1 SLC25A21
Fusion : QuiverSLC25A21
Polymorphisms : SNP and Copy number variants
NCBI Variation ViewerSLC25A21 [hg38]
dbSNP Single Nucleotide Polymorphism (NCBI)SLC25A21
dbVarSLC25A21
ClinVarSLC25A21
1000_GenomesSLC25A21 
Exome Variant ServerSLC25A21
ExAC (Exome Aggregation Consortium)ENSG00000183032
GNOMAD BrowserENSG00000183032
Genetic variants : HAPMAP89874
Genomic Variants (DGV)SLC25A21 [DGVbeta]
DECIPHERSLC25A21 [patients]   [syndromes]   [variants]   [genes]  
CONAN: Copy Number AnalysisSLC25A21 
Mutations
ICGC Data PortalSLC25A21 
TCGA Data PortalSLC25A21 
Broad Tumor PortalSLC25A21
OASIS PortalSLC25A21 [ Somatic mutations - Copy number]
Somatic Mutations in Cancer : COSMICSLC25A21  [overview]  [genome browser]  [tissue]  [distribution]  
Mutations and Diseases : HGMDSLC25A21
LOVD (Leiden Open Variation Database)Whole genome datasets
LOVD (Leiden Open Variation Database)LOVD - Leiden Open Variation Database
LOVD (Leiden Open Variation Database)LOVD 3.0 shared installation
LOVD (Leiden Open Variation Database)MSeqDR-LSDB Mitochondrial Disease Locus Specific Database
BioMutasearch SLC25A21
DgiDB (Drug Gene Interaction Database)SLC25A21
DoCM (Curated mutations)SLC25A21 (select the gene name)
CIViC (Clinical Interpretations of Variants in Cancer)SLC25A21 (select a term)
intoGenSLC25A21
Cancer3DSLC25A21(select the gene name)
Impact of mutations[PolyPhen2] [SIFT Human Coding SNP] [Buck Institute : MutDB] [Mutation Assessor] [Mutanalyser]
Diseases
OMIM607571   
Orphanet
DisGeNETSLC25A21
MedgenSLC25A21
Genetic Testing Registry SLC25A21
NextProtQ9BQT8 [Medical]
TSGene89874
GENETestsSLC25A21
Target ValidationSLC25A21
Huge Navigator SLC25A21 [HugePedia]
snp3D : Map Gene to Disease89874
BioCentury BCIQSLC25A21
ClinGenSLC25A21
Clinical trials, drugs, therapy
Chemical/Protein Interactions : CTD89874
Chemical/Pharm GKB GenePA37880
Clinical trialSLC25A21
Miscellaneous
canSAR (ICR)SLC25A21 (select the gene name)
Probes
Litterature
PubMed13 Pubmed reference(s) in Entrez
GeneRIFsGene References Into Functions (Entrez)
CoreMineSLC25A21
EVEXSLC25A21
GoPubMedSLC25A21
iHOPSLC25A21
Genes in titleautomatic search in PubMed
REVIEW articlesautomatic search in PubMed
Last year publicationsautomatic search in PubMed

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© Atlas of Genetics and Cytogenetics in Oncology and Haematology
indexed on : Fri Feb 23 18:51:29 CET 2018
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